Zearalenone: Insights into New Mechanisms in Human Health
Dongyou Liu in Handbook of Foodborne Diseases, 2018
Fusarium gramineum is an inferior haploid-phase fungus that has two means of reproduction: asexual and sexual. The talus is in the form of filamentous hypha, and it develops chlamydospores through mitosis, thus propagating asexually. After sexual reproduction, through meiotic division, the resulting spores, called ascospores, are formed and organized in structures called ascus [10]. Besides zearalenone, Fusarium sp. produce other mycotoxins, such as enniatin A1, enniatin B1, and enniatin B2 [4]. Other ZEA stereoisomers are also produced by the Ascomycota Fusarium culmorum, F. equiseti, and F. verticillioides.
Assessment of single-nucleotide variant discovery protocols in RNA-seq data from human cells exposed to mycotoxins
Published in Toxicology Mechanisms and Methods, 2023
M. Alonso-Garrido, M. Lozano, A. L. Riffo-Campos, G. Font, P. Vila-Donat, L. Manyes
Mycotoxins are toxic chemical substances produced by filamentous fungi. Commodities such as cereals, nuts, oilseeds, dried fruits, coffee, wine, and their by-products are the most frequently contaminated by mycotoxins crops and substrates (FAO 2020). Even when good practices are applied in food production, storage and distribution chain, mycotoxins remain a concern in food safety. Substantial economic losses are linked to the impact of mycotoxins on human health and animal productivity, including domestic and international trade (Gil et al. 2016). Beauvericin (BEA) and enniatin B (ENB) are two nonlegislated mycotoxins frequently found in cereals and cereal-derived food and feed. They show similar hexadepsipeptides chemical structures (Carballo et al. 2018; Tolosa et al. 2019).
Related Knowledge Centers
- Beauvericin
- Chemical Compound
- Depsipeptide
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