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Long-term outcomes in newborn surgery
Published in Prem Puri, Newborn Surgery, 2017
Christian Tomuschat, Keith T. Oldham, Casey M. Calkins
Established in 1987, the EuroQOL Group initially comprised a network of international, multilingual, and multidisciplinary researchers from seven centers in Finland, the Netherlands, Norway, Sweden, and the United Kingdom. Currently, the group has expanded to researchers from Canada, Denmark, Germany, Greece, Japan, New Zealand, Slovenia, Spain, the United States, and Zimbabwe. The EQ-5D is a generic measure of health status that provides a simple descriptive profile and a single index value that can be used in the clinical and economic evaluation of healthcare and in population health surveys. The EQ-5D system consists of five dimensions: mobility, self-care, usual activity, pain/discomfort, and anxiety/depression. Each dimension has three levels designated simply as no problem, some problem, or severe problem, and subjects are asked to check the level that is most descriptive of their current level of function or experience in each dimension. These five dimensions yield 243 possible distinct “health states” comprising the classification system. The classification scheme has been assigned standardized scores derived from population-based samples of respondents asked to assign values to subsets of the 243 states. A set of valuation weights has been derived from a U.S. sample.55
Outcomes Research
Published in John C Watkinson, Raymond W Clarke, Louise Jayne Clark, Adam J Donne, R James A England, Hisham M Mehanna, Gerald William McGarry, Sean Carrie, Basic Sciences Endocrine Surgery Rhinology, 2018
Iain R.C. Swan, William Whitmer
The EQ-5D is a self-completed questionnaire with five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression.52 It is easy to complete and is very acceptable to patients. Responses can be scored using a weighted scale from a large general population sample.53 It is very brief with only five questions and three levels of response for each.54 It was compared with the Euroquol and the SF-36 in a survey of 1980 adults and the Euroquol was found to be less sensitive.54 However, it was originally intended to complement other forms of health-related quality of life measures. It has been widely used and its test-retest reliability is good.55
Literature review and selection of clinical tools and scales
Published in Ramar Sabapathi Vinayagam, Integrated Evaluation of Disability, 2019
The EQ-5D includes a questionnaire relating to mobility; self-care; education, work, household activities, family interaction, recreation; pain or discomfort; and anxiety/depression. It applies a “Three-Point Scale” to grade the severity of the problem (68).
Psychometric properties of the EQ-5D-3L in South Australia: a multi-method non-preference-based validation study
Published in Current Medical Research and Opinion, 2022
Mehrsa Zakershahrak, Pedro Henrique Ribeiro Santiago, Sneha Sethi, Dandara Haag, Lisa Jamieson, David Brennan
The most commonly applied instrument to measure HRQoL is the EQ-5D-3L9. The EQ-5D-3L is a generic measure developed by the EuroQol group in the 1980s to describe and value health according to five dimensions (mobility, self-care, usual activities, pain/discomfort and anxiety/depression)10. Items are rated on three response categories (“none”/“no”, “moderate”/“some”, “extreme”)11. Over the years, the EQ-5D-3L has been extensively used worldwide in over 160 different languages and different populations9,12. Validation studies in multiple countries and conditions have demonstrated overall good psychometric properties13–17. However, the EQ-5D-3L also has limitations, most notably ceiling effects when it is used in general population surveys9, and it has reduced sensitivity with respect to outcomes of disease-based studies18. These limitations led to the recent development of an alternative version, namely the EQ-5D-5L, which increased the EQ-5D-3L number of response categories from three to five9. Overall, using the EQ-5D-3L as a non-disease specific tool has proven important in assessing health outcomes and quality of life measures, and providing health care policies with economic value at a population level10.
A quality-of-life mapping function developed from a grass pollen sublingual immunotherapy trial to a tree pollen sublingual immunotherapy trial
Published in Journal of Medical Economics, 2020
Katherine Dick, Andrew Briggs, Robert Ohsfeldt, Tobias Sydendal Grand, Sarah Buchs
Subjects were asked to complete a daily record of rhinoconjunctivitis symptoms and medication use in an electronic diary. The six recorded symptoms included runny nose, blocked nose, sneezing, itchy nose, itchy eyes, and watery eyes. Subjects scored their rhinoconjunctivitis and asthma symptoms on a scale from 0–3 (0 = none, 1 = mild, 2 = moderate, 3 = severe). Daily medication use was measured on a scale from 0–36 according to the type and dosage of medication used. Subjects were also asked to complete two quality-of-life instruments every week: the EQ5D and the RQLQ24. EQ5D is a common PBM recommended by the National Institute for Health and Care Excellence (NICE) for estimation of health-state utilities. EQ5D measures quality-of-life in five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression25. EQ5D scores are only accurate for the day on which they are completed, so only daily scores recorded on the same day as the EQ5D scores were included in the analysis. The RQLQ is a disease-specific questionnaire consisting of 28 questions in seven domains, including activity limitation, sleep problems, nose symptoms, eye symptoms, non-nose/eye symptoms, practical problems, and emotional function. Subjects rate their health in these dimensions on seven levels from no impairment to severe impairment23.
Change in quality of life in relation to returning to work after acquired brain injury: a population-based register study
Published in Brain Injury, 2018
Marie Matérne, Thomas Strandberg, Lars-Olov Lundqvist
The EuroQol five dimensions questionnaire (EQ-5D) (27) was used to measure QoL (28). EQ-5D is a patient-reported outcome measure. It is a standardised instrument measuring status in five dimensions (mobility, self-care, usual activities, pain/discomfort and anxiety/depression). Each dimension has three levels of severity (16,27). These five dimensions are converted into a preference-based index value which can vary between −0.594 and + 1.000 (29). The value 1 corresponds to complete health and 0 corresponds to being dead. Notably, an index value below 0 is fully possible, because the respondents compare themselves with a population-based profile and some patients may rate their QoL as worse than being dead. The EQ-5D questionnaire also includes a visual analogue scale, EQ VAS (27), which is a rating scale from 0 (worst imaginable health) to 100 (best imaginable health) (30). Respondents mark a point along a 100 mm line to indicate their estimated overall health at that moment. The EQ-5D questionnaire has been shown to be a valid measure of QoL after stroke (31) and the EQ-5D index has been validated against populations in several countries.