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Herbal Therapies
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
H. Shahrul, M. L. Tan, A. H. Auni, S. R. Nur, S. M. N. Nurul
Artemisia dracunculus L (Tarragon) is from the Asteracaceae and it has been used to treat gastrointestinal problems in several parts of India. The leaves of Artemisia scoparia are used for gastric disorder, treating intestinal parasites and indigestion. Matricaria recutita L. (syn. Matricaria chamomilla L., Chamomilla recutita (L.) consumed for various gastrointestinal conditions. Senecio rufinervis and Tanacetum gracile are used for stomach ailment and anti-helmintic, respectively. Locally, the powder of Tanacetum longifolium root is used for stomach ailment (Joshi et al., 2016).
Use of Essential Oils in Agriculture
Published in K. Hüsnü Can Başer, Gerhard Buchbauer, Handbook of Essential Oils, 2020
Catherine Regnault-Roger, Susanne Hemetsberger, Gerhard Buchbauer
Artemisia scoparia Waldst. and Kit. (Asteraceae) was tested on Achyranthes aspera L., Cassia occidentalis L., Echinochloa crus-galli (L.) P. Beauv., Parthenium hysterophorus L. and Ageratum conyzoides L. The inhibitory effect on seedling growth was greatest in the latter two weeds. When the EO was used on the weeds, it caused wilting and necrosis of sprayed parts. Also, a decreasing chlorophyll amount and ion leakage can be observed. This effect was greatest in E. crus-galli and P. hysterophorus. A. scoparia EO's main constituents are p-cymene, β-myrcene, and (+)-limonene (Kaur et al., 2010).
Inhibiting Insulin Resistance and Accumulation of Triglycerides and Cholesterol in the Liver
Published in Christophe Wiart, Medicinal Plants in Asia for Metabolic Syndrome, 2017
Ethanol extract of Artemisia scoparia Maxim. given orally to C57BL/6J mice on high-fat diet as part of 0.5% of diet for 4 weeks had no effect on fasting plasma glucose nor plasma cholesterol, attenuated plasma triglycerides, lowered fasting plasma insulin from about 10 to 6 ng/mL, potentiated the hypoglycemic effect of insulin in intraperitoneal insulin tolerance test.390 This supplementation had no effect on plasma leptin but increased plasma adiponectin by about 2-folds.390 At the hepatic level this extract prevented triglyceride and cholesterol accumulation, increased the expression of insulin receptor substrate-1/2, the phosphorylation of insulin receptor substrate-1, Akt and lowered protein-tyrosine phosphatase-1B evidencing increased insulin hepatic sensitivity.390 In the liver, the extract activated adenosine monophosphate-activated protein kinase and downstream targets fatty acid synthetase, sterol regulatory element-binding protein-1c and of 3-hydroxy-3-methylglutaryl-coenzyme A CoA reductase.390 In the liver, activation of adenosine monophosphate-activated protein kinase promotes insulin receptor sensitivity by inhibiting mTORC1 alleviating thus insulin receptor inhibition by S6K1.391 Besides, S6K1 activates liver X receptor, which induces the expression of sterol regulatory element-binding protein-1c.392 The plant contains rutin which was given at 4 doses of 20 mg/kg at 12 hours interval to mice prevented paracetamol-induced hepatic insults as evidenced by decreased plasma levels of aspartate aminotransferase.393 Rutin given orally to Wister rats on high-fat diet at a dose of 100 mg/kg/day for 28 days decreased plasma cholesterol, triglycerides, and low-density lipoprotein–cholesterol and had no effect on high-density lipoprotein–cholesterol.394 This flavonoid lowered aspartate aminotransferase, liver weight, and improved hepatic cytoarchitecture.394
Anti-inflammatory effects of Artemisia scoparia and its active constituent, 3,5-dicaffeoyl-epi-quinic acid against activated mast cells
Published in Immunopharmacology and Immunotoxicology, 2018
Sun-Young Nam, Na-Ra Han, So-Young Rah, Youngwan Seo, Hyung-Min Kim, Hyun-Ja Jeong
Artemisia scoparia Waldst. et Kit. (AS) are the perennial herbs of the family Compositae and grows in Korea, Mongolia, India and Japan. The aerial part of AS has been used to treat inflammation, urticaria and hepatitis12–14. Coumarins, essential oils and flavonoids are isolated from AS15. However, the anti-allergic inflammatory effects of AS and its active compound have not yet been studied. Hence, the present study aims to explore the regulatory effect of AS and its major compound, 3,5-dicaffeoyl-epi-quinic acid (DEQA) in activated mast cells.