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The Child with Fever or a Rash
Published in Miriam Orcutt, Clare Shortall, Sarah Walpole, Aula Abbara, Sylvia Garry, Rita Issa, Alimuddin Zumla, Ibrahim Abubakar, Handbook of Refugee Health, 2021
Neal Russell, Bhanu Williams, Anna Battersby
Carefully examine the trunk and limbs for erythematous pruritic maculopapular rash, with evidence of ‘burrowing’ by the female scabies mite. Check the scalp, which is characteristically spared. Burrows appear as 0.5–1.5-cm grey irregular tracks. Sterile pustules (acropustulosis) may develop (particularly in infants) on the palms and soles of the feet. Vesicles are also possible in these areas. Always assess for signs and symptoms of secondary bacterial infection, cellulitis or sepsis.
Nail psoriasis
Published in Archana Singal, Shekhar Neema, Piyush Kumar, Nail Disorders, 2019
Characterized by subungual and periungual pustules and destructive pustulation of the nail unit (Figure 13.16), acropustulosis may occur as a part of pustular psoriasis, palmoplantar pustulosis, and acrodermatitis continua of Hallopeau.
Accident and Emergency
Published in Nagi Giumma Barakat, Get Through, 2006
Acropustulosis of infancy has an unknown aetiology, with pustules on the scalp, feet and hands. It appears at birth or during the first few weeks of life. They are sterile with a well baby and heal within 5-6 days. Answers: A, B, D, E
A review of disease burden and clinical management for generalized pustular psoriasis in China
Published in Expert Review of Clinical Immunology, 2022
Based on literature and our clinical experience to date, the differential diagnoses of GPP include acute generalized exanthematous pustulosis, superficial candidiasis, subcorneal pustular dermatosis, Stevens-Johnson syndrome – a severe mucocutaneous disease characterized by severe purulent conjunctivitis, severe stomatitis with extensive mucosal necrosis, and purpuric macule, and is caused by drug exposure or infections; with a pustular eruption as an unusual form of the disease [29,30], amicrobial pustulosis of the folds, pemphigus foliaceous, IgA pemphigus subcorneal pustular dermatosis type, transient neonatal pustular melanosis, acropustulosis of infancy and SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis), adding to the challenge of correctly diagnosing GPP [1,31–34]. Moreover, diagnostic criteria for GPP vary between research entities. ERASPEN criteria stipulate that a diagnosis of GPP can be confirmed only upon disease relapse >1 episode or persistence >3 months [26]. However, the Japanese Dermatological Association (JDA) guidelines state that a definitive diagnosis of GPP can be made if patients show the following four features: 1) systemic symptoms, including fever and fatigue; 2) systemic or extensive flush accompanied by multiple sterile pustules that can sometimes merge as lakes of pus; 3) neutrophilic subcorneal pustules histopathologically characterized by Kogoj’s spongiform pustules; and 4) the above clinical and histological features occur repeatedly [35]. GPP should be suspected in patients with the second and third features [35].
The clinical, humanistic, and economic burden of generalized pustular psoriasis: a structured review
Published in Expert Review of Clinical Immunology, 2020
Saifuddin Kharawala, Amanda K. Golembesky, Rhonda L. Bohn, Dirk Esser
During the post-flare chronic phase, patients experienced a variety of skin lesions including acropustulosis, annular plaque psoriasis, inverse psoriasis, plaque, erythroderma, and PP [17,19]. Of these, plaque psoriasis lesions were the most common manifestation (50%), followed by pustular lesions (22%).