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The Musculoskeletal System and Its Disorders
Published in Walter F. Stanaszek, Mary J. Stanaszek, Robert J. Holt, Steven Strauss, Understanding Medical Terms, 2020
Walter F. Stanaszek, Mary J. Stanaszek, Robert J. Holt, Steven Strauss
Disorders of the tendons include tendonitis, which is an inflammation of the tendon and tendon sheath, usually from a sports injury or strain. It occurs most often in the shoulder area, hamstring, or calcaneal tendon. Tenniselbow is a term that refers to epicondylitis or inflammation of the tendon fibers or ligaments of the elbow joint.
Intra-articular and local soft-tissue injections
Published in Harald Breivik, William I Campbell, Michael K Nicholas, Clinical Pain Management, 2008
Michael Shipley, Vanessa Morris
Lateral epicondylitis or “tennis elbow” is an enthesitis causing pain at the insertion of the common extensor tendon at the lateral epicondyle and in the proximal forearm. It often resolves with rest. The lateral epicondyle is tender. Making a fist and dorsiflexing against resistance typically worsens the pain.
Occupational Medicine for the Pain Practitioner
Published in Mark V. Boswell, B. Eliot Cole, Weiner's Pain Management, 2005
Epicondylitis is a tendon inflammation at the elbow that is caused by repetitive motion of the wrist. De Quervain’s tenosynovitis is an inflammation of the abductor pollicis longus and extensor pollicis brevis tendons of the thumb.
Mechanism of Action of Mesenchymal Stem Cells (MSCs): impact of delivery method
Published in Expert Opinion on Biological Therapy, 2022
Luiza L. Bagno, Alessandro G. Salerno, Wayne Balkan, Joshua M. Hare
MSCs can not only differentiate into tendon cells (tenocytes), but also modulate inflammation and tissue healing [136]. Several clinical trials investigating the use of MSCs for tendon healing are ongoing (NCT03688308, NCT01788683, NCT02484950, NCT03449082, NCT03279796, NCT03752827, NCT03454737) [136]. Six patients suffering from chronic epicondylitis were treated with local allogenic AD-MSCs injections. After 52 weeks, the visual analogic scale (VAS) and the modified Mayo Clinic Performance Index (mMCPI) were decreased by 52%, and increased by 26.6%, respectively, and on ultrasound examination, a reduction in defect areas was observed [137]. Subjects with rotator cuff tears (RCT) who did not respond to physical therapy for at least 6 weeks were randomly assigned to receive a single local injection of, on average, 11.4 × 106 autologous adipose-derived regenerative cells UA-ADRCs or corticosteroid injections. ADMSCs were safe and led to improved shoulder function without adverse effects at 12-month follow-up [138].
Platelet-rich plasma therapy ensures pain reduction in the management of lateral epicondylitis – a PRISMA-compliant network meta-analysis of randomized controlled trials
Published in Expert Opinion on Biological Therapy, 2022
Sathish Muthu, Sandeep Patel, Ashwin Gobbur, Sandesh C Patil, Karthikav Hathwar Ks, Vijendra Yadav, Madhan Jeyaraman
Lateral epicondylitis (LE) commonly known as tennis elbow, is one of the common musculoskeletal conditions affecting middle-aged patients. Although the disease has a self-remitting course ranging from 12 to 18 months, the symptoms may remain persistent and refractory to a conservative line of management treatment in many patients. Apart from rest and physiotherapy, many treatment modalities, such as local injection of corticosteroid, autologous blood, local corticosteroids, and platelet-rich plasma, are in use with some benefits. Modalities such as laser therapy, open and arthroscopic surgeries were also being tried in its management.
Immediate effects of counterforce brace with and without vibration on pain, muscle strength and range of motion in participants with lateral epicondylitis. A pilot study
Published in Assistive Technology, 2022
Forough Dehghani, Hassan Saeedi, Alireza Khaghani, Masumeh Bagherzadeh Cham
Lateral epicondylitis (tennis elbow) is a common soft tissue lesion caused by damage to the extensor muscles of the wrist upon overuse (Chumbley et al., 2000). This disorder is characterized by pain and tenderness at the lateral epicondyle of the elbow. The extensor tendons of the wrist, especially the extensor carpi radialis brevis tendon, contract at the site of attachment to the humerus due to a series of specific sports activities such as tennis or repetitive occupations which cause stretching and as a result, pain, and inflammation (Kraushaar & Nirschl, 1999; Shiri & Viikari-Juntura, 2011).