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Colds/Coryza
Published in Charles Theisler, Adjuvant Medical Care, 2023
Zinc acetate or gluconate lozenges (13.3 mg zinc) taken every 2–3 waking hours significantly reduced the duration of the common cold by about 50%. Zinc gluconate is effective, whereas zinc picolinate, zinc citrate, and zinc aspartate are not. It is important to begin treatment at the first sign of a scratchy throat.1,2,3,4,5
Trace Minerals
Published in Luke R. Bucci, Nutrition Applied to Injury Rehabilitation and Sports Medicine, 2020
Of particular interest are the effects of zinc chelates such as zinc monomethionine, zinc histidinate, zinc citrate, zinc aspartate, and zinc picolinate. These compounds appear to be zinc ligands in vivo808,809 and also improve bioavailability over zinc sulfate.822 It is believed that organic zinc salts would have less potential toxicity and less interference from and with other minerals. For example, zinc monomethionine uptake is independent of fiber intake, unlike zinc sulfate, which exhibits depressed uptake with fiber intake. An animal study compared zinc sulfate to zinc cysteamine-N-acetate during bone healing and found better results and less toxicity from the organic chelate.823 Thus, preliminary evidence indicates that organic zinc salts behave quite differently from zinc sulfate. Therapeutic trials with organic zinc chelates may offer a significant difference in results from zinc sulfate trials and are therefore worthy of further attention.
Basic Facts about Micronutrients
Published in Kedar N. Prasad, Micronutrients in Health and Disease, 2019
Minerals (selenium and zinc): Commonly used selenium is in the form of L-selenomethionine (an organic form) and sodium selenite (an inorganic form). Selenium rich foods include Brazil nuts, lima beans, brown rice, and seeds (sunflower, sesame, and flax). Zinc compounds such as zinc picolinate, zinc gluconate, zinc acetate, and zinc oxide are utilized in the supplement. Rich food sources include oyster, crab, lobster, meat, poultry, legumes, nuts, seeds, and whole grain.
Non-pharmacologic approaches for hidradenitis suppurativa – a systematic review
Published in Journal of Dermatological Treatment, 2021
Aleksi J. Hendricks, Penelope A. Hirt, Sahil Sekhon, Alexandra R. Vaughn, Hadar A. Lev-Tov, Jennifer L. Hsiao, Vivian Y. Shi
Zinc supplementation alone or in addition to topical triclosan is a promising adjunctive HS treatment. However, both aforementioned zinc supplementation studies reported gastrointestinal distress symptoms in ∼20% of patients, including nausea, abdominal pain, and esophagitis with zinc gluconate supplementation (72,73). Zinc picolinate is an alternative zinc complex with improved absorption that releases less free elemental zinc, thereby minimizing gastrointestinal distress (74). Patients should be cautioned that excess zinc supplementation might lead to copper deficiency. Higher doses of zinc should be taken with trace copper to avoid copper deficiency, at a minimum of the recommended dietary allowance of 900 µg daily (75). In patients taking high-dose zinc long-term, providers should be vigilant for signs and symptoms of copper deficiency including anemia, neutropenia and in severe cases, neurological manifestations such as neuropathy or ataxia (76,77).
Protective Effect of Leaf Ethanolic Extract Etlingera hemisphaerica Blume Against Mercuric Chloride Toxicity in Blood of Mice
Published in Journal of Dietary Supplements, 2019
Aceng Ruyani, Rendi Zulni Eka Putri, Pauzi Jundara, Efri Gresinta, Irwandi Ansori, Agus Sundaryono
Imunos was used in this research as a positive control for LE3H treatment. The ingredients of Imunos are Echinacea purpurea, zinc picolinate, selenium, and ascorbic acid. Echinacea purpurea extract plays an important role in the protection against toxicity (Rezaie et al., 2013). Zinc picolinate is zinc complex with picolinic acid, which can be used to increase zinc absorption in humans (Barrie et al., 1987) for supporting optimal metabolism. Selenium is an essential micronutrient in mammals, but is also recognized as toxic in excess. It exerts its biological functions through selenoproteins. Most selenoproteins, whose functions are known, are involved in redox systems and signaling pathways (Kurokawa and Berry, 2013). The results of verification through phytochemical test showed that tannins, flavonoids, and terpenoids could be detected in Imunos (Table 2). From these facts, it can be stated that LE3H and Imunos have the same two compounds: flavonoids and tannins. Therefore, the protective effect of LE3H is derived from the antioxidant activity of flavonoids (Pietta, 2000) and iron chelation activity of tannins (Ghate et al., 2015). Previous experiments demonstrated the interaction between selenium and methylmercury and, according to the facts, selenium can be applied as chelation therapy for acute mercury poisoning (Watanabe, 2002).