China 
Africa 
Explore chapters and articles related to this topic
Metabolic Engineering
Published in Jean F. Challacombe, Metabolic Pathway Engineering, 2021
Bioprocess (or biochemical) engineering focuses on the design, construction, and application of processes involving biological organisms or organic molecules. The applications of bioprocess engineering include the mass production of biofuels, food, biopolymers, industrial enzymes, and pharmaceuticals, as well as the development of advanced biotechnology and water treatment processes [49–51]. To develop microbial systems that can effectively produce desired products involves the design and development of microbial cell factories and improved bioprocesses to facilitate the production of industrial compounds [49, 52, 53]. Optimizing a microbial cell might involve adding multiple traits to the genome and/or generating the right conditions to express a desired phenotype. Transcriptome profiling can be implemented in combination with fluxome analysis and this approach has been used to improve the production of microbial natural products for pharmaceutical use [54]. Transcriptome analysis can be used to identify transcriptional regulators, which can be manipulated to optimize the production of bulk chemicals such as succinate [55]. The application of transcriptome analysis in bioprocess engineering provides an increased understanding of cellular regulation on a global level, which can be exploited to understand (and then optimize) the responses of cells to their environment or to genetic perturbations [52].
Introduction
Published in Debabrata Das, Debayan Das, Biochemical Engineering, 2019
Biochemical engineering (also termed bioprocess engineering) is a branch of chemical engineering that mainly deals with the design and construction of unit processes that involve biological organisms or molecules, such as bioreactors, upstream processing, and downstream processing (Fig. 1.4). Biochemical process is an essential part of several food, chemical, and pharmaceutical industries. These processes make use of microbial, animal, and plant cells and components of cells such as enzymes to manufacture new products and also for waste treatment. Biochemical engineering may be considered a multidisciplinary field that implements engineering principles to design and operate unit processes required to successfully produce high-quality bioproducts. Chemical engineering principles play a central role in producing biochemical products on a large scale for marketing in purified form.
Application of Industry 5.0 in the Production of Fine Chemicals and Biopolymers
Published in Pau Loke Show, Kit Wayne Chew, Tau Chuan Ling, The Prospect of Industry 5.0 in Biomanufacturing, 2021
Nurul Natasha binti Azhar, Kai Ling Yu, Tau Chuan Ling, Pau Loke Show
Biochemical engineering is a field that has the discipline of chemical engineering at its core but adopts the concepts of biochemistry, bioorganic and bioinorganic chemistry as well as cell and molecular biology (Clark and Blanch 1997). In layman terms, biochemical engineering uses living organisms, or the chemical products that they produce such as enzymes, to develop new processes that produce chemical or biological materials (Clark and Blanch 1997). Early applications of biochemical engineering began when humans used yeast and fungi to make bread, wine, cheese and beer (Clark and Blanch 1997). Recent decades show that biochemical engineering has progressed to create biodegradable plastic containers from microbes (Philbrook, Alissandratos, and Easton 2013) as well as antibiotics (Najafpour 2015) and electrodes from fungi (Ludwig et al. 2013). One of the key environmental advantages of applying biochemical engineering concepts in a process is the fact that the processes are able to produce complex polymers and chemical compounds that cannot be achieved through conventional chemical production processes while having mild operating conditions and minimum waste generated (Takors 2020). In doing so, the environmental impacts related to the waste management of the process can be significantly reduced (Takors 2020). The Fifth Industrial Revolution presents the concepts of mass personalization and the collaboration between man and artificial intelligence, which can present an opportunity for the field of biochemical engineering to take part in the new manufacturing revolution. Biochemical engineering can partake in IR 5.0 through the advances and the applications of different fields such as white biotechnology, synthetic biology and evolutionary algorithms in the production process to create processes with higher flexibility at a lower environmental and economic cost. The concepts developed from the combination of the abovementioned fields with biochemical engineering can then be applied in the production processes of various manufactured goods including fine chemicals and biopolymers.
From the editor’s desk – special issue COVID-19
Published in Indian Chemical Engineer, 2020
It is a widely accepted fact that Chemical Engineering is a versatile discipline and characterised as ‘borderless chemical engineering science’. Chemical Engineers work in a vast area of Thermodynamics to predict outcome of a system, Chemical Reaction Engineering and Catalysis coupled with Transport Phenomena, Control and Instrumentation, Materials Design and Engineering, Biochemical Engineering and Biotechnology, Environmental and Pollution Mitigation, Data Science, Semiconductor Manufacturing and many more. This whole gamut of studies directly or indirectly contributes to the global research endeavour for Covid-19 treatment. We, thus, decided to bring out a COVID-19 Special Issue of Indian Chemical Engineer (ICE) so that knowledge about the work done in India in a short period of time can be disseminated and shared throughout the world for the benefit of COVID-19 warriors, policy makers and Government officials, who are closely involved in this battle. Council of Scientific & Industrial Research (CSIR) through its 38 Institutes all over India has been working at war-footing to find a way out of this catastrophe. This effort has been much appreciated by the Government of India, the general public and the media.
Production of highly active fungal milk-clotting enzyme by solid-state fermentation
Published in Preparative Biochemistry & Biotechnology, 2019
Cirium V. Chinmayee, Cheral Vidya, Amsaraj Rani, Sridevi Annapurna Singh
Microorganisms, particularly fungi, have attracted attention lately, as potential source of a wide array of proteases, including milk clotting enzymes.[10] Fungi can grow on cost-effective substrates and secrete considerable quantities of enzymes, which could relatively ease downstream processing. Also, the ability of fungal proteases to remain active over a wide range of pH and temperature has rendered them particularly interesting.[10,11] A considerable amount of work has been done in recent years to understand the biochemical engineering aspects of solid-state fermentation (SSF) and the nature of microorganisms best suited for SSF.[11,12]
Faculty wide curriculum reform: the integrated engineering programme
Published in European Journal of Engineering Education, 2021
John E. Mitchell, Abel Nyamapfene, Kate Roach, Emanuela Tilley
In 2011, the UCL Faculty of Engineering Science undertook a major review and revision of all its undergraduate educational programmes. This led, in 2014, to the introduction of the Integrated Engineering Programme (IEP) across eight departments and eight different programmes (each programme having a three-year Bachelors (BEng/BSc) and a four-year Integrated Masters (MEng/MSci) variant). The programmes are Biochemical Engineering, Biomedical Engineering,2 Chemical Engineering, Civil Engineering, Computer Science, Electronic and Electrical Engineering, Management Science3 and Mechanical Engineering. The first graduates from the three-year programmes graduated in September 2017, whilst the first four-year cohort graduated in September 2018.