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Timing of Treatment for Craniosynostosis and Faciocraniosynostosis: A 20-Year Experience
Published in Niall MH McLeod, Peter A Brennan, 50 Landmark Papers every Oral & Maxillofacial Surgeon Should Know, 2020
The biggest changes have arisen due to the introduction of distraction osteogenesis as a treatment modality. Posterior vault distraction has become the mainstay for early surgical expansion of skull volume. This technique, pioneered by the Birmingham Craniofacial Unit, utilises distraction osteogenesis to push the posterior skull backwards, allowing for a significant increase in volume compared to fronto-orbital advancement and remodelling (FOAR).2
Limb Reconstruction
Published in Timothy W R Briggs, Jonathan Miles, William Aston, Heledd Havard, Daud TS Chou, Operative Orthopaedics, 2020
Distraction osteogenesis requires StabilityMaintenance of blood supplyA latency period (5–7 days)Appropriate rate of distraction (0.75–1 mm per day)Appropriate rhythm (frequency) of distraction (0.25 mm, 6–8 hourly)
Review of literature
Published in R. L. Mittal, Clubfoot, 2018
In part 2 of this series, Goldstein et al.45 reviewed the principals of distraction osteogenesis and discussed their indications, instrumentation, and surgical technique. Among the important contributors in this field, the name of Dr. Gavril Ilizarov stands tall.
The effect of shock waves on mineralization and regeneration of distraction zone in osteoporotic rabbits
Published in Annals of Medicine, 2023
Enes Özkan, Erman Şenel, Mehmet Cihan Bereket, Mehmet Emin Önger
Distraction osteogenesis (DO) is a generally accepted method for treating congenital and acquired deformities and inadequacies. It is based on gradually separating two bone fragments using an osteotomy to create new bone tissue [6,7]. In addition to being a long-drawn-out treatment, which is considered a disadvantage, there is a risk of stress-shielding osteopenia and osteoporosis in the bone due to the excessive load exerted by the distractors and screws [6]. There is a %38 possibility of recurrence of a fracture around the distractor or in the regeneration due to this osteoporotic condition [8]. Numerous physical or interventional methods have been analyzed to induce regeneration, including local application of growth factors, transplantation of osteoblast cell lines, local gene therapy, low-level laser therapy, and electrical and ultrasonic stimulation [6]. None of these approaches have yet been used in clinical practice. Therefore, it is critical to investigate effective non-invasive methods that might shorten the consolidation time and reduce stress-protective osteoporosis by inducing new bone formation in DO, even under poor osteogenic conditions.
Mechanical properties of the human periosteum in the mandibular ostegenesis context
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2019
J. Dallard, A. Debelmas, S. Asiri, N. Kogane, A. Picard, N. Kadlub, J. Boisson
Distraction Osteogenesis (DO) is a surgical procedure consisting in the progressive lengthening of a bone segment (1 mm/day). The technique requires the implantation of a distractor device, which daily activation is responsible for the lengthening of the bone. Distraction is widespread in the craniofacial area for the treatment of congenital malformations or acquired large bone defects (Adolhs et al. 2014). DO activation requires a transmucosal or transcutaneous rod which may be responsible for multiple adverse events and incomfort. To overcome these issues, we demonstrated recently the feasibility of distant activation with a magnetically activated device for mandibular distraction (Boisson et al. 2016). However, to develop new distraction device, one must fully understand the role of the surrounding soft tissues, especially the periosteum, and their participation in the mechanical load opposing the distraction vector.
Limb lengthening and deformity correction with externally controlled motorized intramedullary nails: evaluation of 50 consecutive lengthenings
Published in Acta Orthopaedica, 2019
Joachim Horn, Ivan Hvid, Stefan Huhnstock, Anne B Breen, Harald Steen
Distraction osteogenesis by use of an external fixator is a well-established method. To overcome problems associated with the use of external fixation, several techniques that allow early removal of the frame have been developed, including lengthening over a nail (Bost and Larsen 1956, Paley et al. 1997), lengthening and then nailing (Faber et al. 1991, Rozbruch et al. 2008), and lengthening and then plating (Harbacheuski et al. 2012). Further progress has been made by the development of mechanical (Guichet 1999, Cole et al. 2001) and externally controlled motorized intramedullary lengthening devices like the Fitbone nail (Betz et al. 1990, Baumgart et al. 1997) and the Precice nail (Kirane et al. 2014, Schiedel et al. 2014, Paley 2015).