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Head and Neck Pathology
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Ram Moorthy, Adrian T. Warfield, Max Robinson
Warthin’s tumour is composed of ciliated, bi-layered oncocytic epithelium supported by reactive lymphoid stroma (Figure 26.7b). The cystic areas contain amorphous debris. Warthin’s tumour can undergo infarction or degeneration and metaplastic change either spontaneously or secondary to manipulation (e.g. FNAB, core biopsy). Benign oncocytic epithelial inclusions are commonly seen in intra-parotid and para-parotid lymph nodes. These inclusions probably account for Warthin’s tumour’s propensity for multicentricity and bilaterality. Malignant transformation, either carcinomatous or lymphomatous, is rare.
Case 12
Published in Simon Lloyd, Manohar Bance, Jayesh Doshi, ENT Medicine and Surgery, 2018
Simon Lloyd, Manohar Bance, Jayesh Doshi
Most likely this is a benign parotid tumour. As 80% of benign parotid tumours are pleomorphic salivary adenomas (PSAs), this would be the most likely diagnosis. Other possible diagnoses include other benign parotid tumours such as Warthin's (adenolymphoma) tumour, intra-/extra-parotid lymph node, malignant mass, metastasis or haemangioma.
Salivary Glands
Published in John C Watkinson, Raymond W Clarke, Christopher P Aldren, Doris-Eva Bamiou, Raymond W Clarke, Richard M Irving, Haytham Kubba, Shakeel R Saeed, Paediatrics, The Ear, Skull Base, 2018
Neil Bateman, Rachael Lawrence
Sarcoidosis is rare in children. When the parotid gland is involved, this can take the form of gland swelling, often as part of Heerfordt syndrome (or uveoparotid fever). Facial palsy can also occur. Non-caseating granulomas may be identified in minor salivary glands on sublabial biopsy and this was used as a diagnostic test, but it is now rarely needed. Cervical tuberculosis (caseating granuloma) can present in the parotid lymph nodes. Treatment is medical (see Chapter 37, Cervicofacial infections).
Assessment of lingual sentinel lymph nodes metastases using dual-modal indirect CT/MR lymphography with gold–gadolinium-based nanoprobes in a tongue VX2 carcinoma model
Published in Acta Oto-Laryngologica, 2018
Yue Yang, Benqing Zhou, Jian Zhou, Xiangyang Shi, Yan Sha, Haitao Wu
Rabbit tumour-bearing models are commonly used for cervical lymph nodes studying in head and neck carcinomas. Seki and Fujimura identified the metastases in the deep cervical lymph nodes on 10 days tumour-bearing rabbits after VX2 carcinoma transplantation [14]. Hamaguchi used magnetoliposomes to confirm deep cervical lymph node metastases following implantation of VX2 carcinoma cell suspension into the lingual margin of the tongue [15]. In the present study, the presence of metastases in deep cervical lymph nodes were confirmed histopathologically, and the position was consistent with that of black-stained nodes at autopsy and enhanced nodes on CT-LG and MR-LG, so the deep cervical lymph nodes were confirmed to be the lingual SLNs, which was consistent with our previous studies [10,11,16]. Furthermore, some non-SLNs (submandibular and parotid lymph nodes) were also black-stained at autopsy, but no enhancement was observed on CT-LG or MR-LG images. It is likely that the drainage of the Gd–Au PENPs in non-SLNs was not sufficient to impart better imaging capacity.
Primary cutaneous anaplastic large-cell lymphoma of the eyelid: report of two cases and review of the literature
Published in Orbit, 2021
Adriana Iuliano, Federica Fossataro, Maria Paola Laezza, Vittoria Lanni, Massimo Mascolo, Silvia Varricchio, Giovanni Uccello, Fausto Tranfa, Diego Strianese
For Patient 2, lymphatic involvement (left parotid lymph node) was detected by the PET-CT scan, while the bone marrow biopsy came back negative. The patient, therefore, underwent radiation therapy (20 Gy) in the affected regions. For the first twelve months, there was no evidence of local or systemic recurrence in this patient.