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Complex lower extremity revascularization
Published in Peter A. Schneider, Endovascular Skills: Guidewire and Catheter Skills for Endovascular Surgery, 2019
Another debulking option is excimer laser-assisted angioplasty. The excimer laser is useful for recanalizing occlusions and burring holes through occlusions that will assist in guidewire placement using a step-by-step approach with the wire. The excimer laser is also useful in debulking superficial femoral, popliteal, and tibial artery lesions. One major advantage of the excimer laser over the atherectomy device is that the excimer laser is a bit faster and it can also be used to dissolve some emboli if they should occur during the process of debulking. The laser may be passed more than once at progressively higher power levels, but it achieves a proscribed diameter of the artery, based on the size of the catheter and whether a turbo booster is used.
Basic science, investigations and lasers
Published in Mostafa Khalil, Omar Kouli, The Duke Elder Exam of Ophthalmology, 2019
Tarek Khalil, Bilal Ibrahim, Stewart Gillan, Obaid Kousha
These work by breaking chemical bonds that hold tissue together using ultraviolet light, in a process called photoablation. An excimer laser is a laser that causes photoablation and has important uses in refractive surgery: Photorefractive keratectomy (PRK): Corneal epithelium is first removed, then laser ablation is used to reshape the cornea.Laser-assisted in situ keratomileusis (LASIK): A corneal flap is created; the stroma is then ablated (to reshape the cornea) and the flap is replaced.Laser epithelial keratomileusis (LASEK): The corneal epithelium is peeled using 20% ethanol, laser ablation is performed and the epithelium is replaced.
Current Recommendations for the Treatment of Psoriasis
Published in Siba P. Raychaudhuri, Smriti K. Raychaudhuri, Debasis Bagchi, Psoriasis and Psoriatic Arthritis, 2017
Excimer laser is a newer high-energy 308 nm ultraviolet therapy that localizes treatment to involved skin only. This targeted therapy allows higher doses of UVB and has been shown to require fewer treatments than conventional phototherapy.55,56 The main side effects include erythema, blistering, and hyperpigmentation of treated areas, which resolved with discontinuation of treatment.
Evidence-based clinical practice guidelines for the management of psoriasis: systematic review, critical appraisal, and quality assessment with the AGREE II instrument
Published in Journal of Dermatological Treatment, 2022
Mohamed Ali Babiker Mohamed, Ahmed M. El-Malky, Wael Ahmed Abdelwahab Abdelkarim, Mohamed Abdulmonem Salih Aabdeen, Tarig Hassan Elobid Ahmed, Hassan H. H. Sarsour, Munirah Mohammed Mosa, Yasser S. Amer, Abdulrahman Ali M. Khormi, Abdulmajeed Alajlan
Management of psoriasis aims at stopping skin cells to over grow, remove the scales and crusts, however, treatment modalities varied through the time to pass via many development stages which was approved by international agencies and scientific communities (6,7). Topical therapy; corticosteroids, vitamin D analogs, retinoids, calcineurin inhibitors, salicylic acid, coal tar, anthralin, and Goeckerman therapy. Light therapy; sunlight, ultraviolet radiation, and Excimer laser. Oral or injected medications; Methotrexate, Cyclosporine, and biologics (8). Various treatment modalities for managing psoriasis have been established by societies, academies, and organizations. However, inconsistencies have led to confusion and discrepancies among schools and care givers (9,10). This situation has motivated the scientific community to establish guidelines for reducing variations in treatment, and thus, eliminating the possibility of errors. Currently, there is no national Clinical Practice Guideline (CPG) in Saudi Arabia for the care of patients with psoriasis (11–13).
Evaluation of the Difference between Predicted and Measured Central Corneal Thickness Reduction after SMILE and Femtosecond Laser-assisted LASIK for Myopia
Published in Current Eye Research, 2021
Currently, there are many types of excimer lasers in clinical practice. Clinicians performing excimer laser surgery on different lasers should understand the relationship between expected and measured ablation depth for different machines to increase the refractive predictability of the laser. In our study, the Aspheric Smart Ablation profile of MEL 80 platform tends to systematically overestimate the measured CCT reduction, which can be subtracted when calculating the residual stromal thickness. For SMILE surgery, the presence of the cap may lead to different biomechanical distributions, which may affect the achieved lenticule thickness and thus affect refractive correction. Further studies with larger population are still needed to confirm the difference between the estimated and measured CCT reduction of SMILE with different cap thickness.
Meta-analysis of 308-nm excimer laser therapy for alopecia areata
Published in Journal of Dermatological Treatment, 2021
In addition to lasers, the 308-nm excimer lamp was also investigated for AA treatment. The excimer lamp is similar to the excimer laser device differing in that the lamp emits incoherent light and may require a longer duration but like the laser maintains the ability to target specific lesions. In practice, the 308-nm excimer lamp and laser have demonstrated similar efficacy in treating other autoimmune diseases such as vitiligo (18) and psoriasis (19). Therefore, four uncontrolled trials/case studies tested 308-nm light for efficacy (20–23). All studies recommended the use of 308-nm light therapy for AA, including recalcitrant AA and AU. In a trial of 11 patients with resistant AU, four were considered to have a good response (20). Regrowth did not correlate with disease duration or history of atopic dermatitis. In a second trial, three out of eight patients observed regrowth, including one case of AU and two AA (21). In a third trial, 14 out of 16 patients had regrowth with 10 being more than 50% (23). In a case series of three patients with AA resistant to conventional treatment, all resulted in clinical improvement (22). Adverse events included erythema, hyperpigmentation and mild itching.