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Oesophageal Disorders in Children
Published in John C Watkinson, Raymond W Clarke, Christopher P Aldren, Doris-Eva Bamiou, Raymond W Clarke, Richard M Irving, Haytham Kubba, Shakeel R Saeed, Paediatrics, The Ear, Skull Base, 2018
The diagnosis of an oesophageal web causing complete obstruction by failure to pass an oro- or nasogastric tube necessitates surgical intervention. The perforate or crescentic membrane usually presents later in life and can be identified on a contrast swallow examination or at upper gastrointestinal endoscopy.24
Pharynx, Larynx and Neck
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
Prolonged iron deficiency anaemia may lead to dysphagia, particularly in middle-aged women. In addition, they may have koilonychia, cheilosis and angular stomatitis together with lassitude and poor exercise tolerance. The dysphagia is caused by a postcricoid or upper oesophageal web and these patients have a higher incidence of postcricoid malignancy. The syndrome is associated with the names of Plummer and Vinson, Paterson and Brown Kelly.
The Association between Meibomian Gland Atrophy and Corneal Subbasal Nerve Loss in Patients with Chronic Ocular Graft-versus-host Disease
Published in Current Eye Research, 2021
Ozlem Dikmetas, Sibel Kocabeyoglu, Mehmet Cem Mocan
This was a cross-sectional study conducted in a single tertiary referral academic center. The study was approved by the Institutional Review Board (IRB approval: GO 20/163 2020/04-34) and adhered to the tenets of the Declaration of Helsinki. The study cohort consisted of adult patients who had undergone allo-HSCT and were diagnosed as having DED in the presence of systemic GVHD. The diagnosis of systemic and ocular GVHD was made in accordance with the 2014 National Institutes of Health (NIH) consensus by the treating hematologist and ophthalmologist, respectively.24 At least one diagnostic clinical sign of GVHD (i.e. poikiloderma or esophageal web) or the presence of at least one distinctive manifestation (keratoconjunctivitis sicca) confirmed by biopsy or other relevant tests (i.e. Schirmer I test) in the same or another organ had to be present for the diagnosis of GVHD.25 Inclusion criteria included patients >18 years of age, presence of DED, and history of a stable systemic clinical course following allo-HSCT. Exclusion criteria included prior history of intraocular or corneal surgery and ocular trauma, preexisting DED prior to HSCT, previous history of contact lens wear, and co-existing corneal disease.
Esophageal foreign bodies in adults: systematic review of the literature
Published in Scandinavian Journal of Gastroenterology, 2018
Alberto Aiolfi, Davide Ferrari, Carlo Galdino Riva, Francesco Toti, Gianluca Bonitta, Luigi Bonavina
An underlying esophageal disorder was diagnosed in 25.7% of the patients. The most commonly associated disorders were stricture (33.9%), hiatus hernia (20.2%) and esophageal web or Schatzki ring (17.1%). Eosinophilic esophagitis was diagnosed at the time of presentation in 9.5% of patients. However, a population-based study showed that eosinophilic esophagitis can be the cause of food bolus impaction in up to 16% of patients; this data may still be underestimated because biopsies are not routinely taken in these patients [63]. In addition, the presence of an esophageal web may be part of the spectrum of eosinophilic esophagitis. Despite the removal of food bolus is successful in 98% of patients at first endoscopy, recurrence was most commonly observed in patients with eosinophilic esophagitis [63].