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Overweight/Obesity
Published in Charles Theisler, Adjuvant Medical Care, 2023
Psyllium (psyllium seed, Metamucil) is the seed of the plantain plant that is rich in a spongy fiber called mucilage. When psyllium comes in contact with water, its mucilage absorbs the fluid and expands substantially. In the stomach, psyllium expansion can produce feelings of fullness.21
Using Medication Wisely
Published in Melissa G. Hunt, Aaron T. Beck, Reclaim Your Life From IBS, 2022
Melissa G. Hunt, Aaron T. Beck
Bulk-Forming Fiber Supplements help keep water in the stool (making it softer) and add volume to the stool. That is, by trapping water in the stool they stop the colon from extracting it. Psyllium (the main ingredient in Metamucil) is soluble fiber. It dissolves in water and turns into a slippery gel that absorbs water and makes the stool bulkier but also softer and more slippery. Because it is fermented by bacteria, it can also make you feel more gassy and bloated. Methylcellulose (the main ingredient in Citrucel) is a different type of soluble fiber. It also adds bulk and volume to the stool and maybe slightly less likely to cause gas. You need to take both of these products with plenty of water.
Inflammatory bowel disease
Published in Mark Davenport, James D. Geiger, Nigel J. Hall, Steven S. Rothenberg, Operative Pediatric Surgery, 2020
Aimee G. Kim, Samir K. Gadepalli, James D. Geiger
Clinical outcomes important to the pediatric patient with UC after RP include bowel movements per day (including night-time stools), urgency, and continence. Patients may have 7–15 loose bowel movements per day initially after reversal of the diverting ileostomy or after RP without ileostomy, and patients and families should be prepared and advised as such. Still, patients should be monitored for signs and symptoms of dehydration and/or evidence of skin breakdown by the perineum. Loperamide, Metamucil, and occasionally cholestyramine may be prescribed to control the volume, frequency, and consistency of the stool. Over the course of several months, patients will settle on an average of 4–8 stools per day, with 0–1 per night. Younger patients tend to have more night-time bowel movements. Incontinence and seepage are rare, especially in long-term follow-up, and may be indicative of pouchitis; these symptoms and expectations are important to discuss with patients prior to surgery.
Effects of a Laxation and Probiotic Bowel Preparation Regimen: A Randomized Controlled Trial in Patients Undergoing Prostate Radiation Therapy
Published in Nutrition and Cancer, 2020
Nicole Weston, Georgina Luscombe, Kerith Duncanson
The two laxatives used for this study vary in their modes of action in facilitating rectal evacuation. The osmotic laxative Movicol®, acts by attracting water osmotically into the large intestine with the resulting bulk stimulating peristalsis. Although osmotic laxatives have the potential to cause flatulence and diarrhea (13) when used in a lower dose in the form of Movicol half strength® such as in this study, the occurrence of gas was statistically lower compared to the bulking laxative. The bulk-forming laxative Metamucil®, by comparison, acts by retaining water so the stool remains soft and large stimulating peristalsis. Psyllium, the main component in Metamucil® is only partially fermented and retains its water-holding gelled structure throughout the large bowel (14). This can minimize fermentation by gut microbiota and reduces bowel gas (14). Results from this study however, have demonstrated that participants in the bulking laxative group experienced statistically higher gas rating levels compared to the osmotic laxative group. This suggests that the level of fermentation of the psyllium by an individual’s gut microbiota is high enough to impact on gas levels in the rectum. Despite the concurrent addition of beneficial probiotics, it is predicted that the difference between groups would have been higher without probiotic supplementation, or gas levels more pronounced in the bulking laxative group, given their known desirable effect on microbiota.
Morphological and functional impairment in the gut in a partial body irradiation minipig model of GI-ARS
Published in International Journal of Radiation Biology, 2020
Amandeep Kaur, Gabriëlla A.M. ten Have, Bernadette Hritzo, Nicolaas E.P. Deutz, Cara Olsen, Maria Moroni
Oral supportive care was provided in the form of antibiotics (2 mg/kg Gentamicin SID and 10 mg/kg Amoxicillin BID), antipyretic/anti-inflammatory/analgesic (2.2 mg/kg Carprofen BID), and gastrointestinal protectant (1g sucralfate BID) between day 3–30 post-IR. Ondansetron (Zofran®) at 0.07–1 mg/kg SC and loperamide (Imodium®) at 0.04 mg/kg PO BID were also administered to affected animals on as needed basis for vomiting and diarrhea, respectively. Dietary supplementation and oral hydration was offered in the form of moistened/liquid food, Metamucil®, pumpkin mash, Pedialyte®, and applesauce.