China 
Africa 
Explore chapters and articles related to this topic
Role of Microfluidics-Based Point-of-Care Testing (POCT) for Clinical Applications
Published in Raju Khan, Chetna Dhand, S. K. Sanghi, Shabi Thankaraj Salammal, A. B. P. Mishra, Advanced Microfluidics-Based Point-of-Care Diagnostics, 2022
Arpana Parihar, Dipesh Singh Parihar, Pushpesh Ranjan, Raju Khan
Despite proof-of-concept studies demonstrating the capabilities of microfluidic systems in a variety of ART areas, the majority of clinical applications of microfluidic systems has been in sperm purification or sorting. A key sample preparation process in the treatment of male-factor infertility is the selection of qualitatively and quantitatively sufficient sperm. Sperm-sorting processes based on microfluidic systems can increase motile sperm recovery from semen, sperm recovery from highly heterogeneous mixtures, and potentially reduce clinician ability requirements for the sperm purification process [85–88].
Effect of ultra-sonication and peptization on the aqueous phase stability of iron oxide nanoparticles
Published in Inorganic and Nano-Metal Chemistry, 2020
Amarjeet Bisla, N. Srivastava, Rupali Rautela, Vinay Yadav, Praveen Singh, Abhishek Kumar, S. K. Ghosh, Srikant Ghosh, Rahul Katiyar
Peptization denotes the coating of various acids over the surface of IONPs. Several investigators have attempted covering the surface of IONPs with various acids to prevent their agglomeration and maintain uniform dispersal in the aqueous phase.[20–22] The long term colloidal stability of the IONPs is dependent on the electrostatic and steric repulsion mainly affected by pH.[23–25] The stability of a colloidal system is defined by particles remaining suspended in an equilibrium helped by prevention of agglomeration by Brownian movements. Peptization overcomes this agglomeration by disintegrating agglomerated particles by lowering the surface tension.[22] In the said process, the unbound acidic group of carboxylate dissociates and provides negative charge on the surface of peptized IONPs leading to electrostatic repulsion.[26,27] Moreover, exposition of carboxyl group over the peptized IONPs can be targeted for further functionalization and bio-conjugation for various biomedical applications involving cancer diagnosis, gamete imaging and sperm sorting.[22]
Who gets to be born? The anticipatory governance of pre-implantation genetic diagnosis technology in the United Kingdom from 1978–2001
Published in Journal of Responsible Innovation, 2020
For many people, reproduction is happening in a new, technologically-mediated way. Treatments such as sperm and egg donation, in-vitro-fertilization, cryopreservation of embryos and gametes, womb transplantation, surrogacy, mitochondrial transfer, and others, have impacted how society understands and thinks about genetic ties, heritable illness, parenthood, and reproduction in fundamental ways. New reproductive technologies enable the assessment of, the selection of, and (in the case of gene editing technologies) the editing of embryos that represent the types of people who will be born. While earlier techniques, such as sperm sorting and visual inspection of IVF embryos, enabled the selection of healthy gametes and embryos with some level of success, the ability to genetically assess an embryo prior to implantation in the womb emerged with the genesis of the pre-implantation genetic diagnosis (PGD) technique. PGD is the ability to biopsy a single cell from an in-vitro embryo and test it for characteristics such as sex and genetic mutations. While some feared that PGD and its associated newer technologies, such as gene editing, would ring in an age of new eugenics, others praised the technology as a way of enabling couples suffering from heritable genetic illnesses to have a healthy child of their own. Early on, in the United Kingdom, different elements of society, both formal institutions such as Parliament and regulatory agencies, and non-institutional entities such as advocacy groups and individual members of society, were engaging in questions around the future of PGD technologies, specifically around topics such as: Should it be allowed? Is it akin to eugenic selection? If it is allowed, who will regulate it? And who should have access to it and for what reasons and under what conditions?