Effects of Thermal Cycling on Surface Hardness, Diametral Tensile Strength and Porosity of an Organically Modified Ceramic (ORMOCER)-Based Visible Light Cure Dental Restorative Resin
P. Mereena Luke, K. R. Dhanya, Didier Rouxel, Nandakumar Kalarikkal, Sabu Thomas in Advanced Studies in Experimental and Clinical Medicine, 2021
ORMOCERS are very promising materials. Although ORMOCERS are very promising, few investigations [6] have confirmed the potential of ORMOCERS as biomaterials or low-contraction materials applied to teeth restoration. The two composites (Definite® (Degussa AG, Hanau, Germany) or Admira® (Voco GmbH, Cuxhaven, Germany) available in the market based on ORMOCER technology. Admira composite contained 78% inorganic particles (barium and aluminum silicate) with an average size of 0.7 μ and the organic fraction composed of 65.5%, conventional organic dimethacrylates such as BisGMA, and UDMA along with 34.5% of triethylene glycol dimethacrylate (TEGDMA). The concept of ORMOCER [7] is to combine properties of organic polymers with glass-like materials to generate new/synergistic properties. The processing steps are based on sol-gel type reaction. Our previous studies reported [8–12] the development of a noncytotoxic and biocompatible organically modified ceramic composite with lower polymerization shrinkage compared to a composite containing BisGMA.
Tuning the Properties of Silver Monolayers for Biological Applications
Huiliang Cao in Silver Nanoparticles for Antibacterial Devices, 2017
In the case of sol-gel processes, the sol (e.g. silver suspension) is the starting precursor that is deposited on a substrate to form a film or monolayer of desirable properties. This wet chemical approach is a cheap and low-temperature technique that allows fine control of the product composition and doping elements can be easily introduced (Zhang 2010). Moreover, it is worth emphasising that several efficient coating methods, based on the sol-gel approach, have been developed, among which spin-coating and dip-coating are frequently applied in practice (Hall et al. 1998; Zhang 2010).
Scintillating quantum dots
Sam Beddar, Luc Beaulieu in Scintillation Dosimetry, 2018
In recent years, the sol–gel process has been recognized as an extremely useful strategy to encapsulate scintillant in a glassy matrix, providing an alternative to the porous glass diffusion method used by Létant and Wang (2006). The term sol–gel refers to a process in which solid nanoparticles dispersed in a liquid (a sol) agglomerate together to form a continuous 3D network extending throughout the liquid (a gel). The method used to prepare the sol-gel uses a scintillant that cannot typically be introduced into a high-temperature glass melt.
Biofilm inhibition and antifouling evaluation of sol-gel coated silicone implants with prolonged release of eugenol against Pseudomonas aeruginosa
Published in Biofouling, 2021
Prasanth Rathinam, Bhasker Mohan Murari, Pragasam Viswanathan
Room temperature-processed acid-base catalyzed sol–gels have been used for various biomedical applications due to their widely accepted bioresorbable and biocompatible properties, tailorable composition and microstructure, excellent prolonged release properties, the ease of introducing multiple functional groups or elements, and the possibility of depositing them on any substrata by using inexpensive and straightforward techniques (Brinker and Scherer 2013). The sol–gel process involves the transition of a solution system from a liquid ‘sol’ (mostly colloidal) into a solid ‘gel’ phase through gelation, condensation and drying processes (Dehghanghadikolaei et al. 2018). Large quantities of biological molecules can be added into the porous solution system and uniformly distributed in the concrete matrix. Thus, sol–gels are prepared as thin films, coatings and hydrogels for fire-retardant, anti-static, water/oil repellent, insect-repellent, antimicrobial and catalytic applications, as well as for the encapsulation of enzymes, proteins, growth factors and antimicrobial agents (Brinker and Scherer 2013).
Magnetic carbon nanotubes: preparation, physical properties, and applications in biomedicine
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Mehrdad Samadishadlou, Masoud Farshbaf, Nasim Annabi, Taras Kavetskyy, Rovshan Khalilov, Siamak Saghfi, Abolfazl Akbarzadeh, Sepideh Mousavi
In addition to synthesis of high-grade metal or metal oxides/silica nanocomposites, sol–gel process can be employed for synthesis of metal nanocrystals and oxides/carbon hybrid composites. Hydrolysis and condensation of precursor in solution are fundamentals of this process. The quality, shape, structure, size, and properties of the product could be fully governed regulating the parameters including solvent, temperature, concentration of the precursors, the pH, agitation, and so on [61]. MCNTs also can be prepared by the sol–gel process. In a research by Modugno et al. [62], Fe2O3-MWCNTs nanocomposites were synthesized using a modified sol–gel process. As the first step in this method, the MWCNTs surface was activated with carboxylic acid groups and subsequently, using sol–gel process in which the g-Fe2O3 NPs was attached to the MWCNTs surface, at the same time with their synthesis. The main advantages of sol–gel process are low temperature operation which prevents oxidation of precursors and low cost. However, the nature of this process increases the possibility of product contamination which is the major drawback of sol–gel process.
Intravitreal safety profiles of sol-gel mesoporous silica microparticles and the degradation product (Si(OH)4)
Published in Drug Delivery, 2020
Yaoyao Sun, Kristyn Huffman, William R. Freeman, Michael J. Sailor, Lingyun Cheng
In contrast to electrochemical etching of silicon substrate and subsequent oxidation in the research lab, mesoporous silica particles synthetized by the sol-gel process have been used for drug delivery in various non-ophthalmic applications (Owens et al., 2016; Vlasenkova et al., 2019). The sol-gel process in a large-scale production has many advantages, including significantly higher purity and uniform particle size and pore size. In the current study, sol-gel silica particles without payload are used to generate soluble silicic acid to test cytotoxicity in vitro and sol-gel silica articles with various pore sizes were evaluated in vivo after intravitreal injection. Eye specific information about sol-gel silica particles is meager in literature and the current study aims to explore intravitreal safety of mesoporous sol-gel silica microparticles in the context of a drug delivery vehicle.