Antineoplastic drugs during pregnancy
Bertis Little in Drugs and Pregnancy, 2006
Cancer is uncommon during pregnancy and occurs in approximately one in 1000-6000 pregnant women (Haas, 1984; Kennedy et al., 1993; Pepe et al., 1989). It can be estimated that one in 118 women with cancer will be pregnant, because 12.8 percent of all cancers in women occur in the 15-44 age group (Third National Cancer Survey, 1975). Population-and hospital-based studies show that the most frequently occurring cancers that present during pregnancy are cervix, breast, and ovary (Haas, 1984; Pepe et al., 1989). The frequencies of nongenital-type cancers during pregnancy are shown in Table 7.1. The frequencies of the various forms of genital cancers in pregnancy are shown in Table 7.2, with cervical cancer being the most common.
Depression During Pregnancy and the Postpartum Period
Sheryl M. Green, Benicio N. Frey, Eleanor Donegan, Randi E. McCabe in Cognitive Behavioral Therapy for Anxiety and Depression During Pregnancy and Beyond, 2018
The experience of sadness or depression during pregnancy or in the postpartum period can be an unsettling experience for new or expecting mothers. This experience, however, is relatively common, with up to 84% of women experiencing the ‘baby blues’ in the early postpartum period and 9–19% of women experiencing postpartum depression. Some women also experience depressive symptoms (e.g., sadness, loss of pleasure) during pregnancy. Chapter 2 provides an overview of these symptoms with the goal of helping women, their families, and their healthcare workers become more familiar with the nature and signs of depression in women during pregnancy and the postpartum. This chapter will help you distinguish between the ‘baby blues,’ clinical depression, and other mental health difficulties (e.g., postpartum psychosis), and to better understand the events or situations that can increase the risk of depression during pregnancy and the postpartum.
Nutritional and dietary supplementation during pregnancy
Bertis Little in Drugs and Pregnancy, 2006
A balanced ‘nonfad’ diet should provide pregnant women with an adequate complement of nutrients during pregnancy. Prenatal vitamin supplements are usually given, but there is no clear consensus that they are needed. Under the Hippocratic dictum of ‘do no harm,’ prenatal vitamin supplements are not harmful in recommended daily allowance (RDA) doses. Vitamin supplements for pregnant women should, along with dietary intake, approximate the RDA set by the Food and Drug Administration (FDA) (Table 12.1). Iron is the only nutrient for which supplementation during pregnancy is invariably required.
Specific dermatoses of pregnancy: advances and controversies
Published in Expert Review of Dermatology, 2010
Specific dermatoses of pregnancy include herpes (pemphigoid) gestationis, polymorphic eruption of pregnancy (also known as pruritic urticarial papules and plaques of pregnancy), prurigo of pregnancy and pruritic folliculitis of pregnancy. This article focuses on what is currently known about the epidemiology, clinical characteristics, etiopathogenesis and management of these disorders. Moreover, it discusses the intrahepatic cholestasis of pregnancy and ‘atopic eruption of pregnancy’, which were recently reclassified as specific dermatoses of pregnancy, as well as debates related to the prevalence and diagnostic criteria of the latter. Finally, it addresses the suggested overlap between ‘atopic eruption of pregnancy’ and specific dermatoses of pregnancy, such as prurigo and pruritic folliculitis.
Pre-pregnancy body dissatisfaction and weight-related outcomes and behaviors during pregnancy
Published in Health Care for Women International, 2021
Rebecca A. Schlaff, Meghan Baruth, Jessika T. Gherke, Samantha J. Deere
To examine relationships among pre-pregnancy body dissatisfaction (BD) and gestational weight gain (GWG), and related attitudes/behaviors. Pre-pregnancy BD was self-reported in early pregnancy. Weight-related attitudes/behaviors were self-reported and physical activity was objectively measured during pregnancy. Overall, 92% of the women reported BD, with 69% desiring a smaller pre-pregnancy size than their actual pre-pregnancy size. Ideal pre-pregnancy weight was 20.7 ± 28 pounds less than self-reported pre-pregnancy weight. Only weight-control strategies used at 35 weeks were associated with BD (p = 0.008). Pre-pregnancy BD may not predict risk for excess GWG and some weight-related issues during pregnancy.
The value of a registry negative urine pregnancy test for the prediction of a future unintended pregnancy among young women
Published in The European Journal of Contraception & Reproductive Health Care, 2018
Misgav Rottenstreich, Sorina Grisaru-Granovsky, Amihai Rottenstreich
Background: Performance of urine pregnancy test in general adolescents’ clinic reflects caregiver or woman’s concern that there might be a pregnancy. We aimed to assess whether young-unmarried women in whom a negative urine pregnancy test was registered would be at increased risk of a future unintended pregnancy. Methods: The study cohort included consecutive women drafted by the Israeli military between 2013 and 2015. The risk of unintended pregnancy was compared between women with a negative urine pregnancy test (n = 2774), the study group, and those in whom urine pregnancy test was not carried out (n = 126,659), the control group. Results: During the study period, 2147 (1.7%) women experienced an unintended pregnancy. The risk of unintended pregnancy was significantly higher in patients in whom a past pregnancy test was negative 4.3% (n = 118), as compared with the control group 1.6% (n = 2028) (odds ratio [OR], 2.7; 95% confidence interval [CI], 2.23–3.26). In multivariate analysis history of a negative pregnancy test results was an independent predictor for a future unintended pregnancy (adjusted OR, 2.0; 95% CI, 1.63–2.52). Conclusions: A history of a negative pregnancy test among young conscripted women is a significant risk indicator for a future unintended pregnancy. Directed efforts should be made in this particular vulnerable group of patients.
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