Chronic Respiratory Diseases – Psychosocial Factors and Management
Michael E. Hyland
This entry addresses two chronic respiratory diseases, asthma and chronic obstructive pulmonary diseases (COPD) with a combined global prevalence of 2% of the general population (Hosseini et al., 2019). COPD is a generic label of diseases that includes chronic bronchitis and emphysema. Asthma and COPD are inflammatory diseases of the lung. Although the inflammatory mechanisms differ, in both cases inflammation creates airways restriction that causes symptoms, breathlessness, wheeze and cough.
Nanoparticle-Based Therapy in Chronic Obstructive and Infectious Lung Diseases: Past, Present, and Future Perspectives
Ana Catarina Moreira, Gaber E. Batiha, Noura H. Abdellah, Natália Cruz-Martin
Inhalable nanoparticulate nanomedicines has appeared as a promisor strategy for oral and/or intravenous administration, once it improves the therapeutic efficacy by decreasing the effective therapeutic dose needed and consequently reducing the risk of systemic side effects associated with high serum doses. Among the multiple pulmonary disorders, chronic respiratory diseases, like asthma and chronic obstructive pulmonary disease have been the most leading causes of death worldwide, where the lack of cell specific targeting has limited the therapeutic options available.
Vaccination and modern management of chronic obstructive pulmonary disease – a narrative review
Published in Expert Review of Respiratory Medicine 2022 Jun 23
Chronic obstructive pulmonary disease (COPD) carries a tremendous societal and individual burden, posing significant challenges for public health systems worldwide due to its high morbidity and mortality. Due to aging and multimorbidity but also in the wake of important progress in deciphering the heterogeneous disease endotypes, an individualized approach to the prevention and management of COPD is necessary.
Low Peak Inspiratory Flow Rates are Common Among COPD Inpatients and are Associated with Increased Healthcare Resource Utilization: A Retrospective Cohort Study
Published in International Journal of Chronic Obstructive Pulmonary Disease » Volume 17
This study examined the rates of airflow that patients with COPD could achieve while inhaling, using a device that measured PIF at different resistance levels, during hospitalization for an exacerbation of COPD. This single-center study used electronic health record data from 743 patients hospitalized for COPD exacerbations between January 2017 and June 2020.