China
Africa
Explore chapters and articles related to this topic
Oral Health
Published in K. Balamurugan, U. Prithika, Pocket Guide to Bacterial Infections, 2019
Ana Moura Teles, José Manuel Cabeda
The microbiomes of endodontic-periodontal lesions, which evolve simultaneous infection of pulpal space and of the periodontum, possessed similar profiles including E. faecalis, P. micra, Mogibacterium timidum, Filifactor alocis, and Fretibacterium fastidiosum (Gomes et al. 2015).
The pathogenic oral–gut–liver axis: new understandings and clinical implications
Published in Expert Review of Clinical Immunology, 2021
Jin Imai, Sho Kitamoto, Nobuhiko Kamada
Nakatsu and colleagues reported that the enrichment of specific bacterial taxa in humans is an early sign of dysbiosis in adenoma, and coexclusive relationships are subsequently more common in cancer [45]. Another study of patients with adenomas identified multiple taxa that were significantly more abundant, including Bilophila and Desulfovibrio spp., proinflammatory bacteria in the genus Mogibacterium, and multiple species in the phylum Bacteroidetes [46]. Furthermore, increased numbers of Acinetobacter, Helicobacter, and Pseudomonas spp. have been reported in patients with rectal adenomas than in individuals without adenomas [47]. Although most CRC microbiome studies are conducted using fecal samples [48,49], some studies analyze the bacteria enriched in colorectal tissue specimens. Kostic and colleagues confirmed that Fusobacterium was enriched in carcinomas using quantitative PCR and 16S rDNA sequence analysis of 95 carcinoma/normal DNA pairs, whereas Bacteroidetes and Firmicutes were depleted [50]. These findings suggest that CRC may be initiated by modification of the balanced interaction between the host and the microbiome through the adoption of a proinflammatory profile by the intestinal microbiota [51].
Porphyromonas, Treponema, and Mogibacterium promote IL8/IFNγ/TNFα-based pro-inflammation in patients with medication-related osteonecrosis of the jaw
Published in Journal of Oral Microbiology, 2021
Qingxiang Li, Yinfei Pu, Han Lu, Ning Zhao, Yifei Wang, Yuxing Guo, Chuanbin Guo
According to De Ceulaer et al., MRONJ could be considered as a bisphosphonate-induced Actinomyces infection [16]. Most specimens (83/101) from oncological patients who had the histological confirmation of MRONJ revealed the presence of Actinomyces infection [17]. In this study, we found different bacteria distribution in MRONJ lesions and normal oral mucosa. We discovered that Porphyromonas, Treponema, and Mogibacterium detected in necrotic bone were associated with the progression of MRONJ [18,19]. A previous study used Porphyromonas in combination with alendronate to establish bisphosphonate-related osteonecrosis of the jaw (BRONJ) model in rats, which further suggested these specific bacteria might be a possible risk factor for MRONJ [20]. Treponema is a constituent of healthy oral flora, which has a vital role in periodontal disease etiology and pathogenesis; its reduction prompts the disorder of microbiota [21]. Mogibacterium is a pathogenic anaerobe that has been associated with acute dental abscess [22]. Granulicatella is one of the common health-associated commensals [23]. The changing trends of the relative abundance of these genera observed in the present study were consistent with the occurrence of MRONJ.
Identification of gut microbiome and transcriptome changes in ulcerative colitis and pouchitis
Published in Scandinavian Journal of Gastroenterology, 2022
Xin Gao, Di Huang, Li-Sheng Yang, An-Qi He, Kai-Yu Li, Tong Liu, Gang Liu
When we used LEfSe analysis to further search for different species among the subgroups, we found that Mogibacterium species increased in patients with mildly and moderately active UC, while Lachnoclostridium and Peptostreptococcus were increased in patients with severe, active UC (Figure 1(e,f)). Furthermore, Bacteroides, Roseburia and Blautia gradually decreased with the development of inflammation.