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Advances in Nanonutraceuticals: Indian Scenario
Published in Harishkumar Madhyastha, Durgesh Nandini Chauhan, Nanopharmaceuticals in Regenerative Medicine, 2022
Amthul Azeez, Mubeen Sultana, Lucky, Noorjahan
Mimosa pudica known as chuemue is a shrub by plant with compound leaves that are sensitive on touching and grows as a weed in almost all parts of the country. The leaves have alkaloids, mimosine and mucilage, whereas the root contains tannins. It is used for its anti-hyperglycemic, anti-diarrhoeal, anticonvulsant and cytotoxic properties. Leaves and roots of the plant are utilised to treat piles and fistula. The plant is also used in the treatment of sore gum, as a blood purifier. M. pudica is also used in ayurvedic and the Unani system of medicine for treating diseases such as piles, jaundice, leprosy, ulcers, bilious fever and small pox (Rekha et al. 2009).
Pathological Processes of the Eye Related to Chemical Exposure
Published in David W. Hobson, Dermal and Ocular Toxicology, 2020
Antimetabolites — This is a group of chemicals that in some way interfere with enzyme action or formation of lens proteins. The result is cataract formation. Examples of these chemicals are chlorophenylalanine, phenylhydrazopropionitrile, mimosine, dichloronitroaniline, and naphthalene and related compounds.
Herbs with Antidepressant Effects
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
The primary compounds isolated from Mimosa pudica are crocetin, crocin, 6-hydroxy flavone (2), 2'-hydroxy flavanone, p-coumaric acid, p-hydroxy benzoic acid, chlorogenic acid, jasmonic acid, and L-mimosine, caffeic acid (7), ethyl gallate (3), catechin (9), and gallic acid.2 Some of these phytochemicals are shared by other medicinal plants, several of which have been found to have antidepressant effects in animals and humans.
Metabolomic Profile in the Aqueous Humor of Congenital Ectopia Lentis
Published in Current Eye Research, 2023
Liyan Liu, Yiqing Li, Dongwei Guo, Huiwen Ye, Haotian Qi, Bin Zou, Danying Zheng, Guangming Jin
Besides, we assessed the impact of 175 metabolites by ROC analysis. The results indicated that eight metabolites could serve as potential biomarkers in AH for a good discrimination between CEL and controls. Pelargonidin is a phenolic substance with antioxidant activity that could reduce intraocular pressure and oxidative damage, and prevent the development of glaucoma by maintaining antioxidant enzyme levels.53 Petunidin, an anthocyanin, also has antioxidant activity and was reported to inhibit lens opacity.54 Mimosine is a nonprotein amino acid, tyrosine analogue, that can chelate iron to block the normal mammalian cell cycle,55 activate apoptosis, and induce reactive oxygen species production.56 These results may be related to the final phenotype of the disease. However, since very scant information is available about the role of these substances in ocular diseases, it is difficult to determine the deeper internal association.
Antidiabetic and antihyperlipidemic effects of a methanolic extract of Mimosa pudica (Fabaceae) in diabetic rats
Published in Egyptian Journal of Basic and Applied Sciences, 2019
Subramani Parasuraman, Teoh Huey Ching, Chong Hao Leong, Urmila Banik
Mimosa pudica Linn. is a creeping annual or perennial herb often grown for its curiosity value, as the compound leaves fold inward and droop when touched and reopens within minutes. Mimosa is a genus of about 400 species of herbs and shrubs, in the subfamily Mimosoideae of the Legume family Fabaceae. The plant is a native of tropical America and naturalized nearly all through the tropical and subtropical parts of India. It is commonly distributed in open spaces, such as waste area, roadside, agricultural land, and natural forests. Phytomedicines potentially benefit to the community thus they are still being practiced in all traditional systems of therapies, including Greco-Arab (Unani-Tibb), Ayurveda, and Chinese medicine [18]. Phytochemical studies on Mimosapudica have revealed the presence of alkaloids, non-protein amino acid (mimosine), flavonoids C-glycosides, sterols, terpenoids, tannins, and fatty acids. In the phytochemical analysis, the root of Mimosa pudica showed the presence of ascorbic acid, crocetin, D-glucuronic acid, linoleic acid, linolenic acid, palmitic and stearic acids, mimosine, D-xylose, and b-sitosterols. Bufadienolide, D-pinitol, norepinephrine, P-coumaric acid, mimopudine, and mimosine are some of the isolated secondary metabolites of Mimosa pudica [19].
Anti-Gastric Cancer Effect of Purified Omphalia lapidescens Protein via Regulating the JAK/STAT3 Signaling Pathway
Published in Nutrition and Cancer, 2022
Yuqin Xu, Wenjun Xu, Zhongxia Lu, Man Hei Cheung, Meiai Lin, Chun Liang, Jianshu Lou, Yitao Chen
Cells were inoculated on 96-well plate at a density of 2 × 104 cells per well and cultured with L-Mimosine (50 mM) for 24 h at 37 °C. Subsequently, cells were treated with culture medium, pPeOp (60 µg/ml), IL-6 (100 ng/ml), pPeOp (60 µg/ml) and IL-6 (100 ng/ml), NSC74859 (100 ng/ml), pPeOp (60 µg/ml) and NSC74859 (100 ng/ml) for 24 h, respectively. 20 µl MTS (Promega Corporation) were added to each well, agitated lightly for 30 s, and then incubated for 2 h at 37 °C in the dark. The optical density (OD) was measured at 490 nm using a microplate reader (Labsystems).