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Order Piccovirales
Published in Paul Pumpens, Peter Pushko, Philippe Le Mercier, Virus-Like Particles, 2022
Paul Pumpens, Peter Pushko, Philippe Le Mercier
Human parvovirus 4 (PARV4) of the Primate tetraparvovirus 1 species was identified in 2005 in nuclease-digested plasma from patients with acute viral infection syndrome and detected, with widely varying frequencies, in plasma samples worldwide, but its clinical associations remained uncertain (Cotmore et al. 2019).
Human Bocavirus
Published in Dongyou Liu, Handbook of Foodborne Diseases, 2018
José Luiz Proença-Módena, Guilherme Paier Milanez, Eurico Arruda
HBoV is a member of the family Parvoviridae, which is divided into two subfamilies according to the primary host specificities. While the subfamily Densovirinae comprises invertebrate/arthropod-infecting viruses, the subfamily Parvovirinae covers agents that infect vertebrates. The subfamily Parvovirinae currently includes eight genera: Amdoparvovirus, Aveparvovirus, Bocaparvovirus, Copiparvovirus, Dependoparvovirus, Erythroparvovirus, Protoparvovirus, and Tetraparvovirus (Figure 8.1) [9].
The clinical use of parvovirus B19 assays: recent advances
Published in Expert Review of Molecular Diagnostics, 2018
Viruses adapted to the human host are found in the genera Dependoparvovirus (Adeno-Associated Viruses, AAV), Erythroparvovirus (B19V), Bocaparvovirus (HBoV1-4), Tetraparvovirus (PARV4). While AAV viruses are considered non-pathogenic and have been exploited as transduction viral vectors, the others possess a pathogenic potential that prompts for the development of diagnostic molecular testing in a clinical setting. B19V is a widely circulating virus implicated in a complex relationship with the host, and can be considered the most relevant human pathogenic virus in the family, posing the necessity of diagnostic awareness and appropriateness. The aim of this review is to present the more recent contributions to our knowledge on the course of virus infection, on its pathogenetic mechanisms, and on the appropriate molecular diagnostic methods.