Blood flow
Peter R Hoskins, Kevin Martin, Abigail Thrush in Diagnostic Ultrasound, 2019
Concerning stenosis: Minor disease (<50% stenosis by diameter) is associated with an increase in flow rateMinor disease (<50% stenosis by diameter) is associated with a decrease in flow rateMajor disease (>75% stenosis by diameter) is associated with an increase in flow rateMajor disease (>75% stenosis by diameter) is associated with a decrease in flow rateTotal occlusion (100% stenosis) is associated with an increase in flow rate
Conditions of the External Ear
R James A England, Eamon Shamil, Rajeev Mathew, Manohar Bance, Pavol Surda, Jemy Jose, Omar Hilmi, Adam J Donne in Scott-Brown's Essential Otorhinolaryngology, 2022
Solid atresia consists of a continuous block of fibrosis from the TM. Membranous atresia is typified by a fibrous tissue that has a covering of canal skin on both sides, separating the ear canal into two segments. The medial segment inevitably collects keratin, which may become erosive. Stenosis may also cause this. Atresia may be caused by the following processes: InflammationChronic OEChronic otitis mediaTraumaBurnsSurgery especially involving a meatal approach
How to dissect the plane between the scar of a laminectomy defect in the posterior thoracic and lumbar spine
Gregory D. Schroeder, Ali A. Baaj, Alexander R. Vaccaro in Revision Spine Surgery, 2019
Magnetic resonance imaging (MRI), with and without IV contrast, is critical to determine areas of compression of neural elements. The addition of gadolinium can help distinguish peridural fibrosis from recurrent disc herniation or residual stenosis. Additionally, MRI will show an asymptomatic contained pseudomeningocele, which may need to be avoided or addressed. MRI imaging must also be carefully examined to determine the site of stenosis: central, lateral recess, or foraminal. Examination of the residual bony anatomy (both normal and previously altered) to establish how much additional bony resection may be required. This distinction will allow an appropriate surgical plan to maximize chances of success. MRI will show the transition zone between native and previously operated anatomy in order to find a safe entry point for dissection (Figure 3.1). In patients with previous instrumentation, visualization of neural elements is obscured due to artifacts. In these situations, computed tomography (CT) myelogram can be useful.
Modelling and simulation of fluid flow through stenosis and aneurysm blood vessel: a computational hemodynamic analysis
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2023
J. V. Ramana Reddy, Hojin Ha, S. Sundar
In the present study, the stenosis is assumed to be mild. Therefore, the parameters associated with the mild stenosis i.e., l, the model behaves as a Newtonian model. The γ, and the subscript T and C is corresponding to the coefficient of thermal expansion due to temperature and concentration, respectively. The expression to compute the Brownian motion parameter and thermophoresis parameter are
Balloon-mounted versus self-expanding stents for symptomatic intracranial vertebrobasilar artery stenosis combined with poor collaterals
Published in Neurological Research, 2019
Yong Zhang, Gary B. Rajah, Peng Liu, Yujie Sun, Tonghui Liu, Xin Li, Zhongrong Miao, Guangwen Li
This study was a retrospective single-arm registry analysis of a prospectively maintained stroke database from 20 participating stroke centers in China. This study included all consecutive patients with intracranial vertebrobasilar artery atherosclerotic stenosis who were treated by balloon-mounted stents or balloon plus self-expanding stents from September 2013 until January 2015. All the participating stroke centers were required to obtain local institution review board or ethics committee approval in accordance with the Health Insurance Portability and Accountability Privacy Act. Written and verbal informed consent was obtained from patients according to the Helsinki Declaration. The diagnosis of stenosis was confirmed by at least one imaging modality, including computer tomography angiography (CTA) or magnetic resonance angiography (MRA) and further validated by digital subtraction angiography (DSA). The therapy was decided by a central adjudication committee composed of designated neurologists, neurosurgeons and radiologists. The conduction, safety and efficacy of the study were monitored by an independent Data and Safety Monitoring Board.
CJP Special Edition—Proceedings of the Michael G. Degroote Institute for Pain Research and Care Annual Symposium—Director’s introduction
Published in Canadian Journal of Pain, 2020
Norm Buckley
One of the very challenging clinical problems in pain care is dealing with the effects of spinal stenosis. Dr. Luciana Macedo of the McMaster School of Rehabilitation Science has received seed grant funding to analyze historical data about spinal stenosis from the Canadian Spine Outcomes Research Network database and reports on this protocol here. Dr. Cheryl Chow, a postdoctoral researcher in the McMaster Department of Psychology, has a research program examining pediatric perioperative anxiety. The review she presents here is an extension of that body of work, specifically examining the effects of anxiety on persistent postsurgical pain in pediatrics. This review highlights several areas for future work to address the significant gaps in the literature. Finally, doctoral student Chad Brown, under the supervision of Dr. Karun Singh of the Stem Cell Research Institute, reports on a novel exploration of work connecting the genetics of autism and pain in developing a neuronal cell model upon which to test novel therapeutics.
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