Catalog of Herbs
James A. Duke in Handbook of Medicinal Herbs, 2018
Said to alleviate condylomata, sclerosis of the spleen and liver, tumors of the internal organs, mesenteric region, scrotum, sinews, and stomach, as well as corns and warts, and cancer of the breast, face, mouth, and stomach.4 Reported to be astringent, cardiotonic, coagulant, depurative, diuretic, emmenagogue, litholytic, sedative, tonic, vermifuge, and vulnerary; agrimony is a folk remedy for asthma, bronchitis, dermatitis, enterorrhagia, enuresis, gastrorrhagia, hematuria, hepatosis, metrorrhagia, neuralgia, neuritis, pharyngitis, rheumatism, tuberculosis, and warts.32,33 Astringent, the herb tea is useful for internal bleeding, and/or looseness of the bowels. Has a great reputation for curing jaundice and other liver ailments. Also recommended for snakebite. Considered useful in gout, skin eruptions, pharyngitis, diseases of the blood, blotches, pimples, etc. Febrifugal and vermifugal; used for tapeworm, e.g., by the Zulu.3 Sotho use as vermifuge with Artemisia afra; the leaf is used for colds. Plant is gargled for inflammation of throat and mouth. Mixed with fat, it is used as a poultice to draw out indolent ulcers.47
Phytoextracts and Their Derivatives Affecting Neurotransmission Relevant to Alzheimer’s Disease
Akula Ramakrishna, Victoria V. Roshchina in Neurotransmitters in Plants, 2018
The ethyl acetate extract of whole plants of Agrimonia pilosa (Family: Rosaceae) showed significant AChE inhibitory activity due to presence of quercetin [Figure 21.3 (xxxv)]. Inhibitory activity of quercetin is due to the presence of a catechol moiety on ring B, which facilitates quercetin binding to AChE (Natarajan et al., 2009).
Herbal Drug Discovery Against Inflammation: From Traditional Wisdom to Modern Therapeutics
Amit Baran Sharangi, K. V. Peter in Medicinal Plants, 2023
The evidence to support the use of the natural product in medication came into existence in 1805 with the discovery of morphine. There are some plants described in Ayurveda as well as in Ayurvedic Pharmacopeia of India having inflammatory properties such as Curcuma officinalis (Family: Zingibera-ceae), Aralia nudicaulis (Family: Araliaceae) (Lee et al., 2011; Oh et al., 2009; Seo et al., 2007; Wang, Li, Ivanochko, and Huang, 2006; Chung et al., 2005; Park et al., 2005; Ryu et al., 1996). These are the plants extensively studied and addressed for their profound pharmacological activities and also been used as traditional medicine (TM) for the treatment of rheumatoid arthritis, ulcerative colitis, pancreatitis, cancer, and osteoarthritis, etc. Plants such as Bauhinia variegate (aerial part) found to have promising anti-inflammatory activity against the lipopolysaccharides, interferon λ induce nitric oxide (NO) and cytokines (Singh, Singh, and Singh, 2016). Glycyrrhiza glabra and Acacia arabica (Babul) used for respiratory tract infections are mentioned in Ayurveda (Aggarwal et al., 2011). The glycosidal fraction of ethanolic extract of unripe pods of Acacia farnesiana, Aegle marmelos (L.), Correa ex Roxb. (Bael) yields coumarin and marmin from the roots, The plant extract of Ageratum conyzoides of family Asteraceae, mentioned as Dochunty, Berberis aristata of family Berberidaceae commonly known as ‘Daruharidra’ is an evergreen shrub (Khare, 2008). The mucosal inflammation in the oral tract can be treated with Agrimonia eupatoria. The salicylate components of Aloe barbadensis Ghritkumaarika (Mill) or Aloe gel reported to inhibit bradykinin, a pain-producing agent. Blumea lacera called as Kukundara showed marked anti-inflammatory activity in bradykinin and carrageenin-induced inflammation in rats. Boerhavia diffusa Linn, a weed Rakta-punarnavaa found throughout India possess anti-inflammatory property for renal diseases and also possess antiarthritic activity. Ethanolic extract of M. flagellipes decreased the edema at the rate of 11.7% and 54.2% in acute inflammation and 7.00% and 42.40% for chronic inflammation at the dose of 10 and 50 mg/kg induced by carrageenan and formalin (Uchegbu et al., 2015). Magnolia kobas stem bark inhibits the pro-inflammatory mediators (IL-ß, TNFα). The M. kobas treatment suppresses TPA induced ear swelling (in-vitro/in-vivo) (Kang et al., 2008). 4-O-methylhonokiol novel compound isolated from Magnolia officinalis shows anti-inflammatory properties by inhibiting the NF-κB (Oh et al., 2009). The chloroform extract of dried fruits of Babassu mesocarp showed significant anti-inflammatory and analgesic properties (Azevedo et al., 2007). Some other plants have also been reported for having anti-inflammatory activities are given in Table 3.1.
Agrimoniin inhibits the activity of CYP1A2, 2D6, and 3A4 in human liver microsomes
Published in Xenobiotica, 2021
Yanqing Zhou, Qian Xian, Haimin Wei, Jin Zhou, Shengjian Li, Junwei Yang, Xuedong Zhou, Yamei Li
Agrimonia pilosa Ledeb. is traditional folk medicine that has been widely used as haemostatic, antiparasitic, and antidiarrheal agents. Agrimoniin is a major constituent of Agrimonia pilosa Ledeb. and it also existed in some commonly consumed food, such as strawberry and raspberry (Grochowski et al. 2017). The pharmacological properties of agrimoniin have also been widely reported. For example, agrimoniin showed an antitumor effect on fibrosarcoma and enhance immune response (Miyamoto et al. 1987). Herbal medicine is one of the most common treatment methods in paediatrics, which plays a crucial role in the healthcare system and has been used as alternative medicine worldwide. Herbal medicines are complex mixtures, and these complex mixtures may interact with each other, which makes it attract special attention and become largely different from western therapies (Ge 2019). Cytochrome P450 (CYP450) enzymes are key factors during these potential interactions.
Variability, toxicity, and antioxidant activity of Eupatorium cannabinum (hemp agrimony) essential oils
Published in Pharmaceutical Biology, 2016
Asta Judzentiene, Rasa Garjonyte, Jurga Budiene
Eupatorium cannabinum is a medicinal and aromatic herb with antibacterial, immunological, cytostatic, anti-inflammatory, fungicidal, etc. properties. In Lithuanian folk medicine, the plant has been used as a remedy for treatment of liver diseases and against diarrhea (Lekavicius, 1980). Currently hemp agrimony is used as a component for some homeopathic preparations.
Related Knowledge Centers
- Agrimonia Eupatoria
- Agrimonia Gryposepala
- Agrimonia Pilosa
- Commission E