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Bacitracin
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Bacitracin is a mixture of at least nine related cyclic polypeptides (of which bacitracin A is the major constituent) produced by organisms of the licheniformis group of Bacillus subtilis var. Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn’t work well orally. It is mainly used in ointment form for topical treatment of a variety of localized skin and eye infections caused by gram-positive bacteria, as well as for the prevention of wound infections In pharmaceutical products, both bacitracin and bacitracin zinc (CAS number 1405-89-6, EC number 215-787-8, molecular formula C122H201N33O33S2Zn) may be employed (1).
Metronidazole
Published in M. Lindsay Grayson, Sara E. Cosgrove, Suzanne M. Crowe, M. Lindsay Grayson, William Hope, James S. McCarthy, John Mills, Johan W. Mouton, David L. Paterson, Kucers’ The Use of Antibiotics, 2017
Other agents with activity against Giardia include quinacrine (Chapter 191, Iodoquinol and Quinacrine), furazolidine (Chapter 189, Furazolidone), paromomycin (Chapter 185, Paromomycin), and bacitracin zinc (Chapter 83, Bacitracin and Gramicidin) (Kavousi, 1979; Levi et al., 1977; Gardner and Hill, 2001; Upcroft and Upcroft, 2001b; Ortiz et al., 2001; Abboud et al., 2001; Adagu et al., 2002).
Surgical management of severe facial trauma after dog bite: A case report
Published in Acta Oto-Laryngologica Case Reports, 2020
Bernhard Prem, David Tianxiang Liu, Bernhard Parschalk, Boban M. Erovic, Christian A. Mueller
Surgery was performed by the senior author and started within 4.5 h after the attack. The first step was adequate cleansing and rinsing of the wound using povidone-iodine solution for 15–20 min, followed by marginal necrosectomy and debridement. Nasal airway reconstruction began with fixation of the nasal septum. Next, the mucosa of the nasal cavity was attached to the nasal vestibule to reconstruct the passage between the nostrils and the nasal cavity. Absorbable sutures (Vicryl® 5-0) were used to perform multilayer closure of the wounded oral vestibule in the area of the upper lip, resulting in the implementation of a proper vermilion border. Finally, the wound was closed from the left cheek, underneath the nasal root to the right lateral side of the nose, using multiple layers with as little tension as possible (Figure 3). At the end of the surgery, a nasogastric tube was inserted to avoid oral nutrition and bacitracin zinc/neomycin ointment was applied on the wound. Following surgical treatment, the patient was transferred to the intensive care unit for one night.
Gonadal hormones influence core body temperature during calorie restriction
Published in Temperature, 2019
Rigo Cintron-Colon, Kokila Shankar, Manuel Sanchez-Alavez, Bruno Conti
Hormonal replacement was performed 14 d post gonadectomy during ad libitum feeding. Commercially available sterile slow-release pellets were purchased from Innovative Research of America (Sarasota, FL, USA): 17β-estradiol (0.5 mg/21 d), 5α-dihydrotestosterone (5 mg/21 d), and progesterone (10 mg/21 d). Pellets dose was determined following our previous study, and they were implanted subcutaneously as previously described [19]. Briefly, an incision was made along the dorsal midline immediately posterior to the scapulae, just large enough to allow passage of the device. The sterile pellet was placed under the skin in the subcutaneous region. Absorbable sutures were used to close the dorsal incision, and the skin was closed with non-absorbable sutures. In order to minimize the incidence of infection, topical antibiotic treatments (Bacitracin Zinc Ointment) were applied after the completion of surgical procedures.