Immediate Skin Contact Reactions from Plants
Ana M. Giménez-Arnau, Howard I. Maibach in Contact Urticaria Syndrome, 2014
Autumn-flowering chrysanthemums (Chrysanthemum cultivars, formerly described by some authorities as Dendranthema cultivars) are among the most popular pot (and garden) plants. In light of this, immediate hypersensitivity is rarely reported and only in occupational settings. Tanaka et al. described positive patch test to juice of chrysanthemum leaves and flowers and positive immediate hypersensitivity reaction in a scratch test to diluted flower juice in a female, nonatopic gardener. The controls were negative and the patient’s dermatitis was ascribed to a combination of delayed and immediate hypersensitivity.[43]
Neuroprotective effects of Chrysanthemum morifolium on cerebral ischemia- reperfusion injury contributes to the oxidative stress suppression and related Keap1/Nrf2 pathway
Published in Brain Injury, 2023
Zibin Zhang, Xiaojun Pang, Yuyu Wei, Huai Chen, Xuhong Jin, Qingping Lv
Chrysanthemum morifolium (Chrysanthemum morifolium Ramat; Hangbaiju) belongs to the Asteraceae family, Chrysanthemum genus. The flower of C. morifolium is widely used in China as a herbal medicine and fragrant flower tea for many disease improvement (10). The flavonoids are the major extracts from C.morifolium that contains a wide range of phytochemicals. Pharmacology researches of C. morifolium show that it has antioxidation (11,12), antimicrobial (13), anti-inflammation (14), anti-tumor (15), anti-hyperlipidemia and hypertension (16) and neuroprotective activity (17). Particularly, various studies focused on its antioxidation activity evidence the profound reactive oxygen free radical scavenging and anti-oxidative damage activities. In addition, previous studies report that the active compounds of C. morifolium displayed strong neuroprotective activity on H2O2-induced neurotoxicity in human neuroblastoma SH-SY5Y cells (18,19). The total flavones extracted from C. morifolium were reported to protect against ischemia-reperfusion (I-R) injury in model rats (20). And this reported neuroprotective effect may critically associate with the antioxidative damage activity.
Antioxidant properties of polyphenols from snow chrysanthemum (Coreopsis tinctoria) and the modulation on intestinal microflora in vitro
Published in Pharmaceutical Biology, 2022
Minghao Zhang, Naiyu Zhao, Minhao Xie, Deqiao Dong, Weilin Chen, Yuanpeng He, Dalin Yan, Haiyan Fu, Xinlin Liang, Li Zhou
Coreopsis tinctoria Nutt (Asteraceae), originated in North America and is now distributed worldwide (Guo et al. 2015). Coreopsis tinctoria, an annual herb, possesses important medicinal and economic value. Coreopsis tinctoria is mainly distributed in coastal states of North America, introduced into China around 1900, commonly known as ‘snow chrysanthemum’, which is widely cultivated in the Kunlun Mountain (3000 m above sea level) in the Xinjiang Uygur Autonomous Region of China. The flowers of this plant are widely used as traditional medicines due to the high levels of flavonoids, phenolic compounds, and terpenoids. These bioactive substances endow C. tinctoria with multiple pharmacological activities, especially antioxidant activity is the most important, which is affected by the chemical structures of polyphenols (Chen et al. 2016; Jing et al. 2016; Ma et al. 2016; Li et al. 2019). Few literature references were available for the effects of ultrasonic-assisted extraction on their chemical characteristics and antioxidant properties. Hence, it is necessary to identify and quantify phenolic compounds of snow chrysanthemum (SCPs) and evaluate their antioxidant properties.
Acacetin Alleviates Hepatitis Following Renal Ischemia–Reperfusion in Male Balb/C Mice by Antioxidants Regulation and Inflammatory Markers Suppression
Published in Journal of Investigative Surgery, 2021
Cyrus Jalili, Nasim Akhshi, Farshid Raissi, Abdolhosein Shiravi, Alvand Alvani, Gholamhasan Vaezi, Seyed Ershad Nedaei, Ali Ghanbari
Flavonoids as secondary metabolites of the plants include thousands of compounds and characterized as medicinal plants, dominantly in Chinese herbal medicines [6,7]. Monoflavonoids (e.g., quercitrin) and polyflavonoids (e.g., tetrahydro amentoflavone) are two main categories of flavonoids which the type of polyflavonoids is generally appointed as bioflavonoids [6,7]. Five main subgroups of natural bioflavonoids have been identified [8–10]. Although as shown in Figure 1, the ACA (5,7-dihydroxy-40-methoxyflavone) is a natural monoflavone compound which its medicinal properties is confirmed by many studies, the rest are skeptical in this regard. In 2017, Andrade research team compared the bioactive constituents of brown, green, and red species of Brazilian propolis. Although the ACA was involved in flavonoid contents, their results represented more antioxidant capacity in phenolic compounds than flavonoids [11]. Another experiment compared the constituents of purple Chrysanthemum with a commercially available yellow chrysanthemum and their antioxidant properties. They indicated that, although the yellow Chrysanthemum contains high amount of ACA, but it has less antioxidant property than the purple Chrysanthemum which is rich in anthocyanin [12]. Han and colleagues confirmed high antioxidant activity of phenolic constituent in Chrysanthemum than its flavonoids [13].
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