China
Africa
Explore chapters and articles related to this topic
Adnexal Diseases
Published in Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang, Roxburgh's Common Skin Diseases, 2022
Hasan Aksoy, Jordan V. Wang, Ayşe Serap Karadağ
Ocular involvement is present in 50–60% of patients who have rosacea, which can manifest with nonspecific symptoms, such as dryness, tearing, gritty sensation, styes, blepharitis, and itching. There is no correlation between the presence of ocular involvement and the severity of skin disease. Ocular rosacea is historically underdiagnosed.
Eyelids
Published in Mostafa Khalil, Omar Kouli, The Duke Elder Exam of Ophthalmology, 2019
Omar Kouli, Mostafa Khalil, Stewart Gillan
Blepharitis is subdivided into anterior and posterior blepharitis. Anterior blepharitis: Inflammation of the skin around the base of the eyelashes and is divided into staphylococcal or seborrheic.Posterior blepharitis: Inflammation of the meibomian gland around the eyelid margins due to gland dysfunction. May be associated with ocular rosacea.
Ocular Rosacea (Subtype 4)
Published in Frank C. Powell, Jonathan Wilkin, Rosacea: Diagnosis and Management, 2008
Frank C. Powell, Jonathan Wilkin
Probably the first description of ocular rosacea was by the famous English dermatologist Willan in the early 1800’s whose handwritten note on an illustration of a patient with PPR documented the presence of ocular inflammation. Ocular rosacea may be defined as a range of changes that occur in the eye lid, eye lashes or eyes of patients with rosacea. While there are no specific or diagnostic types of ocular inflammation that occur in this condition, some findings and lesions occur commonly. Ocular changes may accompany the skin changes, precede them or follow the appearance of their appearance. Patients with papulopustular rosacea (PPR) appear to be more prone to developing ocular rosacea than those with erythematotelangiectatic rosacea (ETTR) or phymatous rosacea (PR). The duration or severity of ocular rosacea does not appear to parallel the type, duration, or severity of the skin changes, although it has been suggested that there is a correlation between the presence of ocular involvement and the tendency to flush (1). There is no laboratory or investigative test that will confirm the diagnosis of ocular rosacea.
Serum Levels of Thyroid Hormone, Vitamin B12, Vitamin D3, Folic Acid, and Ferritin in Chalazion
Published in Ocular Immunology and Inflammation, 2022
Some systemic conditions are known to be associated with chalazion. Rosacea is one of the most important chalazion-associated systemic diseases. Ocular findings, including peri-ocular erythema, telangiectasia of the eyelid margin, scarring/loss of the Meibomian gland orifices, Meibomian gland dysfunction, and conjunctivitis, are present in rosacea in about 75% of cases, and many common pathophysiological mechanisms are responsible for ocular rosacea and chalazion.10 Other systemic conditions, including gastritis, anxiety, irritable bowel syndrome, or smoking, have been reported as associated with chalazion.11 Low vitamin levels and disturbed balances of androgens during pregnancy or puberty are also known as metabolic reasons for chalazion.9,11–13 Nevertheless, association between chalazion and systemic conditions or serum parameters obtained by peripheric blood sampling is a less illuminated issue in ophthalmology practice. The aim of this study is to investigate the presence of difference in serum thyroid hormone, vitamin B12, vitamin D3, folic acid, and ferritin level abnormalities in chalazion patients and to inspire further studies to describe potential treatment and prevention strategies for chalazion.
Efficacy of Topical Ivermectin for the Treatment of Cutaneous and Ocular Rosacea
Published in Ocular Immunology and Inflammation, 2021
B. Sobolewska, Deshka Doycheva, Christoph M. Deuter, Martin Schaller, Manfred Zierhut
Rosacea is a chronic inflammatory cutaneous disease which is often overlooked due to initially readily visible and transient clinical signs such as transient erythema or flushing and/or papules and pustules.1–4 The current epidemiologic data are showing an increasing prevalence rate of the disease compared to previous reports with around 10% of the European population.56 Since ocular involvement (ocular rosacea) occurs in more than half of all rosacea patients and can be the initial manifestation of the disease, an ophthalmologist should be aware of rosacea and its treatment. The most common symptoms of ocular rosacea are unspecific and include blepharitis with lid margin telangiectasia and meibomian gland dysfunction, recurrent hordeola/chalazia, conjunctival hyperemia, dry eye, subconjunctival fibrosis and scarring, sometimes mimicking mild ocular cicatricial pemphigoid.27-11
Elevated Tear Human Neutrophil Peptides 1-3, Human Beta Defensin-2 Levels and Conjunctival Cathelicidin LL-37 Gene Expression in Ocular Rosacea
Published in Ocular Immunology and Inflammation, 2019
Nesrin Büyüktortop Gökçınar, Ayşe Anıl Karabulut, Zafer Onaran, Erhan Yumuşak, Fatma Azize Budak Yıldıran
In this study, we analyzed HNP 1–3 and hBD-2 levels in tear samples, as well as LL-37, hBD-2, and hBD-9 gene expression levels in conjunctival impression cytology samples of patients with ocular rosacea and compared the results with healthy controls. We hypothesized that increased levels of LL-37 expression played a role in the pathogenesis of ocular rosacea, similar to the cutaneous involvement. In addition to LL-37, we aimed to evaluate the status of HNP 1–3, hBD-2, and hBD-9, which were previously shown to be altered in certain inflammatory ocular surface diseases including dry eye, corneal infections, and injury.29 Ocular rosacea is known to be associated with dry eye, especially with the evaporative type.2 However, the exact mechanism in the pathogenesis of rosacea-associated ocular inflammation and dry eye is not yet fully known. We thought that HNP 1–3, hBD-2, and hBD-9 might be involved in the pathogenesis of dry eye in ocular rosacea. For this reason, we evaluated the association between these molecules and tear function tests.