Alternative and Complementary Medicine in Treating Fungal Dermatophytic Infections
Anne George, K. S. Joshy, Mathew Sebastian, Oluwatobi Samuel Oluwafemi, Sabu Thomas in Holistic Approaches to Infectious Diseases, 2017
Solanum nigrum L. (Solanaceae) is commonly called black nightshade, is an annual herbaceous plant, which can reach upto 100 cm in height. The stem may be smooth or bear small hairs. The flowers usually white in color, have five regular parts and are up to 0.8 cm wide. The leaves are alternate and somewhat ovate with irregularly toothed wavy margin and can reach 10 cm in length and 5 cm in width. The fruit is a round fleshy berry up to 2 cm in diameter and yellowish when ripe. The seeds are brown and numerous (1998) reported the anti-dermatophytic activity against M.canis, T.mentagrophytes and T.violaceum showing MIC value about 8.0 ± 2.82, 61.5 ± 10.13 and 81.2 ± 10.83 μg/mL respectively. Ethanolic and aqueous extract significantly inhibited the Trichophyton species and no effect on Epidermophyton floccosum (Shamin et al., 2004).
Natural Products as Economical Agents for Antioxidant Activity
Hafiz Ansar Rasul Suleria, Megh R. Goyal, Masood Sadiq Butt in Phytochemicals from Medicinal Plants, 2019
Human are utilizing the Glycyrrhiza species (Licorice) since 4000 years to cure different diseases especially cough. More than 30 species are included in the genus Glycyrrhiza and 15 out of 30 have been studied regarding their medicinal use. Glycyrrhiza glabra is being used in the preparation of varying medicines.29 Key component of G. glabra as shown Table 8.1 is glycyrrhizic acid (triterpene glucoside), which is 50 times more sweet as compared with sugar.144 Root extract of licorice is good to cure liver diseases and its antioxidant activities were studied by performing DPPH Assay.29,58 In Indo-Pak subcontinent, Salanum nigrum L (commonly called Black nightshade) has broad uses in medicines.117 The different parts of Solanum nigrum such as stem fruit and leaves against different assays are rich source of antioxidative compounds.143
Catalog of Herbs
James A. Duke in Handbook of Medicinal Herbs, 2018
Toxicity — Mortality or severe poisoning has been described for cattle, chickens, ducks, horses, sheep, and swine.14 Solanine in doses of 200 to 400 mg will induce, in humans, gastroenterosis, tachycardia, dyspnea, vertigo, sleepiness, lethargy, twitching of the extremities, cramps.33 Solanine is also said to exhibit teratogenic properties.302 Other symptoms for poisoning by the plant include diarrhea, mydriasis, panic, excitation, coma, hyperthermia, later dazed state, paralysis, rarely fatality due to respiratory difficulty and hypothermia (more normally due to respiratory paralysis). Black nightshade can contain up to 2.5% N as NO3 and can cause nitrate toxicity. In cattle acute nitrate toxicity leads to death, but chronic toxicity may lead to decreased milk yield, abortion, and impaired vitamin A and iodine nutrition. The proposed LD50 is 160 to 224 mg/NO3/kg.302
Plant poisonings in Australia: a retrospective series of calls to the Queensland Poisons Information Centre
Published in Clinical Toxicology, 2023
Tamim Islam, Robert Knoeckel, Carol Wylie, Katherine Isoardi
Across the few studies that investigate the epidemiology of plant poisonings, plant exposure patterns vary by geography. In the United States, one southwestern study reported cactus, Oleander, and Lantana as the most common plant-related exposures [6]. In New Zealand, black nightshade (Solanum nigrum), arum lily (Zantedeschia aethiopica), and kōwhai (Sophora spp.) predominate [5]. In Thailand, physic nut (Jatropha curcas), wild yam (Dioscorea hispida), and cassava (Manihot esculenta) are the most common exposures [7].
Neuroprotective properties of solanum leaves in transgenic Drosophila melanogaster model of Alzheimer's disease
Published in Biomarkers, 2022
Opeyemi B. Ogunsuyi, Tosin A. Olasehinde, Ganiyu Oboh
Samples [Solanum macrocarpon L (African eggplant [AE]) and Solanum nigrum L, (Black nightshade [BN] leaves) were obtained and prepared as previously described (Ogunsuyi et al. 2021b) The LC-MS/MS and HPLC characterisation for constituent phenolics and alkaloids in both samples as reported in our preliminary study (Ogunsuyi et al. 2021b) are presented in supplementary table S1 and supplementary figure S1).
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