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Cefotiam, Cefuzonam, Cefamandole, Cefonicid, and Ceforanide
Published in M. Lindsay Grayson, Sara E. Cosgrove, Suzanne M. Crowe, M. Lindsay Grayson, William Hope, James S. McCarthy, John Mills, Johan W. Mouton, David L. Paterson, Kucers’ The Use of Antibiotics, 2017
Hisashi Baba, David L. Paterson
Cefotiam is active against Escherichia coli and Klebsiella. Proteus mirabilis is less sensitive to cefotiam, and other Proteus spp., Serratia marcescens, Enterobacter aerogenes, Citrobacter freundii, and Morganella morganii are resistant (Yamaguchi et al., 2012; Yamaguchi et al., 2014; Yoshida et al., 2012b). Cefotiam lacks antipseudomonal activity.
Clinical Values of Preoperative Use of Antibiotics in Transanal Endoscopic Microsurgery
Published in Journal of Investigative Surgery, 2018
Jingbo Chen, Yupeng Li, Xiangpeng Xi, Lili Qiao, Mingyu Yang, Lijian Xia, Yanbing Zhou
In the antibiotic group, preoperative 30–60 min the patients were injected with cefotiam hydrochloride 2 g + 0.9% normal saline 100 mL undergoing intravenous infusion and 0.5 – 1 h drop out. The control group was received the same amount 0.9% normal saline only, and taken the same method for intravenous infusion. After surgery, both groups were injected with cefotiam hydrochloride 2 g + 0.9% normal saline 100 mL, and 250 mL metronidazole undergoing intravenous infusion. Postoperative application of antibiotics for 3 days, for preoperative infection or larger surgical wound, it was prolong to 4–5 days appropriately.
Successful Treatment of Hypersplenism in Wilson's Disease by Partial Splenic Embolization
Published in Journal of Investigative Surgery, 2018
Liang-Yong Li, Huai-Zhen Chen, Yuan-Cheng Bao, Qing-Sheng Yu, Wen-Ming Yang
Patients in group B underwent splenectomy under general anesthesia (general anesthesia was induced with 8–30 μg, 0.05–0.075 mg/kg midazolam, 0.3–0.6 mg/kg atracurium, and maintained with 4–12 mg/kg/h propofol, 5-10 μg/kg/min atracurium, and 0.1–2 μg/kg/min remifentanil; anesthesia time was approximately 90 to 120 min). Prophylactic systemic intravenous antibiotics (cefotiam 1 g every 12 hr for 5 days) were administered 1 week before the operation as well as several days postoperatively.
Comparison of antibiotics use, urinary tract infection (UTI)-causative bacteria and their antibiotic susceptibilities among 4 hospitals with different backgrounds and regions in Japan
Published in Journal of Chemotherapy, 2018
Katsumi Shigemura, Koichi Kitagawa, Kayo Osawa, Fukashi Yamamichi, Issei Tokimatsu, Masashi Nomi, Kei Takaba, Masato Fujisawa
Antimicrobial susceptibility testing was performed for the following antibiotics including ampicillin (ABPC), ampicillin/sulbactam (ABPC/SBT), piperacillin (PIPC), piperacillin/tazobactam (PIPC/TAZ), cefotiam (CTM), cefmetazole (CMZ), flomoxef (FMOX), cefotaxime (CTX), ceftazidime (CAZ), cefazolin (CEZ), cefepime (CFPM), imipenem (IPM), meropenem (MEPM), gentamicin (GM), amikacin (AMK) and levofloxacin (LVFX), according to CLSI guideline.9