Moringa oleifera (Drumstick)
Mehwish Iqbal in Complementary and Alternative Medicinal Approaches for Enhancing Immunity, 2023
Moringa oleifera, also recognised as ‘drumstick', is a species of rapidly expanding tropical plant that belongs to the family Moringaceae (Table 19.2), with thick tuberous roots, seeds, plenty of flowers, green leaves and pendulous extended fruits (Milla et al., 2021). The plant is native to northern India, albeit it is established in Madagascar, southwestern regions of Asia and northwestern and southwestern regions of Africa. It has extensively been a part of long-established horticulture, utilised mostly for decorative reasons in areas near the Pacific seaboard of Mexico (Olson & Fahey, 2011), in addition to plantations in Argentina and Bolivia and some other places in the globe (Milla et al., 2021) (Table 19.1).
Potential Significance of Proteases
Hafiz Ansar Rasul Suleria, Megh R. Goyal, Masood Sadiq Butt in Phytochemicals from Medicinal Plants, 2019
Globally, Moringa oleifera can be used for food and has some advantageous properties. It is a rich source of nutrients, amino acids, antioxidants, and also has anticancer and antiinflammatory properties.77 Moringa could be an enormously important source of food, as it is an extremely good source of sulfur containing amino acids like cystine and methionine, minerals (particularly iron), and vitamins A, B, and C. It can be used in instant noodles, spices, bread, fortifying sauces, juices, and milk.54
Nanotechnology and Anti-Ageing Skin Care
Dilip Ghosh, Pulok K. Mukherjee in Natural Medicines, 2019
Moringa oleifera (Figure 21.3c) is part of the Moringaceae family and is commonly known as the drumstick tree. Traditionally the leaves are used as a purgative, for headaches, sore throat, fevers, piles, eye and ear infections, scurvy, bronchitis, catarrh and to treat sores. Bioactive compounds previously isolated from M. oleifera include vitamin A, vitamin B, vitamin C, β-carotene, carotenoids and phenolics (Anwar et al. 2007; Ali et al. 2013).
Targeting Bone Metastases Signaling Pathway Using Moringa oleifera Seed Nutri-miRs: A Cross Kingdom Approach
Published in Nutrition and Cancer, 2022
Kinjal Bhadresha, Maulikkumar Patel, Jpan Brahmbhatt, Nayan Jain, Rakesh Rawal
Plants have provided a notable base of nutraceuticals, which are used by nearly two-thirds of the world’s population for health advantages and avoidance of diseases. Furthermore, recently a large number of herbs have been developed for their anticancer properties (1, 2). Moringa oleifera belonging to the family of Moringaceae is an effective most useful nutritional and medicinal plant. Moreover, M. oleifera is rich in nutritional value remaining in the presence of a variety of essential phytochemicals present in several organs, such as leaves, pods, and seeds which are edible and are used in numerous countries (including the various regions of Africa) for their high relating nutritional value (3). Almost all tissue from the Moringa plant can be used as a traditional medicine for the treatment of a variety of diseases, such as respiratory distress, skin diseases, ear and dental infections, diabetes, hypertension, anemia, and cancer (4, 5). Additionally, the pharmacological and nutritional values of the seed and leaves extract containing bioactive compounds like antioxidants, vitamins A, B, and C, minerals, proteins, and essential amino acids are well described by Leone et al (2015) (6). A recent study described the effect of In Vitro simulation digestion on the biological activity of M. oleifera against bone metastases from prostate cancer (7).
Aqueous Extract of Moringa oleifera Exhibit Potential Anticancer Activity and can be Used as a Possible Cancer Therapeutic Agent: A Study Involving In Vitro and In Vivo Approach
Published in Journal of the American College of Nutrition, 2021
Dharmeswar Barhoi, Puja Upadhaya, Sweety Nath Barbhuiya, Anirudha Giri, Sarbani Giri
The efficacy of plants toward cancer treatment is attributed to the bioactive compounds present in plants. Scientific reports indicate that bioactive compounds have immense potential to block or suppress cancer (7). Moringa oleifera (MO) is one of the most cultivated angiospermic plants belonging to the family Moringaceae. The plant has nutritional values as it contains high amount of proteins, vitamins and minerals. Different parts of Moringa oleifera have been traditionally used by Indians and Africans in the treatment of more than 300 ailments including cancer (8). The plant possess various bioactive compounds like flavonoids, phenolics, vitamin C (ascorbic acid), α-tocopherol, β-carotenoids, etc. (9–13). The antioxidant, antidiabetic or anti-inflammatory potential of Moringa oleifera can be attributed to the bioactive compounds present in it (14–17).
Moringa oleifera leaf extract induces vasorelaxation via endothelium-dependent hyperpolarization and calcium channel blockade in mesenteric arterial beds isolated from L-NAME hypertensive rats
Published in Clinical and Experimental Hypertension, 2020
Direk Aekthammarat, Patchareewan Pannangpetch, Panot Tangsucharit
Epidemiologic studies support the potential of several medicinal plants to prevent and treat cardiovascular diseases with minimal side effects (6), providing an alternative source of drugs. Moringa oleifera Lam (Moringaceae) is a plant traditionally used as a nutritious food and in herbal medicine. Many kinds of medicinal products from M. oleifera leaves are available in the market nowadays and it has been claimed that some of them have antihypertensive action (7). Moringa oleifera leaves contain flavonoids, phenolic acids, glucosinolates, tannins, and triterpenes, some of which exhibit pharmacological actions in cancer, diabetes, hypercholesterolemia, insulin resistance, nonalcoholic liver disease, and overall inflammation (7). An acute-toxicity study demonstrated that the oral LD50 of M. oleifera leaf aqueous extract exceeds 6,000 mg/kg (8). Preclinical studies have shown that the mustard oil glycosides (thiocarbamates and isothiocyanates) isolated from M. oleifera leaf extract are responsible for the hypotensive activity in anesthetized normotensive rats (9,10).
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