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Human Skeletal Remains
Published in Cristoforo Pomara, Vittorio Fineschi, Forensic and Clinical Forensic Autopsy, 2020
Francesco Sessa, Dario Piombino-Mascali, Nicholas Márquez-Grant, Luigi Cipolloni, Cristoforo Pomara
Morphometric methods have also been developed. Of these, discriminant function analysis is the best-established method for the estimation of sex. This approach involves recording measurements in supposedly sexually dimorphic samples and using these to develop discriminant functions that permit the sex of the person in question to be estimated (Cabo et al., 2012).
Radiographic Absorptiometry (Photodensitometry)
Published in Stanton H. Cohn, Non-Invasive Measurements of Bone Mass and Their Clinical Application, 2020
Charles Colbert, Richard S. Bachtell
Various morphometric measurements are readily made with the system described. Some measurements (such as the bone width distribution profile and the bone image area) are by-products of the mineral density computation. Also, bone length is automatically measured during a bone scan sequence. In the standard modality, for example, the computer counts the number (n) of scans required to compass the bone from the distal interphalangeal joint to the proximal. The separation between scan line is Δy. The bone length (L) is determined by
Morphometries of Craniofacial Form
Published in D. Dixon Andrew, A.N. Hoyte David, Ronning Olli, Fundamentals of Craniofacial Growth, 2017
The presence of considerable size differences between forms can also act to confuse the analysis of shape and shape changes, suggesting that ways are needed to minimize or remove the potentially confounding effect of size. Moreover, it can be argued that in many cases it is the biologically-based shape information, in contrast to size, which may be of more interest from a morphometric perspective. This leads to the question of how these notions of “size and shape” have been addressed with CMA.
Celiac disease antibody levels reflect duodenal mucosal damage but not clinical symptoms
Published in Scandinavian Journal of Gastroenterology, 2021
Aki J. Käräjämäki, Juha Taavela, Christian Nielsen, Mårten Lönnqvist, Marcus Svartbäck, Katri Kaukinen, Risto Tertti
In most cases, a minimum of three to four representative forceps biopsies were taken from the distal duodenum. The biopsy specimens were paraffin-embedded and standard 5-µm-thick sections were cut and stained with hematoxylin-eosin. Morphometric analyses were done according to our standard operating procedure [4]. Morphometric measurements were done in a blinded manner without knowledge of laboratory, demographic, or original histopathology results. Morphological measurements were performed only on specimens with the plane of sectioning perpendicular to the luminal surface. The small-intestinal mucosal villus height to crypt depth ratio (Vh:CrD) was evaluated from at least three separate villus-crypt units by measuring villi lengths (µm) and crypt depths (µm), and the primary outcome was given as the average of the ratios. IEL densities were counted under light microscopy in HE-stained sections. At least 300 epithelial cells were counted in a continuous length of the epithelium, and the results were expressed as the number of IELs per 100 epithelial cells. Vh:CrD > 2 was considered normal [13].
Test-retest validation of a cranial deformity index in unilateral coronal craniosynostosis
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2020
Emilie Robertson, Peter Kwan, Gorman Louie, Pierre Boulanger, Daniel Aalto
The use of age and sex-matched CT scans as the control group also adheres to the user-friendliness and accessibility criteria outlined for the proposed workflow. More surgeons are likely to have access to a database containing normative skull as opposed to more sophisticated tools like statistical shape models, for example. The reliance on specific multi-atlas’ is a recognized limitation of highly sophisticated quantification methods (Mendoza et al. 2014). Processes that can be carried out without the need for outsourcing or consultation are advantageous from a time and cost perspective. In addition, a user-friendly and inexpensive method to assess reconstruction outcomes may increase clinician productivity in this field. Methods of morphometric quantification that require expert consultation or proprietary software may be a barrier to their regular use. In addition, the cost of using advanced technology is a recognized deterrent (Seruya et al. 2013; Fisher et al. 2016; Martelli et al. 2016; Barbero-García et al. 2017). As methods like statistical shape modelling become more commonplace in the clinical environment, this could replace the use of age and sex-matched CT scans for a more precise workflow.
High-Resolution Imaging of Retinal Vasculitis by Flood Illumination Adaptive Optics Ophthalmoscopy: A Follow-up Study
Published in Ocular Immunology and Inflammation, 2020
Marie-Hélène Errera, Marthe Laguarrigue, Florence Rossant, Edouard Koch, Céline Chaumette, Christine Fardeau, Mark Westcott, José-Alain Sahel, Bahram Bodaghi, Jonathan Benesty, Michel Paques
We reviewed 20 cases of uveitis with retinal vasculitis seen in our department who underwent AOO imaging between June 2014 and March 2016. Images were then examined by three of us (JB, MHE, and MP). The presence of perivascular sheathing was assessed. Images showing acceptable contrast were selected for morphometric analysis. Nine cases were rejected because of a poor contrast of vascular sheathing. Twelve eyes of 12 consecutive subjects (8 women, 4 men; mean age, 42 years) were included in the final evaluation. Diagnoses included birdshot chorioretinopathy (n = 3), toxoplasmic retinochoroiditis (n = 2), ocular tuberculosis (n = 2), MS, idiopathic retinal vasculitis, aneurysm and neuroretinitis (IRVAN), ocular Lyme borreliosis, syphilitic chorioretinitis and idiopathic retinal vasculitis (one case each). Their mean duration of visual symptoms was 7.8 months (range, 1–20) and the mean follow-up was 6.5 months (± 5.6). None was treated by anti-inflammatory treatment at the time of first examination in our department. Their clinical characteristics are summarized in Table 1.