China
Africa
Explore chapters and articles related to this topic
Pharmacology of Male Sexual Function
Published in Karl H. Pang, Nadir I. Osman, James W.F. Catto, Christopher R. Chapple, Basic Urological Sciences, 2021
Andrei Kozan, Weida Lau, Oliver Kayes
SSRIs are typically prescribed for the treatment of depression.Common side effects: delayed ejaculation and anorgasmia.
The Effects of Pharmaceuticals, Environmental, and Occupational Agents on Sperm Motility
Published in Claude Gagnon, Controls of Sperm Motility, 2020
Chlorpromazine is an antipsychotic drug capable of relieving certain symptoms in schizophrenic patients. Side effects of this drug include delayed ejaculation and weakened erection. No other adverse reproductive effects have yet been reported. However, several studies have shown that chlorpromazine can inhibit the motility of bull,73 dog,74 frog,75 rabbit, and human sperm in vitro.76-78
What to do if nothing wrong can be found and how to answer when a couple asks ‘what can we do to improve our fertility?’
Published in David J Cahill, Practical Patient Management in Reproductive Medicine, 2019
In Chapter 5, antipsychotics and H2 blockers were mentioned, which are recognised to have a detrimental effect on fertility, through their influence on prolactin levels or weight gain (92). If the female partner has to take these medications, she should continue to do so. These drugs may affect natural conception, but once exogenous gonadotrophins are introduced, any effects of prolactin will be overruled by the gonadotrophin therapy. A 2019 review of selective serotonin reuptake inhibitors (SSRIs) examined 16 original papers on SSRI impact on fertility (88). Of seven studies in women, six papers found no significant association between SSRIs and treatment outcomes; in men, a similar number of papers were found to have an adverse effect on semen parameters. In men, sperm numbers are reduced, and DNA integrity damage increased. In addition, problems of reduced libido, erectile dysfunction and delayed ejaculation are noted (88).
The effects of selective serotonin reuptake inhibitors on male and female fertility: a brief literature review
Published in International Journal of Psychiatry in Clinical Practice, 2022
Jovana Z. Milosavljević, Miloš N. Milosavljević, Petar S. Arsenijević, Milica N. Milentijević, Srđan M. Stefanović
Due to the fact that SSRIs delay ejaculation in men, they are successfully used to treat premature ejaculation (PE) (Waldinger et al. 2004), with dapoxetine being particularly effective (McMahon 2011). Delaying ejaculation in patients with PE improves the quality of sexual intercourse and increases coital frequency, so that SSRIs can positively affect fertility. On the other hand, excessive delay in ejaculation can also indirectly increase the risk of infertility (Kondoh 2012). Therefore, the use of SSRIs in patients with initially normal ejaculatory function may reduce the likelihood of conception if delayed ejaculation occurs as an adverse effect. Other sexual side effects of SSRIs, such as decreased libido and erectile dysfunction, can also have negative consequences for conception (Berger et al. 2016).
Sexual equity and the good enough sex model
Published in Sexual and Relationship Therapy, 2020
Barry McCarthy, Danielle Cohn, Candace A. Koman
Males are socialized to only accept perfect individual sex performance featuring predictable erection, intercourse, and orgasm. The male performance model is the main cause of secondary male Hypoactive Sexual Desire Disorder, which involves frustration, embarrassment, and eventually sexual avoidance (Zilbergeld, 1999). When couples stop being sexual, it is almost always the man’s choice made unilaterally and conveyed non-verbally (McKinlay & Feldman, 1994). Sexual dysfunction, especially secondary erectile dysfunction and secondary ejaculatory inhibition (delayed ejaculation) is the most common cause (Lindau et al., 2007). Although pro-erection medication and other medical interventions can be valuable resources, they are not stand-alone interventions. The man, with the woman’s support and encouragement, needs to adopt GES as the prime strategy. The clinical adage is: “Traditional men stop being sexual in their 50s or 60s. ‘Wise men’ adopt GES and are sexual in their 60s, 70s, and 80s” (McCarthy, 2015).
Factors Associated with Sexual Dysfunction Symptoms among Veterans who Have Experienced Military Sexual Trauma
Published in International Journal of Sexual Health, 2018
Jade Garneau-Fournier, Janice Habarth, Jessica A. Turchik
Several variables were found to be significantly related to delayed ejaculation symptoms: being married compared to being divorced/separated, using an SSRI/Effexor, endorsing symptoms of PTSD or substance use disorder, and reporting a history of combat exposure. The relationship between delayed ejaculation and SSRI/Effexor use is consistent with the literature (Breyer et al., 2014; Rosen et al., 1999). Little is known about specific mental health factors being predictive of delayed ejaculation among male veterans, given that most research on SD types among this population has focused on sexual desire and sexual arousal symptoms (Tran et al., 2015; Wilcox et al., 2014). Consistent with previous findings suggesting that orgasmic functioning is impaired in veterans without PTSD (Cosgrove et al., 2002), the current study demonstrated that delayed ejaculation was significantly related to PTSD symptoms. One explanation for this relationship is that intrusive symptoms characteristic of PTSD may interfere with men's ability to reach orgasm and thus delay the time of ejaculation (Tran et al., 2015). Moreover, the physiological response during sexual arousal mirrors a fear response which may inhibit ejaculatory function (Yehuda et al., 2015). Lastly, the finding that combat exposure was specifically related to delayed ejaculation even when controlling for depression and PTSD was unanticipated and warrants further investigation.