China
Africa
Explore chapters and articles related to this topic
Clinical Perspective on Dual Energy Computed Tomography
Published in Katsuyuki Taguchi, Ira Blevis, Krzysztof Iniewski, Spectral, Photon Counting Computed Tomography, 2020
Charis McNabney, Shamir Rai, Darra T. Murphy
Contrast induced nephropathy (CIN) is a serious adverse event that may result from the administration of iodinated contrast media in CTA. Treatment is not definitive but instead supportive in nature, with prevention being the cornerstone of management (Mohammed et al. 2013). The dose-effect relationship between administered contrast medium volume and incurring renal toxicity is well cited. By virtue of low energy monochromatic imaging in DECT, up to 50% less iodinated contrast volume is required compared to SECT to produce images without compromising image interpretability (Raju et al. 2014). Risk factors for CIN are including baseline renal function, diabetes, heart failure, male sex, hypertension, and anemia (Mohammed et al. 2013). Many of the risk factors for CIN overlap with and may be prevalent amongst patients with vascular disease, a significant indication for CTA. Therefore, reducing iodinated contrast volume will significantly reduce risk and subsequently incidence of CIN amongst an already at risk patient population (Mohammed et al. 2013).
Health Informatics for Research Applications of CAD
Published in de Azevedo-Marques Paulo Mazzoncini, Mencattini Arianna, Salmeri Marcello, Rangayyan Rangaraj M., Medical Image Analysis and Informatics: Computer-Aided Diagnosis and Therapy, 2018
Reporting: An adverse event (AE) is any untoward medical occurrence in a patient or clinical investigation subject, disregarding whether that event is related directly to the trial or not (e.g., car accident). Such AE is considered as serious (serious adverse event, SAE) if it results in death, hospitalization, persistent or significant disability, congenital anomaly, or birth defect. AE and SAE need special treatment for reporting to the authorities. After the trial, statistical analysis is performed and the final results are reported.
STUDY PROTOCOL – pulsed radiofrequency in addition to transforaminal epidural steroid injection in patients with acute and subacute sciatica due to lumbosacral disc herniation: rationale and design of a phase III, multicenter, randomized, controlled trial
Published in Expert Review of Medical Devices, 2020
Roberto Scipione, Giulia Alfieri, Alessandro De Maio, Emanuela Panella, Simone Napoli, Luca Bianchi, Nunziante Pandaloro, Alberto Bazzocchi, Giancarlo Facchini, Ugo Albisinni, Paolo Spinnato, Carlo Catalano, Alessandro Napoli
Adverse events. Data regarding treatment-related side-effects will be collected for each patient in both arms. A serious adverse event is defined as any adverse event or reaction, regardless of causality, that resulted in death, is life-threatening, requires hospitalization, or is considered to be an important medical event.Global Perceived Effect. This system evaluates current symptoms at week-52 compared to baseline, on a scale ranging from −5 (symptoms are vastly worse), to 0 (unchanged symptoms), to +5 (complete recovery) [29].Satisfaction with the current status. At 52 weeks, patients were asked to express a subjective judgment about their current clinical status in terms of percentage, with 0% indicating completely unsatisfied and 100% indicating completely satisfied.Adherence to the protocol. For each group, the number of patients exiting the study for other therapeutic options will be recorded.