Efficacy of Neurofeedback for Pain Management
Mark V. Boswell, B. Eliot Cole in Weiner's Pain Management, 2005
First, the improvements across the board tend to support the dysregulation model. Second, it is observed that the most significant quantitative electroencephalography (QEEG) deviations, and the most numerous, consisted of coherence anomalies. This indicates deficits in cortical–cortical communication relationships. Finally, it is observed that the successful training did not directly target the observed deviations. In particular, when suppression of the excess 13-Hz amplitude was first tried, it was found to be relatively ineffectual. Yet a different challenge at a slightly different frequency was found to resolve nearly all of the anomalies. Perhaps surprisingly, single-site training was even effective in normalizing the two-site coherence anomalies. This again supports the dysregulation model. An appropriate challenge, empirically derived, effects broad and nonspecific functional renormalization that will be generally reflected in a tendency toward normalization of EEG parameters.
Is There a Common Etiology for Depression and Anxiety?
Siegfried Kasper, Johan A. den Boer, J. M. Ad Sitsen in Handbook of Depression and Anxiety, 2003
In summary, studies of sleep architecture and symptom provocation offer evidence for differential mechanisms of depressive and anxious symptomatology, while studies of quantitative electroencephalography and cardiovascular regulation suggest a greater degree of physiological overlap. Heightened specificity of physiological measures correlated with emotional symptoms may yield evidence in time of overlapping disease mechanisms for specific subtypes of anxiety and depressive disorders.
The Neuropsychological Consequences of Alcohol and Drug Abuse
John Brick in Handbook of the Medical Consequences of Alcohol and Drug Abuse, 2012
In a review by Strickland et al. (1998), the authors noted how cerebral metabolic and hypoperfusion irregularities are seen in the neuroimaging of the cocaine abuser. In particular, techniques such as CAT and MRI may show significant cerebral events, although newer techniques such as PET, SPECT, and quantitative electroencephalography (QEEG) are able to reveal a greater frequency of changes in brain functioning that may have initially gone unnoticed.
Improved Visual Function in a Case of Ultra-low Vision following Ischemic Encephalopathy Using Transcranial Electrical Stimulation; A Brief Report
Published in Developmental Neurorehabilitation, 2021
Ali-Mohammad Kamali, Mohammad Javad Gholamzadeh, Seyedeh Zahra Mousavi, Maryam Vasaghi Gharamaleki, Mohammad Nami
In general, the application of a novel method with a proper safety profile resulting in a sustained improvement in visual function (at least over a 20 months of follow-up) was the highlight of our study. Meanwhile, more investigation is needed to assess the patient’s vision improvement in a long-term period. Most of the previous studies have articulated the effect of common neurovisual rehabilitation strategies in adults whilst such reports in the pediatric population are scant. Since CVI is an important cause of vision loss in children, it is also necessary to evaluate and recommend the rehabilitation approaches in children and young adults.25 In addition, the employment of noninvasive brain stimulation as a therapeutic approach for visual rehabilitation has not been the case in our setting yet. Other than the above, based on some recent reports, CVI can be characterized as a condition of dorsal stream dysfunction or dorsal stream vulnerability which appears to be the most common type of visual processing impairment observed in children with such a condition. This needs to be focused upon future studies which employ neuroscience imaging approaches including quantitative electroencephalography-included brain mapping26
Medical Art Therapy Research Moves Forward: A Review of Clay Manipulation With Parkinson’s Disease
Published in Art Therapy, 2018
Deborah L. Elkis-Abuhoff, Morgan Gaydos
By embracing the neurological direction that this research has taken, we are in the process of incorporating brain scans to measure the effects that clay manipulation has on the brain with PD. Collaborative efforts in neuroscience, such as a pre- and postbrain scan on an individual with PD who is engaged in clay manipulation art therapy, can help monitor brain wave activity, the presence of dopamine, and whether the observed changes in symptomology could be directly correlated with increased brain stimulation. Brain scans, specifically through use of quantitative electroencephalography and electroencephalograms, which are tests that detect electrical activity in the brain using electrodes attached to the scalp, have been explored in the realm of art therapy as an indication of increased brain wave activity (Belkofer & Nolan, 2016; Belkofer, Van Hecke, & Konopka, 2014; Kruk, Aravich, Deaver, & deBeus, 2014). This neurological application has not been applied specifically to the PD diagnosis. With the observations and quantitative data that our research team has gathered during this clay manipulation investigation, the use of neurological scans appears to be the next natural step to a greater understanding of the impact art therapy has on PD.
New directions in psychiatric drug development: promising therapeutics in the pipeline
Published in Expert Opinion on Drug Discovery, 2023
Linda S. Brady, Sarah H. Lisanby, Joshua A. Gordon
Consortia are playing an important role in developing standardized instrumentation, data collection methods, and data processing and analysis pipelines for translational biomarkers (imaging, neurophysiological, and other measures) to enable the collection of high-quality data that is reliable and scalable for broader use in drug discovery and development [62]. The industry-led Event Related Potential (ERP) Biomarker Qualification Consortium is an example of a pre-competitive effort among industry, academia, and regulators to ensure that robust and reliable ERP and quantitative electroencephalography (qEEG) biomarkers can be effectively collected in target clinical populations, such as patients with schizophrenia, thus ensuring scalability and consistency across studies [63]. The first study from the ERP Consortium established test–retest reliability for ERP qEEG measures, a validated, automated data analysis pipeline, and normative ERP/qEEG datasets in schizophrenia subjects and matched healthy volunteers [64].