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Published in Nirmal Raj Gopinathan, Clinical Orthopedic Examination of a Child, 2021
Prateek Behera, Karthick Rangasamy, Nirmal Raj Gopinathan
Children with arthrogryposis have difficulty in ambulation. Most patients with amyoplasia are unable to walk. Those with distal arthrogryposis can ambulate but have a lower activity level and walk slowly with small steps.
Reproductive and Developmental Toxicity Studies by Cutaneous Administration
Published in Rhoda G. M. Wang, James B. Knaak, Howard I. Maibach, Health Risk Assessment, 2017
Rochelle W. Tyl, Raymond G. York, James L. Schardein
Malathion is an organophosphorus insecticide that is not particularly well absorbed through the skin.171 A case of amyoplasia congenita-like condition is reported from maternal malathion exposure.172 During the 11th and 12th week after conception, the mother washed her hair repeatedly with large amounts of a hair lotion containing 0.5% malathion for control of lice. The authors speculated that the repeated application and longstanding wetness of the hair on the skin may have resulted in sufficient malathion uptake to result in the severely malformed baby.
Neuromuscular disorders
Published in Ashley W. Blom, David Warwick, Michael R. Whitehouse, Apley and Solomon’s System of Orthopaedics and Trauma, 2017
In the most common form, arthrogryposis multiplex congenita (nowadays known as amyoplasia), all joints of the upper and lower limbs are involved including the spine. In others, restriction is more minor and predominantly affects the distal extremities.
Physical functioning and activities of daily living in adults with amyoplasia, the most common form of arthrogryposis. A cross-sectional study
Published in Disability and Rehabilitation, 2018
Unni Steen, Lena Lande Wekre, Nina Køpke Vøllestad
Amyoplasia is the most common type of AMC and represents about one-third of all cases [5]. Amyoplasia (A = no; myo = muscle; plasia = growth) is characterized by typical deformities of the joints as shown in Figure 1; internally rotated and adducted shoulders, extended elbows, pronated forearms, flexed wrists, and camptodactyly. The hands may be cupped and the thumbs positioned in the palm. In the lower limbs, the hips may be dislocated, the knees extended, but can also be flexed, and the feet do often have severe equinovarus contractures. The contractures are usually symmetric [5].