China
Africa
Explore chapters and articles related to this topic
Benign tumors
Published in Archana Singal, Shekhar Neema, Piyush Kumar, Nail Disorders, 2019
Histopathology reveals a lobulated mass extending into the subcutaneous tissue around the tendon in volar location and more into the lower dermis in dorsal location. In the former site there is usually a dense fibrous capsule that often also divides the tumor into lobules. The microscopic aspect of the lesion varies according to the number of mononuclear cells, giant cells, hemosiderin deposition, xanthomatous cells, and collagen. Xanthoma cell-rich areas are irregularly distributed and may even contain cholesterol clefts. The xanthoma cells also often contain fine hemosiderin granules. Reticulohistiocytoma has an almost identical histopathology.
Nonpigmented skin lesions
Published in Giuseppe Micali, Francesco Lacarrubba, Dermatoscopy in Clinical Practice, 2018
Pietro Rubegni, Linda Tognetti, Filomena Mandato, Michele Fimiani
Reticulohistiocytoma, also known as solitary epithelioid histiocytoma, is a localized benign form of histiocytosis that generally occurs in young adults or middle-aged people. It presents as an asymptomatic, reddish, dermal nodule that may spontaneously resolve over a period of months to years (Figure 25.3a).
Epithelioid sarcoma of the hand: a wolf in sheep's clothing
Published in Journal of Plastic Surgery and Hand Surgery, 2021
Jonathan Persitz, Eran Beit Ner, Igal Chechik, Timoret Keren, Erez Avisar
The patient was not adherent to the follow-up schedule. Two years after his second surgery he turned to his GP due to surgical site pain and was referred to a hand specialist who detected a recurrence of the mass at the same location. MRI exam of the hand identify an 8 × 5 mm subdermal oval mass, with high signal intensity after administration of IV Gadolinium (Figure 1). Due to the differential diagnoses of primary STS or metastasis, a chest CT was done without any pathology to mention. The patient underwent a third surgical intervention to remove the recurrent lesion. Surgical approach included wide surgical resection with healthy margins. Histopathologic findings suggested a reticulohistiocytoma. However, the high mitotic activity precluded this diagnosis. After repeated assessments of the specimens and multiple discussions, it was concluded that the samples showed similar features that are undoubtedly those of a malignant lesion. Due to the lack of specific immunophenotyped findings, the tumor was labeled as a high grade undifferentiated malignant epithelioid and spindle cell neoplasm. Despite lacking a clear evidence of a specific line of differentiation, the fact that the lesion has recurred repeatedly over five-year period, in the absence of any primary tumor elsewhere, favored this being a primary mesenchymal neoplasm, rather than some unusual metastasis from another site.