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Computational RSM modelling of dentate nucleus neuron 2D image surface
Published in Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 2018
Ivan Grbatinić, Nemanja Rajković, Nebojša Milošević
The dentate nucleus occupies a central position in the cerebellar circuitry, serving as a relay centre for fibres coming from the cerebellar cortex, namely from the axons of Purkinje cells (Chan-Palay 1977). It represents the largest and phylogenetically most recent of the cerebellar white matter nuclei and plays an important role as a major relay centre between the cortex and the other parts of the brain. It receives its afferents from the premotor cortex and supplementary motor cortex (via the pontocerebellar system) and its efferents project via the superior cerebellar peduncle through the red nucleus to the ventrolateral thalamus (crossing over at the pontomesencephalic junction). It is responsible for the planning, initiation and control of volitional movements (Mathiak et al. 2002).