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Published in Richard F. Lockey, Dennis K. Ledford, Allergens and Allergen Immunotherapy, 2020
Emma Westermann-Clark, Stephen F. Kemp, Richard D. deShazo
Cholinergic urticaria, also called “heat urticaria,” is caused by increased core body temperature due to fever, stress, environmental factors, or exercise. Skin lesions frequently appear as 2–4 mm pruritic wheals (“microhives”) surrounded by erythema, which usually begin on the chest and spread over the body. Systemic manifestations, similar to those described for EIA, may also occur but are unusual. Subjects with this syndrome might develop wheals at the site where methacholine is injected or generalized urticaria when the body is warmed, as with a plastic occlusive suit [98].
Recognition, Treatment, and Prevention of Anaphylaxis
Published in Richard F. Lockey, Dennis K. Ledford, Allergens and Allergen Immunotherapy, 2014
Stephen F. Kemp, Richard D. deShazo
Cholinergic urticaria, also called “heat urticaria,” is caused by increased core body temperature due to fever, stress, environmental factors, or exercise. Skin lesions frequently appear as 2–4 mm pruritic wheals (“microhives”) surrounded by marked erythema. Systemic manifestations, similar to those described for EIA, may also occur but are unusual. Subjects with this syndrome might develop wheals at the site where methacholine is injected or generalized urticaria when the body is warmed, as with a plastic occlusive suit [70].
Perioperative Anaphylaxis from a Perspective of Temperature
Published in Journal of Investigative Surgery, 2022
Jie Luo, Qibin Chen, Su Min, Jian Yu
Temperature-related anaphylaxis most commonly occurs in patients with thermal stimuli (either cold or heat)-induced physical urticaria and cholinergic urticaria, which are more frequent, chronic, and debilitating than generally considered. Although these conditions are relatively rare during the perioperative period, there are more difficulties in diagnosis and treatment, especially for urgent surgical patients and no access to adequate medical history collection. For patients with these diseases or a related history who will undergo elective surgeries, sufficient preparations are required to prevent temperature-related stimuli and for treatment considering their hypersensitive diathesis. Since hypothermia is usually required in cardiac surgeries, special attention should be paid to patients undergoing these surgeries. External temperature-induced urticaria include cold urticaria (CU), heat urticaria (HU), and cholinergic urticaria (CholU), which are triggered by changes in body temperature.