Sambucus ebulus – Knowledge and References

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Medicinal Plants Against COVID-19

Published in Hanadi Talal Ahmedah, Muhammad Riaz, Sagheer Ahmed, Marius Alexandru Moga, The Covid-19 Pandemic, 2023

Binish Khaliq, Naila Ali, Ahmed Akrem, M. Yasin Ashraf, Arif Malik, Arifa Tahir, M. Zia-Ul-Haq

Lectins present in Sambucus ebulus have the ability to restrict the entry of enveloped viruses, although its mechanism is not known. Quertin and isorhamnetin, which are phenolic compounds in the same plant, combate Ebola virus (EBOV) while, diosgenin, and yomogenin are the flavonoids and have the ability to inhibit the entry of hepatitis C viruses (HCV) [177].

Topical therapies for knee osteoarthritis

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Journal Information

Published in Postgraduate Medicine, 2018

E. C. Rodriguez-Merchan

A pilot study concluded that topical treatment with Sambucus ebulus L. (S. ebulus) gel can be advised for improving symptoms of patients with knee OA [17]. Jabbari et al. analyzed 79 patients with knee OA. They were randomly enrolled in two parallel arms of a pilot randomized, double-blind, active-controlled clinical trial. The patients were treated by topical S. ebulus gel or 1% diclofenac gel, three times a day, as much as a fingertip unit for 4 weeks. Patients were assessed prior to enrollment and, then, 2 and 4 weeks subsequent to the intervention, in terms of scores of VAS for self-grading of their knee joint pain, and according to three different domains of WOMAC questionnaire. Any observed adverse effects were also scrutinized. The mean values of WOMAC pain score, total WOMAC score, and VAS score for pain of the S. ebulus group were significantly lower compared with the diclofenac group. In addition, no serious adverse effect was reported.