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Interstitial, Cornual, and Angular Pregnancy
Published in Botros Rizk, A. Mostafa Borahay, Abdel Maguid Ramzy, Clinical Diagnosis and Management of Gynecologic Emergencies, 2020
An interstitial pregnancy is an uncommon type of ectopic pregnancy that results from embryonic implantation in the myometrium surrounding the interstitial part of the fallopian tube and includes 2% to 4% of all ectopic pregnancies [3]. Wang et al. found the incidence of interstitial pregnancy after in vitro fertilization (IVF)/embryo transfer (ET) to be 2.3%, with slightly higher rates after fresh ET (2.6%) than after frozen ET (2.2%) [4]. A higher incidence of interstitial pregnancy with IVF is likely due to the high rate of tubal infertility and undergoing procedures such as salpingectomy before IVF [4]. A cornual pregnancy is defined as implantation of the embryo in the fundal intrauterine portion of the anomalous bicornuate or septate uterus. Angular pregnancy is defined as implantation of the embryo into the lateral superior angle of the uterine cavity [3].
Examination C
Published in Aalia Khan, Ramsey Jabbour, Almas Rehman, The New DRCOG Examination, 2017
Aalia Khan, Ramsey Jabbour, Almas Rehman
Blood loss may be dark or fresh; other symptoms of ectopic pregnancy include shoulder tip pain as well as pain on urination or defecation, and fainting. Always think of ectopic if abdominal pain +/-bleeding. A cornual pregnancy is where the embryo implants into the interstitial rather than the extra-uterine part of the tube. The mortality rate is 1 in 50 compared to 1 in 3000 with other ectopic pregnancies as bleeding can be sudden and catastrophic.
Study on diagnosis and management strategies on heterotopic pregnancy: a retrospective study
Published in Journal of Obstetrics and Gynaecology, 2023
Yan Zhang, Xiujuan Chen, Yuan Lin, Chengying Lian, Xiumei Xiong
HP was diagnosed mainly based on TVS examination (first TVS), the serum β-HCG level and the history clinical manifestations used as a reference. Biochemical pregnancy was defined as a transient rise in β-hCG that subsequently declined, without evidence of a gestational sac inutero. IUP was defined as a yolk sac and/or foetal pole in an intrauterine sac, regardless of cardiac activity detecting by TVS. The diagnosis of tubal HP (excluded interstitial) was suspected when an IUP was accompanied with a gestational sac with or without cardiac activity, an empty extrauterine sac with a hyperechoic ring or a heterogeneous adnexal mass in an extrauterine sac (Condous et al. 2005). The differential diagnosis of cornual pregnancy and tubal interstitial pregnancy was based on as follows: the gestational sac location, inner/lateral side of the uterine horn, complete muscular layer around, connecting with the endometrial line, and inside/outside the ligament during the operation.
Hysteroscopic diagnosis of an intrauterine pregnancy mimicking an interstitial pregnancy on ultrasound
Published in Journal of Obstetrics and Gynaecology, 2021
Yu-Hung Lin, Lee-Wen Huang, Jiann-Loung Hwang, I-Fang Yang, Ting-Chi Huang
Interstitial or cornual pregnancy is a rare type of ectopic pregnancy and accounts for 2–4% of ectopic pregnancy (Damario and Rock 2008). Because of the abundant blood supply at the cornua, rupture of such a pregnancy can lead to life-threatening haemorrhage, with a mortality rate of 2–2.5% (Tulandi and Al-Jaroudi 2004). Thus, early diagnosis is important. However, differentiating between an eccentric intrauterine pregnancy and an interstitial pregnancy is often difficult. Even with the advances of ultrasonography, the misdiagnosis rate can be as high as 41.7% (Chan et al. 2003). We report here a case of suspected interstitial pregnancy which was diagnosed as an eccentrically located intrauterine pregnancy by hysteroscopy. To the best of our knowledge, this is also the first report of early gestation visualised by hysteroscopy.
Laparoscopic management of a cornual pregnancy following failed methotrexate treatment: case report and review of literature
Published in Gynecological Endocrinology, 2020
Raffaele Tinelli, Massimo Stomati, Daniela Surico, Ettore Cicinelli, Giuseppe Trojano, Stefano Angioni
In this case report we describe a rare case of a singleton 8-week cornual pregnancy (CP), unsuccessfully managed by chemotherapy, treated by laparoscopic incision of the uterine wall, removal of the ectopic pregnancy and suturing of the uterine site with interrupted sutures.