China
Africa
Explore chapters and articles related to this topic
Historical Perspectives on Psychoneuroimmunology
Published in Herman Friedman, Thomas W. Klein, Andrea L. Friedman, Psychoneuroimmunology, Stress, and Infection, 2020
Psychoneuroimmunology refers, most simply, to the study of the interactions among behavioral, neural and endocrine (or neuroendocrine), and immunological processes of adaptation. Its central premise is that homeostasis is an integrated process involving interactions among the nervous, endocrine and immune systems. The term was first used in 1980, in my presidential address to the American Psychosomatic Society.1 Its most conspicuous use was as the title of an edited volume2 which one reviewer referred to prophetically as “The signature volume of a new field of research.” This first volume was an attempt to bring together emerging research suggesting a relationship between the brain and the immune system. Traditionally, however, the immune system has been considered an autonomous agency of defense - a system of bodily defenses regulated by cellular interactions that are independent of neural influences. Besides, there were no known connections between the brain and the immune system. To be sure, it was known that hormones or at least adrenal hormones could influence immunity; some investigators were aware that brain lesions could influence immune responses; and it was also known or, at least, suspected that emotional states were associated with the development or progression of diseases related to the immune system. Few scientists at that time, however, took such observations too seriously. After all, there were no mechanistic explanations for how such things could happen.
The role of psychoneuroimmunology in oncology and palliative care education
Published in Lorna Foyle, Janis Hostad, Delivering Cancer and Palliative Care Education, 2018
The facts of psychoneuroimmunology have far-reaching implications for basic biological sciences, academic and clinical medicine and the effectiveness of healthcare (Kiecolt-Glaser et al. 2002b). Holistic, patient-centred care advocated by modern healthcare providers and receivers – shared decision making and ‘relationship-centred care’ (Tresolini 1994) – is supported by psychoneuroimmunology. It is then a natural extrapolation to envisage psychoneuroimmunology as an underpinning philosophy of healthcare from health promotion through to terminal care and bereavement support.
Holistic view of health and illness
Published in Mabel Aghadiuno, Christopher Dowrick, Soul Matters – The Spiritual Dimension within Healthcare, 2017
The idea of stress inducing changes in the endocrine and immunology systems has existed for several years. It is called psychoneuroimmunology and involves many disciplines – psychiatry, psychology, neurology, internal medicine, endocrinology and immunology being some examples. It is concerned with interactions between the brain (mind/behaviour) and the immune system and the clinical effects produced. Robert Ader first coined the term in the 1970s. The field has grown so much in recent decades that at the time of writing, a major tome by Ader with over thirteen hundred pages on the subject has reached its fourth edition.22
Age as a moderator for the association between depression and self-rated health among cancer survivors: a U.S. based population study
Published in Journal of Psychosocial Oncology, 2023
Anao Zhang, Kaipeng Wang, Chiara Acquati, Aarti Kamat, Emily Walling
For cancer survivors, depression negatively impacts SRH through primarily two pathways: (1) intermediary patient-reported outcomes that consequently influence cancer survivors’ SRH, and (2) the nervous and immune system, a field known as psychoneuroimmunology, which explicitly connects psychosocial stress with immunity through neuroendocrine pathways.15 First, depression has been consistently linked with sleep disturbance, social isolation, poor health behavior for disease management, and chronic fatigue among other patient-reported outcomes.12,16 Low ratings on these important patient-reported outcomes among cancer survivors would, in turn, lead to poor evaluation of their health status, resulting in a negative relationship between depression and cancer survivors’ SRH. Additionally, accordingly to the theory of psychoneuroimmunology, individuals with depression experience chronic stress and the central nerve system releases pro-inflammatory hormones, which consequently compromises individuals’ immune system.17 As individuals with depression start to experience manifesting physical symptoms due to compromised immunity, they are likely to report poor SRH. In summary, depression is a well-established correlate to SRH among cancer survivors, which is worth clinical and research attention.
Memorial to Daniel P. Brown, Ph.D., ABPH
Published in American Journal of Clinical Hypnosis, 2022
In the 1980s Dr. Brown was the Director of Training and then Chief Psychologist at The Cambridge Hospital. There, he helped develop and gain accreditation for an APA-approved clinical psychology internship and post-doctoral training program. His vision was to provide the best young talent in psychology the opportunity to work with a disenfranchised inner city chronic mental health population, which included intensive developmentally informed psychotherapy for patients with major mental illness and complex trauma disorders. His program included intensive multicultural and bilingual mental health training. At the Cambridge Hospital, he developed and directed the Behavioral Medicine Program, a joint venture between psychiatry and primary care medicine. His book Hypnosis and Behavioral Medicine represents the clinical approaches developed in that program. He developed a special interest in psychoneuroimmunology and the psychosocial treatment of immune disorders. As a result he developed a joint exchange between the Beijing College of Traditional Chinese Medicine and The Cambridge Hospital for dissemination of research findings on approaches to treating immune-related disorders in TCM and behavioral medicine.
Pain and affective distress in arthritis: relationship to immunity and inflammation
Published in Expert Review of Clinical Immunology, 2019
Manfred Harth, Warren R. Nielson
The relationship between the endocrine, immune and central nervous systems has been the subject of burgeoning research over the past two decades and has led to the emergence of the field of psychoneuroimmunology [31]. In RA, evidence is beginning to accumulate in support of the view that psychological and social stressors can trigger the disease process. For example, women with Post-Traumatic Stress Disorder (PTSD) appear to have an increased risk of developing RA. Lee et al. studied 54,224 nurses (the Nurses’ Health Study) who were screened for PTSD symptomatology and were followed from 1989 to 2011 [32]. After adjusting for age, race, socioeconomic status and smoking those with ≥4 PTSD symptoms had a significantly greater risk (Hazard ratio: 1.76) of developing RA. One twin study [33], and longitudinal data from military veterans [34] also suggest that PTSD may precipitate RA. Low socioeconomic status has also been found to be associated with worse outcomes of inflammatory polyarthritis [35], although the physiological mechanisms underlying this finding have not been delineated.