Anal Fissure
Peter Sagar, Andrew G. Hill, Charles H. Knowles, Stefan Post, Willem A. Bemelman, Patricia L. Roberts, Susan Galandiuk, John R.T. Monson, Michael R.B. Keighley, Norman S. Williams in Keighley & Williams’ Surgery of the Anus, Rectum and Colon, 2019
Topical local anaesthetics provide symptomatic relief and can be combined with steroids to promote healing and decrease inflammation. Commercial preparations include combinations of cinchocaine and hydrocortisone. Previous authors have shown high success rates using conservative management alone.1 Others have, however, shown eventual relapse in up to half of all patients followed up, with the presence of a skin tag associated with a poor outcome, likely reflecting a chronic established process.3 Patient adherence to the treatment regimen of topical applications and dietary management can also be difficult once it enters the preventative phase.
Benzocaine
Anton C. de Groot in Monographs in Contact Allergy, 2021
In another study in the United Kingdom, before 1988, 40 patients reacting to a ‘caine mix’ containing 5% benzocaine, 1% dibucaine (cinchocaine) and 1% tetracaine (amethocaine) were tested with its ingredients and there were 19 reactions to benzocaine, 12 to dibucaine and 16 to tetracaine. The most involved primary sites were the legs (29%) and the anogenital region (27%). Relevance for the entire group was a little over 50%, past relevance 19% (78).
Local Anesthetics and Anesthetic Solutions: Classification, Mode of Action and Dosages
Marwali Harahap, Adel R. Abadir in Anesthesia and Analgesia in Dermatologic Surgery, 2019
There are a large number of substances with topical anesthetic properties. Many of them are not used for surgery, but more to relieve itch. Benzocaine is used for itching dermatoses as is cinchocaine. Polidocanol, an agent also used for sclerotherapy of veins and hemorrhoids, is added to certain lotions and bath oil for the treatment of atopic eczema and pruritus. Allergic reactions have often been observed with benzocaine, less frequently with cinchocaine.
Hyaluronic acid gel-core liposomes (hyaluosomes) enhance skin permeation of ketoprofen
Published in Pharmaceutical Development and Technology, 2019
Dana Kawar, Hamdy Abdelkader
There were no statistically significant differences (p > 0.05) among average size diameters for ethosomes, PG-liposomes, transferosomes and hyaluosomes. Further, the effect of PG and ethanol concentrations had no statistically significant (p > 0.05) effects on the average diameter. Similar results were reported elsewhere with cinchocaine PG-liposomes, ethosomes and transferosomes (Elsayed et al. 2007b).
Related Knowledge Centers
- Alkali
- Amide
- Hemorrhoid
- British Approved Name
- Local Anesthetic
- Proctosedyl
- Veterinary Medicine
- Dibucaine Number