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Combination Approaches: Using Fillers With Toxins and Energy-Based Devices
Published in Neil S. Sadick, Illustrated Manual of Injectable Fillers, 2020
IPL devices emit light between 500 and 1200 nm using a noncoherent and broad-spectrum wavelength filtered light source (11). Despite its broad spectrum, IPL can be modified to a specific wavelength range through the use of cut-off filters, thereby improving target selectivity. IPL is effective in treating features of photoaging by targeting both vascular lesions and pigmented lesions through photothermolysis of oxy/deoxyhemoglobin and melanin, respectively (12,13). In addition to improving cutaneous signs of solar elastosis, IPL has also been shown to stimulate dermal collagen production through the upregulation of procollagen 1 and 3 and downregulation of proteolytic enzymes like matrix metalloproteinases 1 and 2 (13–17). Adverse effects are generally mild and temporary following IPL treatment. Minor crusting and erythema should be anticipated, while purpura and striping of untreated areas are rarely seen (11,18). Furthermore, if appropriate precautions (e.g., longer interpulse delays, higher cut-off filters) are not taken in patients with darker skin types, residual dyschromia can occur (19).
Micropigmentation Applied to Oncology Patients
Published in Paloma Tejero, Hernán Pinto, Aesthetic Treatments for the Oncology Patient, 2020
Reparative and reconstructive micropigmentation allows the application of micropigmentation in lesions that are already stabilized or in areas that have dyschromia. With micropigmentation we can achieve the following: Camouflage scars that are already stabilized and that are not at risk of producing keloids or becoming hypertrophic scars.Camouflage donor or recipient areas of skin grafts and other dyschromias, artificially coloring the affected areas using mosaic or watercolor techniques.
Immunology of Skin and Reactivity
Published in Heather A.E. Benson, Michael S. Roberts, Vânia Rodrigues Leite-Silva, Kenneth A. Walters, Cosmetic Formulation, 2019
Krishna Telaprolu, Heather A.E. Benson, Jeffrey E. Grice, Michael S. Roberts, Philip L. Tong
Dyschromia, characterized by skin discolouration or patches of uneven colour, can be a challenging presentation, particularly among persons of colour. In Australia, dyschromia is often the result of chronic sun exposure resulting in Poikiloderma of Civatte (a scarf-like patch of dyschromia), atrophy and telangiectasia. Uneven skin tone has traditionally been managed with hydroquinone or corticosteroids, and although highly efficient, the treatment raises a number of safety concerns for local and systemic effects with long-term use.
Combination of pulsed dye laser and verapamil in comparison with verapamil alone in the treatment of keloid
Published in Journal of Dermatological Treatment, 2020
Fathia M. Khattab, Mohamad Nasr, Shrook A. Khashaba, Hagar Bessar
The combined effect of these two will result in a reduction in thickness, vascularity, and improvement in the appearance of the keloid. In our study, the lesions showed improvement over the sessions with a statistically significant improvement in length and flattening in height in group B as against group A while no such significance was seen in the breadth of these lesions. Among the modified MQS parameters assessed, it was found that overall appearance parameter showed an improvement of more than 50% in 43.3% of the lesions. The degree of hypertrophy showed more than 50% improvement in 40% of the lesions treated. Dyschromia showed more than 50% improvement in 33.4% while the texture was the least improved parameter with only 30% of lesions showing an improvement of more than 50%. Combination therapy of PDL with intralesional verapamil was significantly superior in efficacy compared to intralesional verapamil used alone.
Application of a new fractional radiofrequency device in the treatment of photoaging skin in Chinese patients
Published in Journal of Cosmetic and Laser Therapy, 2018
Yimeng Sun, Yao-Jia Luo, Zhengxiu Li, Ai jiao Yu, Lin Gong, Yuan hong Li
Chronic exposure to UV light causes aging of the skin, characterized by dyschromia, telangiectasia, laxity, wrinkles and rough skin texture. In Asians, of all the characteristics of photoaged skin, the most significant features are wrinkles and pigmentary changes (10,11). Prolonged exposure to UV light can lead to changes in dermal tissue, resulting in wrinkles and loss of elasticity. The dermis layer maintains skin elasticity through the extracellular matrix, including collagen, elastin and hyaluronic acid mucopolysaccharide (12). UV damage will cause dermal papilla fibrosis, collagen and elastic fiber degradation in the papillary dermis of photoaged skin.
Topical treatment for postinflammatory hyperpigmentation: a systematic review
Published in Journal of Dermatological Treatment, 2022
Marcus G. Tan, Whan B. Kim, Christine E. Jo, Karina Nabieva, Carly Kirshen, Arisa E. Ortiz
All primary studies written in English evaluating topical treatments for PIH were included. Studies that did not contain original data, evaluated energy-based devices as treatment, involved primary hyperpigmentation disorders (e.g. melasma), or non-human studies were excluded. PRISMA 2020 guidelines were followed. A search inquiry was performed on PubMed, MEDLINE, and EMBASE databases from conception to March 29 2021, with the search terms ‘topical’, ‘postinflammatory’, ‘hyperpigmentation’, ‘hypermelanosis’, ‘hyperchromia’ and ‘dyschromia’.