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Use of silicone oil in vitreous surgery
Published in A Peyman MD Gholam, A Meffert MD Stephen, D Conway MD FACS Mandi, Chiasson Trisha, Vitreoretinal Surgical Techniques, 2019
Peter J Kertes, Gholam A Peyman
Early complications of silicone oil injection are primarily confined to the anterior segment and can be limited by preventing the anterior migration of oil. When such anterior migration is not prevented, irreversible silicone keratopathy occurs as often as 50% of the time in eyes followed for an average of 8.5 months. Corneal changes frequently present as bullous keratopathy in older patients and as band keratopathy in younger patients (Figure 20.6).28
Herpes Simplex Virus Ocular Disease
Published in Marie Studahl, Paola Cinque, Tomas Bergström, Herpes Simplex Viruses, 2017
Diffuse and chronic corneal edema (bullous keratopathy) may be the aftermath of repeated attacks of endotheliitis; it predisposes to corneal melting and corneal infection and may benefit from penetrating keratoplasty (39). Persistent trabeculitis and inflammatory response can lead to chronic glaucoma from structural damage to the trabecular meshwork. When it does not respond to medical measures, consideration should be given to glaucoma filtration surgery.
Effect of the Presence of Silicone Oil in the Anterior Chamber After Complicated Retinal Detachment Surgery on Corneal Morphology by In Vivo Confocal Microscopy
Published in Current Eye Research, 2023
Murat Kasikci, Sabahattin Sul, Huseyin Cem Simsek, Aylin Karalezli, Merve Simsek, Safak Korkmaz
The study sample included 32 eyes of 32 cases that underwent complicated pseudophakic retinal detachment surgery and had silicone oil migrated into the anterior chamber (Group 1), and 31 eyes of 31 cases that underwent complicated pseudophakic retinal detachment surgery but did not have silicone oil migration into the anterior chamber (Group 2). All cases that participated in the study were pseudophakic. All patients were chosen from pseudophakic situations in order to prevent corneal endothelial damage caused by a variety of factors. The mean age of Group 1 was 65 ± 12, and the M/F ratio was 18/14. Group 2 had a mean age of 61 ± 11 and an M/F ratio of 17/14. Postsurgical biomicroscopic examination revealed bullous keratopathy in 3 patients of Group 1, nonbullous corneal edema in 9, and pigmented keratic precipitates (KP) in the endothelium of 7 patients. On the other hand, despite the fact that silicone oil had migrated into the anterior chamber in 5 cases, the corneas of these individuals were transparent and free of edema (Table 1).
Delivering Endothelial Keratoplasty Grafts: Modern Day Transplant Devices
Published in Current Eye Research, 2022
Mohit Parekh, Vito Romano, Kareem Hassanin, Valeria Testa, Rintra Wongvisavavit, Stefano Ferrari, Colin Willoughby, Diego Ponzin, Vishal Jhanji, Namrata Sharma, Julie Daniels, Stephen B. Kaye, Sajjad Ahmad, Hannah Levis
The NS Endoserter has also been reviewed by Yokogawa et al.38 The study evaluated the use of a suture pull-through technique using NS Endoserter (NSI, Hoya Co. Ltd, Tokyo, Japan) to treat bullous keratopathy (BK). DSAEK tissues were loaded in the NSI device and pulled into the anterior chamber using a lifeline suture in six aphakic eyes. Intraoperative complications, graft dislocation, or primary graft failures were not observed. ECL at 6 months was 27%. The aim of this study was to show the efficacy of the technique for complicated eyes using the NS Endoserter device, which allowed safe insertion of DSAEK without donor tissue migration into the vitreous cavity. However, in another study,39 the outcomes of NS Endoserter were investigated for DSAEK on BK secondary to argon laser iridotomy. The donor tissue was pushed using pressure flow unlike the one described by Yokogawa et al.38 where the authors used a pull-through technique. No intraoperative or postoperative complications were observed. A mean ECL of 14% was recorded thus showing comparable results with conventional DSAEK insertion techniques.
Descemet’s Membrane Endothelial Keratoplasty with Split Corneal Grafts: The Influence of Tamponade Material and Endothelial Storage Time
Published in Seminars in Ophthalmology, 2019
Selim Genc, Beril Tulu Aygun, Fehim Esen, Yusuf Yildirim, Alper Agca
We have observed a statistically significant increase in best-corrected visual acuity, which was also consistent with the previous reports describing that DMEK improved visual acuity very rapidly.5,10,11 However, in our series both preoperative and postoperative BCVA values are relatively low compared to the previous reports.16,17 As mentioned above we had more cases with pseudophakic bullous keratopathy compared to the other reports and many of these cases referred for DMEK very late. The long-standing bullous keratopathy further damaged the stroma of these patients, limiting the potential of final improvement in visual acuity. When we checked the database of our eye bank, our DMEK rate was around 35% among bullous keratopathy cases because of these stromal pathologies, while our DMEK rate was around 80% among FED cases, which did not have a stromal pathology. Despite these challenges we still believe that DMEK was a better choice for these patients because of a lower risk of corneal rejection9 and induction of irregular astigmatism.18