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Bacterial vaginosis in pregnancy: Evidence-based approaches
Published in Hung N. Winn, Frank A. Chervenak, Roberto Romero, Clinical Maternal-Fetal Medicine Online, 2021
James A. McGregor, Michael W. McCullough
Intravaginal treatments for bacterial vaginosis are similarly effective at eradication of bacterial vaginosis but have not been shown to improve pregnancy outcomes (38,80,82,84). Metronidazole gel 0.75% one 5-g applicator intravaginally once a day for 5 days or clindamycin 2% one 5-g applicator for 7 days is recommended. Other treatments for bacterial vaginosis have been evaluated: ampicillin, augmentin, ofloxacin, erythromycin, triple sulfa cream, and vaginal acidification (60,84). These treatments are less effective than both oral and vaginal preparations of metronidazole or clindamycin and are not recommended. Similarly, probiotic therapy with microbial products, such as lactobacillus powders and capsules, should be avoided; many of the nondairy products are contaminated with potentially harmful bacteria such as Clostridium sporogenes and Enterococcus species (85). Therapy with yogurt or acidophilus milk is also likely to be of little benefit, since the L. acidophilus strains are not easily established in the vagina (86).
Principles of Sports Nutrition
Published in Elizabeth Broad, Sports Nutrition for Paralympic Athletes, 2019
Elizabeth Broad, Louise M. Burke
Probiotics have been associated with improvements in gut barrier function, an important first “line of defence” in the immune system. There is evidence that probiotic intake can enhance the immune system, improve intestinal tract health and reduce prevalence of allergy in susceptible individuals (Bermon et al. 2017). Several large studies in athletes have provided evidence of reduced number of illness symptom days (Bermon et al. 2017, Cox et al. 2008, West et al. 2011); reduced severity of gastrointestinal symptoms, especially during long-haul travel (Walsh 2018, West et al. 2011) and improved symptoms in fatigued athletes with an identifiable immune deficiency (Clancy et al. 2006). Since there is a synergistic effect between food compounds and probiotic cultures, dairy products such as yoghurt and acidophilus milk are a good avenue for the consumption of probiotics. Alternatively, probiotic supplements may be useful in athletes.
Efficacy of a multispecies probiotic as adjunctive therapy in generalized anxiety disorder: a double blind, randomized, placebo-controlled trial
Published in Nutritional Neuroscience, 2021
Sevda Eskandarzadeh, Mohammad Effatpanah, Kianoush Khosravi-Darani, Reza Askari, Agha Fatemeh Hosseini, Mahnaz Reisian, Shima Jazayeri
Patients were referred from a university general hospital. At first patients had been screened through GAD-7 test and the patients with the score of more than 7 were interviewed by two psychiatrists. They had a diagnosis of GAD based on DSM-V criteria and SCID-I semi-structured interview, were 18–65 years old and signed a written informed consent. Exclusion criteria were having any medical diseases including inflammatory disorders or other psychiatric diseases such as psychosis, suicidal ideation, bipolar disorder and major depressive disorder, being smoker, having drug or alcohol dependence, taking any medication or dietary supplement including probiotics, or consumption of fermented foods, such as sour cream, acidophilus milk, kefir and some cheeses during one month before the intervention, substance abuse, pregnancy, lactation or consumption of less than 80% of the capsules. Participants were also asked not to take any other supplements or medicines during the intervention. Their dietary intake also was assessed by three 24-hour dietary recall method, before and after intervention (Supplementary Table 1).