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Biological Effects of Ayurvedic Formulations
Published in D. Suresh Kumar, Ayurveda in the New Millennium, 2020
G.R. Arun Raj, Kavya Mohan, R. Anjana, Prasanna N. Rao, U. Shailaja, Deepthi Viswaroopan
Paṭōla Kaṭurōhiṇyādi kvātha is a combination of six herbal ingredients viz. Trichosanthes dioica, Picrorhiza kurroa, Pterocarpus santalinus, Marsdenia tenacissima, Tinospora cordifolia and Cissampelos pareira (Upadhyay 1975b). This classical ayurvedic formulation has been reported by many practitioners to be effective in the treatment of liver disorders (Pawar et al. 2015). It is indicated in jaundice, skin disease, vomiting, fever, diseases due to poisoning, viral infections and liver diseases (Rao et al. 2015). It is widely used in the treatment of skin disease involving itching, pigmentation and burning sensations. It is useful in decreasing bad cholesterol and brings forth a potent antitoxic effect. It is used for metabolic corrections, liver dysfunctions and lowered immunity. It is effective in the management of spider poisoning (Sunitha and Hussain 2018b) and ulcers caused by snake bites (Roshni 2017; Vijayan et al. 2018). It improves digestion and relieves anorexia. It is a potent antimicrobial medicine too.
Preclinical Antidepressant-Like Effects of Terpenes, Polyphenolics, and Other Non-Flavonoid Phytochemicals
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
Tetrandrine is a bisbenzylisoquinoline alkaloid found in the Chinese medicinal plant, Stephania tetrandra.217 Administration of tetrandrine decreased immobility in the forced swim and tail suspension tests in mice. The substance also restored sucrose preference in mice that had been subjected to chronic unpredictable stress. Tetrandrine further restored hippocampal levels of serotonin and norepinephrine in stressed mice and in mice that been treated with reserpine, and maintained hippocampal levels of BDNF in stressed mice.218 Other structurally similar bisbenzylisoquinolines have shown antidepressant-like effects. Those include liensinine and neferine from Nelumbo nucifera219 and warifteine,220 a bisbenzylisoquinoline from Cissampelos sympodialis.
A-Z of Standardisation, Pre-Clinical, Clinical and Toxicological Data
Published in Saroya Amritpal Singh, Regulatory and Pharmacological Basis of Ayurvedic Formulations, 2017
Hemidesmus indicus R. Br., Rubia cordifolia L., Cissampelos pareira L.; fruits of Terminalia chebula Retz., Emblica officinalis Gaertn., Terminalia bellirica Roxb., Vitis vinifera L., Grewia asiatica L., Salvadorapersica L. and granules of Saccharum officinarum L. is used as a antipyretic. Gas chromatography-mass spectrometry led to the identification of 2-(1-oxopropyl)-benzoic acid as principal constituent (Gupta, Shaw and Mukherjee 2010).
Ethnomedicinal plants used for treatment of snakebites in Tanzania – a systematic review
Published in Pharmaceutical Biology, 2022
Neema Gideon Mogha, Olivia John Kalokora, Halima Mvungi Amir, David Sylvester Kacholi
This review reports 109 plant species belonging to 49 families to manage snakebite problems (Table 1). Globally, the highest number of medicinal plants used against snakebites was reported from India (Upasani et al. 2017), while in sub-Saharan Africa, Ethiopia (Yirgu and Chippaux 2019) recorded the highest number of plants, followed by Uganda (Omara et al. 2020) and Kenya (Omara 2020). This is probably because the highest number of ethnobotanical studies and reviews have been conducted in these countries, making the data more accessible. The majority of the documented plants in this review belong to the family Fabaceae 21 (19.3%), followed by Euphorbiaceae nine (8.3%), Rubiaceae seven (6.4%), Asteraceae and Combretaceae, each with four (3.7% each). The remaining 43 families were represented by less than four species each. The most cited plant species were Annona senegalensis Pers. (Annonaceae), Dichrostachys cinerea (L.) (Fabaceae), Antidesma venosum E.Mey. ex Tul. (Phylanthaceae), Cissampelos pareira L. (Menispermaceae) and Dalbergia melanoxylon Guill. & Perr. (Fabaceae) suggesting considerable potential for possessing snake envenomation bioactive compounds that can be isolated and combined with commercial antiserum to prepare snakebite antidotes. Details on all medicinal plant species with their respective family, local names, growth form, part used and the region in which they were reported are summarized in Table 1.
Protective potential of Angelica sinensis polysaccharide extract against ethylene glycol-induced calcium oxalate urolithiasis
Published in Renal Failure, 2018
Shengbao Wang, Xiaoran Li, Junsheng Bao, Siyu Chen
Several pharmacological and clinical studies of traditional medicinal plants used to treat urolithiasis have publicized their therapeutic potential in various in vitro and in vivo models. Furthermore, plants provide an inexpensive source of medicine for the majority of the world's population. Such medicines present minimal or no side effects and are considered safe; in addition, studies have indicated that various herbal plants such as Flos carthami [5], Ipomoea eriocarpa [6], Costus spiralis [7], Cissampelos pareira [8] and Herniaria hirsute [9], have been successfully proven as prophylactic and curative medicines for urolithiasis. All these reports suggest that herbal medicines may be a useful strategy for preventing renal stones.
Brazilian medicinal plants with corroborated anti-inflammatory activities: a review
Published in Pharmaceutical Biology, 2018
Victor Pena Ribeiro, Caroline Arruda, Mohamed Abd El-Salam, Jairo Kenupp Bastos
Alkaloids with anti-inflammatory properties have also been described in the literature. Many alkaloids have been isolated from native plants from Brazil, which have been studied for the treatment of inflammation, such as: Bukittinggine (12) isolated from Sapium baccatum Roxb. (Euphorbiaceae), which is able to suppress the levels of PGE2 (Panthong et al. 1998); berberine (13) found in species of the genus Berberies, which significantly decreases paw oedema (Küpeli et al. 2002), spectaline (14) obtained from Cassia spectabilis DC. (Fabaceae) a plant found in the northeastern region of Brazil (Viegas et al. 2008), and milonine (15) obtained from the leaves of Cissampelos sympodialis Eichler (Menispermaceae) (Melo et al. 2003), among others.