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The Scientific Revolution
Published in Scott M. Jackson, Skin Disease and the History of Dermatology, 2023
Writing in the 1770s, Plenck (see Chapter 10) called the condition crinones and referred to the lesions as setae (Latin for bristles), noting that they sometimes resembled worms or comedones (blackheads and whiteheads). Other writers discussed the excessive swaddling of the infants as contributing to the eruption of the lesions. We know today that such swaddling can lead to “prickly heat” (miliaria). The above descriptions indicate to the present author that the spots Browne and others claimed were worms or hairs were either a form of keratosis pilaris, infantile acne (blackheads, when expressed, can have a vermiculate appearance), heat bumps (miliaria), trichostasis spinulosa, or folliculitis. The primitive microscopists of the seventeenth century may also have been looking at clothing fibers that are commonly seen under the microscope along with skin scrapings. The physicians and surgeons, influenced by both superstitions as well as valid reports of helminthic disease in a growing medical literature, could have fostered misinterpretation of the morgellons as a parasitic disease.
Cutaneous Cysts
Published in Omar P. Sangueza, Sara Moradi Tuchayi, Parisa Mansoori, Saleha A. Aldawsari, Amir Al-Dabagh, Amany A. Fathaddin, Steven R. Feldman, Dermatopathology Primer of Cutaneous Tumors, 2015
Trichostasis spinulosa: Clinically unapparentPlugged follicle opens to surface with numerous vellus hairsNot a cyst
A novel case of eruptive vellus hair cysts arising during radiation therapy and a brief review of the literature
Published in Acta Oncologica, 2023
Ahava Muskat, Neda Shokrian, Yana Kost, Pooja Srivastava, Bijal Amin, Beth N. McLellan
Regarding the clinical course of EVHC, 86% of cases presented asymptomatically, while 14% reported associated symptoms, primarily pruritus [2,18,22,25,26,30,31,40,41,45,47–50]. Upon physical exam, EVHC most commonly appeared as multiple, discrete, dome-shaped, hyper-pigmented or flesh-colored, soft, or cystic papules. The most commonly considered differential diagnoses reported were keratosis pilaris (11.6%) [24,45,51–53], acneiform eruptions (10.7%) [45,52,53], perforating dermatoses (10.7%) [45,52,53], folliculitis (9.1%) [45], and acne vulgaris (5.0%) [2,25,34,54,55]. 6.6% of cases reported a potential trigger for EVHC. The proposed triggers included scratching/mechanical trauma (n = 4) [55–58], dialysis (n = 2) [34], molluscum contagiosum treated with imiquimod [19], and 3% minoxidil application [59]. In 15.4% of cases, other conditions were associated with the presentation of EVHC, most frequently steatocystoma (5.8%) [35,36,40,44,60–62], chronic kidney disease (1.7%) [34], ectodermal dysplasia (1.7%) [16,27], milia (1.7%) [19,44], and trichostasis spinulosa (1.7%) [11,24].