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Other Reactions from Gloves
Published in Robert N. Phalen, Howard I. Maibach, Protective Gloves for Occupational Use, 2023
T. Bullock, A. Sood, J.S. Taylor
Pressure urticaria, a form of physical urticaria, is either localized at the stimulus site (contact type) or associated with distant reactions, such as hypotension, tachycardia, tickle, or pruritus of the nose or fingertips (reflex type).9 Atopy is frequently absent, and lesions do not occur at night. Pressure urticaria arises after a single stimulus, and the skin reaction is not a typical wheal but rather a reddened, deeper, sometimes painful swelling of the angioedema type. Urticarial dermographism may be associated with pressure urticaria. Pressure urticaria and urticarial dermographism can be classified as immediate (3–30 minutes) or delayed (2–6 h) types.9,87
Urticaria and Angioedema
Published in Pudupakkam K Vedanthan, Harold S Nelson, Shripad N Agashe, PA Mahesh, Rohit Katial, Textbook of Allergy for the Clinician, 2021
Jenny M Stitt, Stephen C Dreskin
Pressure-induced urticaria can occur independently or as a comorbid condition with chronic spontaneous urticaria. When it occurs independently, it is characterized by symptoms which occur 4 to 6 hours after the application of pressure to localized areas. Due to the time elapsed between exposure and symptoms, the condition is also termed ‘delayed pressure urticaria’ (Hiragun et al. 2013). Common sources of pressure include tight areas of clothing such as waistbands or straps and standing or sitting for prolonged periods of time. Manifestations of delayed pressure urticaria range from the sensation of edema in normal appearing skin, considered ‘delayed pressure angioedema’, to frank urticaria associated with marked swelling.
Metals as a Cause of Contact Urticaria Syndrome
Published in Ana M. Giménez-Arnau, Howard I. Maibach, Contact Urticaria Syndrome, 2014
Majken G. Hougaard, Jacob P. Thyssen
An open test with aluminum powder in petrolatum was positive after 1 hour on both the back and the forearm. A pressure urticaria test was negative. The patient was diagnosed with contact urticaria to both nickel and aluminum and was treated with antihistamine with excellent results.
Emerging treatments for chronic urticaria
Published in Expert Opinion on Investigational Drugs, 2022
In CINDU, the chronic urticaria can be reproducibly provoked. Depending on the stimulus, different CINDU subtypes are defined [2]. Provocation factors are cold in cold urticaria, heat in heat urticaria, UV and visible light in solar urticaria, shear forces in symptomatic dermographism, vibrations in vibratory urticaria/angioedema, and pressure in delayed pressure urticaria and enhanced body temperature, and/or sweating by physical or psychological stress in cholinergic urticaria. Avoidance of the specific and definite triggers is often not possible. The underlying causes of CINDU are unknown [2]. The pathomechanism of mast cell activation is supposed to be similar like in CSU. However, so far, in CINDU, sensitization to autoallergens has not been demonstrated conclusively, although there is some evidence that serum factors could be involved in solar urticaria and heat urticaria and sweat antigens in cholinergic urticaria. Similar to CSU, duration of CINDU is often for several years accompanied by a significant impairment of daily activities and quality of life [14].
Ligelizumab for the treatment of chronic spontaneous urticaria
Published in Expert Opinion on Biological Therapy, 2020
Being a next-generation high-affinity anti-IgE monoclonal antibody, Ligelizumab has the potential to effectively and safely treat not only chronic spontaneous urticaria but also other chronic urticaria types as has been previously demonstrated for Omalizumab in investigator-initiated trials, case series, and reports, e.g. symptomatic dermographism [47], cholinergic urticaria [48,49], cold urticaria [50], heat urticaria [51], solar urticaria [52,53], or delayed pressure urticaria [9]. Thus, Ligelizumab has the potential to become the preferred treatment not only for chronic spontaneous urticaria but also for difficult cases of similar conditions such as chronic inducible urticaria. Randomized controlled trials of Ligelizumab for chronic inducible urticaria subtypes such as cold urticaria, delayed pressure urticaria, and cholinergic urticaria are highly encouraged. At the moment there are virtually no approved treatments for these severe and limiting diseases, in which off-label Omalizumab use has shown efficacy but apparently less compared to Omalizumab in chronic spontaneous urticaria [9].
The effects of amniotic membrane stem cell-conditioned medium on photoaging
Published in Journal of Dermatological Treatment, 2019
Cita Rosita Sigit Prakoeswa, Febrina Dewi Pratiwi, Nanny Herwanto, Irmadita Citrashanty, Diah Mira Indramaya, Dwi Murtiastutik, Hari Sukanto, Fedik A. Rantam
In this study, the side effects after treatment were minor and included erythema for 2 days and urticaria for 3 days; both side effects resolved after two days of treatment with topical 1% hydrocortisone cream and antihistamine. The erythema that developed was likely due to the microneedling used for transdermal drug delivery (14,15). In the intervention group, only one subject developed urticaria, and this was probably because of an underlying history of pressure urticaria. According to Kaplan (2008) (16), pressure urticaria appears as a painful, erythematous, deep and local swelling that arises 3–6 h after the application of sustained pressure on the skin. According to Bariya (2012) (17), the use of microneedling could cause side effects, such as irritation, erythema, swelling, and others.