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Special Care Units
Published in William C. Beck, Ralph H. Meyer, The Health Care Environment: The User’s Viewpoint, 2019
Dialysis as a special section in a hospital is one of the rather recent contributions to the hospital art. There will, in the future, undoubtedly be others. Each will have its own list of requirments. Each will need to have individual consideration. It is for this reason that modularity in the overall structure of institutions appears to be so attractive, particularly for the users who develop new and innovative diagnostic and therapeutic technology.
Developing New Ventures
Published in Ruchin Kansal, Jeff Huth, Redefining Innovation, 2018
Doors and windows are designed to fit standard openings in building construction. Locksets manufactured by different manufacturers can fit the doors and windows from any manufacturer. Faucets are designed to fit in bathroom or kitchen sinks produced by various manufacturers. Modular doesn't get simpler than this. It is akin to the concept of interoperability in the technology industry. Some would say that the pharmaceutical pill is very modular. You take it out of its package and ingest it. Digital therapeutics incorporate inherent modular properties. They can be developed to complement a specific biopharmaceutical product, function across an entire therapeutic category, or exert their effect independent of any conventional product. Modularity, if applied to healthcare, can solve for rapid adoption of new ventures in the highly complex healthcare ecosystem.
Advances in Primary and Revision Hip Arthroplasty
Published in K. Mohan Iyer, Hip Joint in Adults: Advances and Developments, 2018
Shibu P. Krishnan, G. Gopinath
While modularity affords clear advantages, it also brings in additional risks. It is prudent to advance the stem designs by introducing incremental changes over a period with stringent monitoring using mechanisms such as beyond compliance.
Decomposition of micromotion at the head-neck interface in total hip arthroplasty during walking
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2023
Guoxian Zhang, Shu Yang, Wen Cui, Zhi Huang, Xiaogang Zhang, Yali Zhang, Junyan Li, Zhongmin Jin
Modular hip prosthesis through the morse taper connection has been popular in total hip replacement (THR). Modularity provides more flexible options in material couplings and geometrical adjustments according to anatomical features and needs of patients. However, a considerable case has grown up around implant failure attributed to metal ions and debris at the taper junction (Meyer et al. 2012; Nassif et al. 2014; Berstock et al. 2018), which has aroused great concern about the modular interface. Also, retrieval studies reported various failure types of head-neck junction, such as fretting and crevice corrosion (Pivec et al. 2014). It is generally believed that micromotion at the head-neck junction can damage the passivation layer of the metal surface and expose the bare metal to the corrosive environment, resulting in continuous material degradation.
Effects of domotics on cognitive, social and personal functioning in patients with Parkinson’s disease: A pilot study
Published in Assistive Technology, 2022
Desiree Latella, Maria Grazia Maggio, Giuseppa Maresca, Adriana Andaloro, Smeralda Anchesi, Valentina Pajno, Rosaria De Luca, Giuseppe Di Lorenzo, Alfredo Manuli, Rocco Salvatore Calabrò
Some studies have shown that the introduction of new technologies at home, such as robots and sensors, combined with innovative tools, allows the creation of environments in which it is possible to provide assistance while maintaining vital capacity, autonomy, and satisfying patient’s needs (Jung et al., 2005; Kanemura et al., 2013; Miori et al., 2012). This is the reason why the objective of HA is the maintenance or improvement of one’s independence. These positive effects may be due to the fact that HA might encourage a greater involvement of the patient. Some specific features of the tool, such as modularity, personalization of the skills, and system implementation, can facilitate patient’s return home and autonomy (Bolzani et al., 2006; Meulendijk et al., 2011; Morón et al., 2016). Therefore, it is very important to investigate how technologies applied to the rehabilitation field can be useful to better manage neurodegenerative diseases, with regard to quality of life and social problems (Barone et al., 2017; Maggio et al., 2020). To this end, through assistive technology patients would perceive a better control of their behavior and organize it in a functional way to achieve the objectives, with positive repercussions in the autonomy of life (Ginnavaram et al., 2020; Hu & Chomiak, 2019; Maggio et al., 2020; Riva, 2003; Rosner et al., 2015; Tewell et al., 2019).
Changing the pill: developments toward the promise of an ultra-long-acting gastroretentive dosage form
Published in Expert Opinion on Drug Delivery, 2018
David H. Altreuter, Ameya R. Kirtane, Tyler Grant, Cecilia Kruger, Giovanni Traverso, Andrew M. Bellinger
As the research described above indicates, design and material considerations are key in systematically addressing the barriers to gastric retention, and the evolution of new materials will likely remain a key area for advancement of long-term gastric retention in the future. Modularity is one approach which offers better control over key functional requirements by dividing the critical needs across multiple features and materials. A composite design should also offer the ability to tune properties and strategies depending on the unique requirements of each product, whether tunable duration or different physiochemical requirements of the drug. The tradeoff of modularity and multiple materials, however, is greater product complexity and manufacturing requirements. Opportunities for advancement include the development of: (a) more predictive in vitro assays for in vivo performance, particularly with respect to complex properties like timing of gastric exit; (b) physiologically responsive materials with predictable properties in the stomach; (c) strategies for stabilizing unstable drugs; (d) more low-dose oral drugs that could enable long-acting therapies for diseases where current options are limited (i.e. HIV or epilepsy); and (e) evidence of translation of GRDFs into human populations with varying gastric physiologies.