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Meta-Analyses with Individual Patient-Level Data versus Summary Statistics
Published in Ding-Geng (Din) Chen, Karl E. Peace, Applied Meta-Analysis with R and Stata, 2021
Ding-Geng (Din) Chen, Karl E. Peace
With this model, the estimated between-study variance is 0.935 and within-study variance is 69.032, which is much larger than the between-study variance. We calculate the intraclass correlation (i.e., ICC) as: > # Calculate ICC> ICC.HAMD = 0.935/(0.935+69.032)> # Print the ICC> ICC.HAMD [1] 0.0134
Repeated Measurements and Accounting for Change
Published in Mitchell G. Maltenfort, Camilo Restrepo, Antonia F. Chen, Statistical Reasoning for Surgeons, 2020
Mitchell G. Maltenfort, Camilo Restrepo, Antonia F. Chen
Information comes out of the model in terms of the potential contribution of each specific level and the variance of the associated distribution. The intraclass correlation coefficient is the fraction of variation in the outcome that can be attributed to the random effect; if the residual error is small compared to the random effect, the intraclass correlation coefficient will approach 1.0.
Ultrasonographic Monitoring of Follicle Growth in Controlled Ovarian Hyperstimulation
Published in Arianna D'Angelo, Nazar N. Amso, Ultrasound in Assisted Reproduction and Early Pregnancy, 2020
Arredondo et al. [22] carried out a study to determine the intra- and interobserver reproducibility of ovarian follicle diameter measurements in natural menstrual cycles. Two blinded observers each calculated follicle diameter measurements on 70 patients. The results showed that there was excellent correlation: intraobserver correlation coefficient for both observers was 0.99, and the interobserver correlation coefficient was 0.98. It was concluded that the reproducibility of ovarian follicle diameter measurements was clinically acceptable. Farrell et al. [23] investigated the reliability and validity of 2D ultrasound volumetric measurements using balloon models. Thirty different sets of ultrasound images were obtained from 15 water-filled balloons with volumes ranging from 19 to 697 mL. Two observers who were blinded to the true volumes of the balloons performed the measurements independently. The intraclass correlation coefficient was used to assess the intra- and interobserver reliability. Results showed the intraclass correlation coefficient ranged from 0.992 to 0.998 for reliability and validity, whereas the Pearson correlation coefficient for validity was 0.996. In conclusion, high levels of reliability and validity were obtained for ultrasound balloon volume measurements.
Below-elbow cast sufficient for treatment of minimally displaced metaphyseal both-bone fractures of the distal forearm in children: long-term results of a randomized controlled multicenter trial
Published in Acta Orthopaedica, 2021
Linde Musters, Leon W Diederix, Kasper C Roth, Pim P Edomskis, Gerald A Kraan, Jan H Allema, Max Reijman, Joost W Colaris
To evaluate whether the included patients in the current study are representative of the total initial study population of 66 patients, we compared the baseline characteristics, functional outcome, and complications at short-term follow-up (7 months) between the included patients versus those lost to follow-up. Long-term results of primary and secondary outcome measures of the 2 treatment groups (AEC vs. BEC) were compared. Differences were analyzed using 1-way ANOVA to correct for multiple comparisons. Results are presented as mean SD or 95% confidence interval (CI). To assess the inter-rater reproducibility of radiographic assessment 2 authors (PE and LD) measured angulations of the radius and ulna of 25 cases (at cast removal and at final follow-up). Intra-class correlation coefficient was calculated. Statistical analyses were performed using IBM SPSS Statistics version 23.
Psychological factors are more strongly associated with pain than radiographic severity in non-invasively treated first carpometacarpal osteoarthritis
Published in Disability and Rehabilitation, 2021
Lisa Hoogendam, Mark J. W. van der Oest, Jonathan Tsehaie, Robbert M. Wouters, Guus M. Vermeulen, Harm P. Slijper, Ruud W. Selles, Jarry T. Porsius
The patients’ records were searched for X-rays of the first carpometacarpal joint. If multiple X-rays were present, we selected the X-ray in which both the CMC-1 joint and the scaphotrapeziotrapezoid joint (STT) were most clearly visible. The Eaton-Glickel classification [32] ranges from stage I to stage IV. Stage III is defined as excessive CMC-1 degeneration and subluxation. Stage IV is defined as stage III with additional presence of STT OA. According to this classification, presence of STT OA indicates the most advanced stage of structural damage. Therefore, we used this feature as indication of radiographic severity of disease. The first 100 X-rays were independently scored by both a European Board-certified hand surgeon (G. V.) and a junior scientist (L.H.). The Intraclass Correlation Coefficient was 0.58 (95% CI 0.49–0.65). This is in agreement with the study by Dela Rosa et al. [33], who reported fair to moderate inter-observer agreement for the Eaton-Glickel classification, with similar agreement rates for stage I, III and IV. The scores of the junior scientist were used for all patients. Patients without an X-ray of the CMC-1 joint were excluded.
Heart aging when near vision difficulty begins
Published in The Aging Male, 2020
Şahbender Koç, Sadettin Selçuk Baysal
Diastolic dysfunction was evaluated according to 2016 echocardiography-diastolic dysfunction guidelines [17]. The following cutoff values were used to identify elevated left atrium pressure: mitral anulus lateral e’ velocity <10 cm/s, average E/e’ ratio >14, left atrium maximum volume index >34 ml/m2, and peak tricuspid regurgitation peak velocity >2.8 m/s. If fewer than two of four values were below the cutoff, the cutoffs were accepted as normal diastolic function. However, if two of four values were below the cutoffs, the cutoffs were accepted as indeterminate, and if more than two of four values were above the cutoffs, the cutoffs were accepted as diastolic dysfunction. Images were analyzed by two cardiologists unaware of the other cardiologist’s clinical data. The average intraclass correlation was 0.86 (CI: 0.84–0.92) and the interclass correlation was 0.84 (CI: 0.82–0.90).