Hyperosmolar syndrome

Hyperosmolar syndrome is a medical condition characterized by high levels of glucose in the blood and severe dehydration, but without significant ketoacidosis. Diagnostic criteria for hyperglycemic hyperosmolar syndrome (HHS) include a serum glucose concentration of over 600 mg/dL, a serum osmolality of over 330 mOsm/kg, and the absence of significant ketosis and acidosis. It is also referred to as hyperglycemic hyperosmolar syndrome.From: Insulin Therapy [2019], Hyperosmolar hyperglycemic syndrome in a young boy [2019], Essentials of Pathophysiology for Pharmacy [2019]

The patient with acute endocrine problems

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Published in Peate Ian, Dutton Helen, Acute Nursing Care, 2020

Muili Lawal

Diabetes emergencies are either due to hypoglycaemic or hyperglycaemic episodes, and the most common problems are: Hypoglycaemia.Hyperglycaemia: Diabetic ketoacidosis (DKA).Hyperglycaemic hyperosmolar syndrome (HHS). Euglycemic diabetic ketoacidosis.

Hyperosmolar hyperglycemic syndrome in a young boy

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Published in Baylor University Medical Center Proceedings, 2019

Archana Reddy, Leland Finley, Shawn Horrall

Diagnostic features of hyperglycemic hyperosmolar syndrome (HHS) include a serum glucose concentration of >600 mg/dL, a serum osmolality of >330 mOsm/kg, and the absence of significant ketosis and acidosis. HHS is associated with a high mortality rate and must be addressed and monitored adequately.1 Children diagnosed with HHS are candidates for admission to intensive care units for frequent reassessment, because it is suggested that the pediatric population is at greater risk of cerebral edema secondary to rapid reduction in glucose levels.1–3

Hyperosmolar syndrome

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The patient with acute endocrine problems

Hyperosmolar hyperglycemic syndrome in a young boy