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Hair transplantation
Published in John Dudley Langdon, Mohan Francis Patel, Robert Andrew Ord, Peter Brennan, Operative Oral and Maxillofacial Surgery, 2017
N Ravindranathan, E Antonio Mangubat
In the last two decades, the trend has been to transplant very small grafts using one to four hair follicles per graft unit. Now termed ‘follicular unit transplantation’ (FUT), modern technological advances have increased the number of follicle units transplanted in each session from an average of 1000 up to 3500.
Hair restoration surgery
Published in Jerry Shapiro, Nina Otberg, Hair Loss and Restoration, 2015
Dr. Robert Limmer started to use stereoscopic microscopes to dissect grafts and to reduce the damage done to the hair follicles in the dissection process [24]. They also identified desiccation as an important cause for graft damage and failure of transplanted hair follicles to grow. Limmer recognized that normal scalp hair naturally grows in groupings of one to four (“follicular units”). Limmer developed the methodology of follicular unit transplantation (FUT), where the donor strip of hair follicles was microdissected by a team of technicians into follicular units under magnification [24]. This was another step to improve the outcome of the mini-graft procedures and the cornerstone to modern follicular unit hair transplantation. FUT soon became the state-of-the-art hair transplant procedure [25–29].
Hair Transplantation for Women
Published in M. Sandra Wood, Internet Guide to Cosmetic Surgery for Women, 2013
Despite this being listed as an organization (.org), it is a private site. The goal of the site is to help you “make the best possible choices in dealing with your hair loss.” In addition to basic information on hair loss and hair transplantation, the site offers advice about realistic expectations, finding quality care, and tries to dispel some myths about hair transplantation. Follicular unit transplantation is emphasized as the preferred transplant method. A strength of the site is an extensive list of links. The International Alliance of Hair Restoration Surgeons is used as the physician locator service.
Artificial hair implantation for hair restoration
Published in Journal of Dermatological Treatment, 2022
Aditya K. Gupta, Maanasa Venkataraman, Emma M. Quinlan
Hair loss is a common problem that affects both men and women (1,2). Androgenetic alopecia (AGA) is the most common form of hair loss and can have a significant psychological impact (3,4). The two drugs approved for the treatment of AGA by the United States Food and Drug Administration (US FDA) and the European Medicines Agency include topical minoxidil (2% and 5%) for women and men, and oral finasteride for men (3,5,6). Low-level laser therapy is the only FDA-approved non-medical treatment for AGA; however, its efficacy has yet to be validated in higher quality studies (2,3,7,8). Surgical options for hair restoration include hair transplantation techniques such as follicular unit excision (FUE) and strip harvesting or follicular unit transplantation (FUT) (3,9). Minimally invasive, novel therapies such as microneedling, platelet-rich plasma (PRP), and exosome injections are also being investigated in the stimulation of hair growth (10,11).
A review of the treatment of male pattern hair loss
Published in Expert Opinion on Pharmacotherapy, 2020
Katherine York, Nekma Meah, Bevin Bhoyrul, Rodney Sinclair
Emergence and progression of androgenetic alopecia requires androgens. Progression of hair loss is inhibited and baldness partially reversed by finasteride, a type 2, 5AR inhibitor that prevents conversion of testosterone to its 5 times more potent metabolite DHT. The effect of finasteride on treating hair loss is proportional to the percentage reduction in follicular DHT. Follicular response to testosterone is site specific. Vertex follicles miniaturize. Beard, trunk and limb follicles enlarge, while eyebrow and eyelash follicles are relatively insensitive to androgens. Site specificity of follicles is preserved after follicular unit transplantation and this is known as the principal of donor dominance that underpins the therapeutic use of hair transplantation surgery to treat baldness.[91]
Safety concerns when using novel medications to treat alopecia
Published in Expert Opinion on Drug Safety, 2018
Hind M. Almohanna, Marina Perper, Antonella Tosti
Hair transplantation involves harvesting hair from a donor area, generally the occipital and posteroparietal scalp, using a single strip excision or small punch excisions to harvest individual follicular units and graft them onto a recipient location. This procedure may be limited by the availability of donor hair, such as when the density of the scalp donor area is inadequate or when the donor site contains a disease process, as well as the characteristics of the recipient site [26–28]. Additionally, the efficacy of hair transplantation depends on donor dominance; non-androgen-sensitive hair follicles keep their properties even when transplanted into alopecia-affected scalp locations. Follicular unit transplantation (FUT) is considered the standard of hair transplantation. This technique involves transplanting physiological follicular units which are smaller with less interfollicular tissue into finer, less traumatic recipient sites. The harvesting of follicular unit grafts from the donor area is typically achieved through excision of a hair-bearing strip [28].