Alternative and Complementary Medicine in Treating Fungal Dermatophytic Infections
Anne George, K. S. Joshy, Mathew Sebastian, Oluwatobi Samuel Oluwafemi, Sabu Thomas in Holistic Approaches to Infectious Diseases, 2017
Punica granatum L. (Punicaceae) is a small multi-stemmed shrub/tree 5–10 m tall. Canopy open, crown base low. Stem woody and spiny, bark smooth and dark grey. Leaves simple, 2–8 cm long, oblong or obovate, glabrous, oppositely placed, short-petioled surface shining. Flowers regular, solitary or in fascicles at apices, 4–6 cm. Petals lanceolate, 5–7, wrinkled and brilliant orange-red. Hypanthium colored, 58 lobed. Anthers numerous. Calyx persistent. Fruit a round berry, 5–12 cm, pericarp leathery. Interior compartmentalized with many pink-red sections of pulp-like tissue, each contains a seed grain. Fruits globose with persistent callipe and a coriaceous woody rind. Seeds numerous, angular with fleshy testa, 1.3 cm long (Arun and Singh, 2012). In 2008, Dutta et al. found that water extract of P.granatum was detrimental to dermatophytes and this was confirmed with result obtained by Shrivastav et al. (2013) against the growth on T.tonsurans, T.mentagrophytes, T.rubrum, T.equinum, M.gypseum, M.nanum, M.audouinii.
Anti-Hyperglycemic Property Of Medicinal Plants
Amit Baran Sharangi, K. V. Peter in Medicinal Plants, 2023
Punica granatum, commonly known as pomegranate, is a member of Lythraceae family. It is indigenous to Iran and Northern India and widely harvested in Middle East and Caucasus region, Southern, and Central Asia, Northern Africa and many others. Khalil et al. (2004) treated hyperglycemic rats with aqueous peel extract of pomegranate (430 mg/kg body weight) for 4 weeks and found that blood glucose level of diabetic rats considerably reduced and number of beta islet cells were increase due to which it ultimately helps in more insulin secretion. In another study, ethanolic extract of pomegranate leaves at a dose of 0.5 g/kg were given to diabetic rats for 7 days. It was reported that ethanolic extract considerably reduced the blood glucose levels, total cholesterol, triglycerides, LDL, and increased serum HDL (Das et al., 2012). Other studies have been conducted to isolate the phenolic constituents in the peel (Kulkarni et al., 2004; Gil et al., 2000), phytochemical constituents in the fruit rinds (Jain et al., 2012) to decipher the chemical constituent responsible for anti-hyperglycemic activity.
Biblical times
Michael J. O’Dowd in The History of Medications for Women, 2020
The pomegranate (Punica granatum) is an Oriental fruit much cultivated in warm countries. It takes its name from the Latin pomum, apple, and granatum, having many grains or seeds. ‘Punic’ refers to ancient Carthage (Latin punicus or poeni, the Carthaginians) and the ‘Punic apple’ was the pomegranate. The first reference to pomegranate in the Bible is found in Exodus 28: 33–34: A golden bell [a pomegranate flower] and a pomegranate, upon the hem of the robe round about’. The Lord here commanded Moses that the skirts of the priestly robes, or ephods, should be embroidered in blue, purple and scarlet in imitation of the flowers and fruit of the pomegranate. In The Song of Solomon there are a number of references to the pomegranate, one of which relates to the perceived aphrodisiac qualities of the plant: ‘How beautiful you are my love ... let us [see] ... whether the pomegranates are come into flower; there will I give you my love’ (7: 6–12).
Anthocyanins rich pomegranate cream as a topical formulation with anti-aging activity
Published in Journal of Dermatological Treatment, 2021
Ahmed A. H. Abdellatif, Sulaiman Hamad Alawadh, Abdellatif Bouazzaoui, Ahmad H. Alhowail, Hamdoon A. Mohammed
Punica granatum L. or pomegranate is a kind of small tree native to Asia and Africa and is cultivated in different countries around the world. Secondary active metabolites such as alkaloids, tannins, polyphenolic compounds in addition to vitamins and minerals were identified in pomegranate (11–13). The bark of the plant is used as an anthelmintic agent (14), while astringent, antidiabetic and hemostatic effects were reported for all plant parts (15,16). The pomegranate plant’s parts have various biological activities that can be obtained from its extracts, for example: antimicrobial, antiviral, antioxidant, cancer preventive, anti-inflammatory, cardio-protective, and antidiabetic effects (17,18). The Chinese medicinal culture used the pomegranate’s peels to treat ulcers, trauma, hemorrhage, infections and digestive disorders for instance; dysentery and diarrhea due to its potent astringent and anti-inflammatory properties. On the other hand, Guatemala, India and Tunisia used water decoction of the peels to cure mouth infections and ulcers (19,20). The plant produces large edible fruits maturated between September and May according to the plant growing climate (21). Nowadays, pomegranate fruit is considered one of the main sources of antioxidant agents that have both health and medicinal beneficial properties (7,18). The pomegranate peel extract contains many bioactive compounds such as: Punicalagin, Ellagic acid, Punicalin, Quercetin, Gallic acid, Luteolin, Naringenin and Kaempferol (22,23). Furthermore, it has a known anti-oxidant, inflammatory and anti-carcinogenic properties (22).
Cardiac extracellular matrix modulation in a rat-diabetic model: biochemical and anti-oxidant beneficial effect of pomegranate (Punica granatum) peel extract
Published in Biomarkers, 2022
Houcine Dab, Amel Chehidi, Mounira Tlili, Anwar Ben Saad, Abdelmajid Khabir, Lazhar Zourgui
Several epidemiological studies suggested that vegetables are considered as useful dietary supplements (Assiri et al.2017) or provide antioxidants, including ascorbic acid, carotenoids, flavonoids, hydrolysable tannins, which can be used in food industries (Mekawi et al.2019), and prevent morbidity and mortality of cardiovascular diseases and cancers (Johnsen et al.2003, Rissanen et al.2003, Temple and Gladwin 2003, Mis et al.2018). The pomegranate, Punica granatum L., is an ancient, mystical, and highly distinctive fruit that is used in medicine (Mohammad and Kashani 2012). It has been shown efficient against several disorders including inflammation, cardiovascular diseases, type 2 diabetes and cancers (Vučić et al.2019, Baradaran et al.2020). The antioxidant properties of pomegranate peel are associated with its phenolics predominantly ellagitannins and flavonoids (Ismail et al.2012).
Antimicrobial activity of denture adhesive associated with Equisetum giganteum- and Punica granatum-enriched fractions against Candida albicans biofilms on acrylic resin surfaces
Published in Biofouling, 2018
Nara Ligia Martins Almeida, Luiz Leonardo Saldanha, Rafaela Alves da Silva, Karen Henriette Pinke, Eliane Ferraz da Costa, Vinicius Carvalho Porto, Anne Lígia Dokkedal, Vanessa Soares Lara
The antimicrobial activity of Punica granatum L. has been widely investigated (Endo et al. 2012; Bakkiyaraj et al. 2013; Labsi et al. 2016). The crude extract of P. granatum appears to be able to inhibit microbial adhesion. Researchers have claimed that oral bacterial biofilms and C. albicans were sensitive to this extract. Considering the gaps in knowledge about the mechanism of action and the bioactive principles of these microorganisms, tannins, which are the main polyphenols of the P. granatum extract, are believed to act on cellular metabolism through the cell walls. These compounds bind to the cell wall, cross this structure and interfere with the production of proteins and enzymes responsible for microbial adhesion (Vasconcelos et al. 2006). Thus, these herbal medicines could play an important role in the treatment and/or prevention of DS (Casaroto and Lara 2010; Alavarce et al. 2015). Overall, these herbal medicines contain compounds with antimicrobial activity, and, in recent years, there has been growing interest in identifying them (Endo et al. 2010; Anibal et al. 2013).
Related Knowledge Centers
- Anthocyanin
- Cochineal
- Epidermis
- Ovary
- Ph
- Polyphenol
- Fruit
- Berry
- Grapefruit
- Pomegranate Ellagitannin